scholarly journals Comparing the effect of diode laser against acyclovir cream for the treatment of herpes labialis

Author(s):  
M Honarmand ◽  
L Farhadmollashahi ◽  
E Vosoughirahbar
Author(s):  
Parisa Hajian ◽  
Amir Mansour Shirani ◽  
Maryam Khosravi

Introduction: Recurrent Herpes Labialis (RHL) is a common infection and occurs in 20 to 40% of the general population. Risk for transmission exists in dental treatments. There are several different treatments for it. The purpose of this study is a comparison between low-level Laser therapy (LLLT) and acyclovir cream for the treatment of it. Materials & Methods: This performed study was a semi-blind clinical trial in the Oral Medicine Department, Dental School, Islamic Azad University Isfahan Branch (Khorasgan) in the year 2015- 2016. 30 patients got divided into 2 similar groups. Patients in LLLT group, treated in 3 sessions every other day, received 660 nm laser irradiation,100mW,4 J/cm2, continuous, located at a distance of 1 mm from the lesion for 40 seconds. Patients in the medication group treated with 5% acyclovir cream five times a day. In both groups severity of pain and lesion size during treatment and healing time recorded. The collected data were analyzed using statistical tests including independent T-test and Repeated Measures ANOVA ( p value < 0.05). Results: The laser group had better statistically findings for the median time for pain relief (p value < 0.001), and the median time for healing (p value < 0.001), the median lesions size two days after treatment (p value = 0.03), and four days after treatment (p value = 0.003). Conclusion: According to data analysis, laser 660 nm is more effective in pain relief and lesions size reduction and healing time than topical acyclovir in patients with herpes labialis.


BMJ ◽  
1985 ◽  
Vol 291 (6487) ◽  
pp. 7-9 ◽  
Author(s):  
M Shaw ◽  
M King ◽  
J M Best ◽  
J E Banatvala ◽  
J R Gibson ◽  
...  

BMJ ◽  
1985 ◽  
Vol 291 (6498) ◽  
pp. 825-826
Author(s):  
M. Shaw ◽  
J. Best ◽  
J E Banatvala

BMJ ◽  
1985 ◽  
Vol 291 (6491) ◽  
pp. 352-352
Author(s):  
J W Farquhar

2008 ◽  
Vol 19 (3) ◽  
pp. 176-181 ◽  
Author(s):  
Ina Zschocke ◽  
Christine Reich ◽  
Andrea Zielke ◽  
Nadja Reitmeier ◽  
Kristian Reich

1996 ◽  
Vol 57 (4) ◽  
pp. 243-250 ◽  
Author(s):  
Vibeke Ottevanger ◽  
John Larsen ◽  
Susanne Høybye ◽  
Ole Eskerod

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