scholarly journals Salmonella Kentucky: prevalence and challenges in Nigeria and the Africa continent

2020 ◽  
Vol 21 (4) ◽  
pp. 272-283
Author(s):  
E.E. Igomu

Salmonella Kentucky is ubiquitous in most African countries and the multidrug resistant (MDR) strains remain underreported across the continent. In Nigeria, poverty, inter country livestock trades, nomadic system of cattle production, indiscriminate use of antibiotics and prevalent immuno-compromising diseases such as human immunodeficiency virus/acquired immune deficiency syndrome (HIV/AIDS) and tuberculosis are factors that have enabled ease of transmission and complications of S. Kentucky infections. In the present decade, S. Kentucky is reported to be the most prevalent serovar associated with poultry in Nigeria, but very few reports underline the risk associated with consumption of poultry and acquisition of MDR S. Kentucky strains. The Nigerian poultry is one of the most commercialized subsectors of Nigerian agriculture, therefore, the presence of S. Kentucky especially strains carrying broad spectrum antimicrobial resistance pose a great risk to public health. The lack of proper monitoring, surveillance, isolation and control of the multidrug resistant S. Kentucky will remain a challenge to the export potential of the Nigerian poultry subsector and livestock in general. As a nation, modalities and actions against the smuggling of poultry products, indiscriminate use of antibiotics and nomadic system for the production of dairy and beef that promotes spread of virulent strains of Salmonellae must change. The impact of non-typhoidal salmonellosis in humans in Nigeria also remains under studied and under reported, especially those caused by S. Kentucky ST198. Compounding these concerns is the lack of commercial veterinary or human vaccines against S. Kentucky or where vaccines against the broad serogroup C non-typhoidal Salmonella (NTS) are available, they are rarely supplied, with no evidence they could be cross-protective. This review emphasizes the emergence and widespread occurrence of MDR S. Kentucky strains on the African continent, and discussed risk factors contributing to its spread in Nigeria and the potential public health challenge especially to high-risk immunocompromised individuals. Keywords: Salmonella Kentucky, ST198 strain, multidrug resistant, tuberculosis, HIV/AIDS, Nigeria, Africa French Title: Salmonella Kentucky: prévalence et défis au Nigeria et sur le continent africain Salmonella Kentucky est omniprésente dans la plupart des pays africains et les souches multirésistantes (MDR) restent sous-déclarées à travers le continent. Au Nigéria, la pauvreté, les échanges de bétail entre pays, le système d'élevage nomade, l'utilisation aveugle d'antibiotiques et les maladies immunodéprimantes prévalentes telles que le virus de l'immunodéficience humaine/le syndrome d'immunodéficience acquise (VIH/SIDA) et la tuberculose sont des facteurs qui ont facilité la transmission et complications des infections à S. Kentucky. Au cours de la présente décennie, S. Kentucky serait le sérotype le plus répandu associé à la volaille au Nigéria, mais très peu de rapports soulignent le risque associé à la consommation de volaille et à l'acquisition de souches MDR S. Kentucky. La volaille nigériane est l'un des sous-secteurs les plus commercialisés de l'agriculture nigériane, par conséquent, la présence de S. Kentucky, en particulier les souches présentant une résistance antimicrobienne à large spectre, pose un grand risque pour la santé publique. L'absence de suivi, de surveillance, d'isolement et de contrôle adéquats du S. Kentucky multirésistant résistera toujours au défi du potentiel d'exportation du sous-secteur de la volaille nigérian et du bétail en général. En tant que nation, les modalités et les actions contre la contrebande de produits de volaille, l'utilisation aveugle d'antibiotiques et le système nomade pour la production de produits laitiers et de boeuf qui favorisent la propagation de souches virulentes de salmonelles doivent changer. L'impact de la salmonellose non typhoïde chez l'homme au Nigeria reste également sous-étudié et sous-signalé, en particulier ceux causés par S. Kentucky ST198. À ces inquiétudes s'ajoute le manque de vaccins commerciaux vétérinaires ou humains contre S. Kentucky ou là où des vaccins contre les Salmonella non typhoïde du sérogroupe C sont disponibles, ils sont rarement fournis, sans aucune preuve qu'ils pourraient être de protection croisée. Cette revue met l'accent sur l'émergence et la présence généralisée de souches MDR S. Kentucky sur le continent africain, et a discuté des facteurs de risque contribuant à sa propagation au Nigéria et du défi potentiel de santé publique en particulier pour les personnes immunodéprimées à haut risque. Mots-clés: Salmonella Kentucky, souche ST198, multirésistante, tuberculose, VIH/SIDA, Nigéria, Afrique  

2011 ◽  
Vol 6 (3) ◽  
pp. 126
Author(s):  
Toha Muhaimin ◽  
Budi Utomo ◽  
Dharmayati B. Utoyo ◽  
Nia Kurniati ◽  
Triyanti Anugrahini ◽  
...  

Anak penderita Human Immunodeficiency Virus/Acquired Immune Deficiency Syndrome (HIV/AIDS) di Indonesia memperlihatkan tren yang semakin meningkat karena meningkatnya proporsi perempuan terinfeksi HIV/AIDS. Pertimbangan pada dampak besar yang dihadapi anak penderita HIV mendorong kebutuhan pengembangan instrumen khusus untuk mengukur kualitas hidup mereka. Penelitian ini bertujuan mengembangkan instrumen kualitas hidup anak penderita AIDS dengan memodifikasi instrumenyang ada sesuai dengan konteks Indonesia. Pada penelitian ini ditemukan hasil bahwa instrumen yang dikembangkan mempunyai reliabilitas yang cukup baik pada balita dan anak usia 5 – 11 tahun. Nilai reliabilitas (Cronbach’s Alpha) balita, domain fungsi fisik, fungsi sosial, dan gejala HIV masing masing adalah 0,71; 0,72; dan 0,88, sedangkan pada anak 5 – 11 tahun, domain fungsi-fungsi fisik, psikologis, sosial, sekolah, dan gejala terkait HIV masing-masing 0,76; 0,89; 0,67; 0,67; dan 0,88. Penelitian ini menunjukkan untuk konteks Indonesia, nilai ambang batas CD4 yang menunjukkan perbedaan kualitas hidup adalah 15%. Pada balita, dari berbagai ketiga domain, hanya domain gejala terkait HIV yang cukup sensitif untuk mendeteksi perbedaan kualitas hidup anak, sementara pada anak 5 – 11 hanya domain fungsi fisik dan fungsi psikologis yang cukup sensitif untuk mendeteksi perbedaan kualitas hidup anak. Penelitian ini menunjukkan bahwa dampak HIV pada anak masih terkonsentrasi pada gangguan fungsi fisik, fungsi psikologis, dan gejala terkait HIV.Kata kunci: Instrumen pengukuran, anak terinfeksi HIV, kualitas hidupAbstractChildren with HIV/AIDS in Indonesia are increasing due to the increase of woman with HIV. A special instrument for measuring quality of life (QoL) of children with HIV is needed to be developed as the great impact of the infection to children. This study was conducted by modifying the existing QoL instrument of children for Indonesian context. The study indicated that thereliability of the instrument is quite good both for children under 5 and 5 – 11 years old. Reliability values (Cronbach’s Alpha) for under 5, domains of physical function, social function, and HIV-related symptoms are 71, 72, and 88 respectively while for children 5 – 11 years old, domains of physical, psychological, social, and school functions, and HIV-related symptoms are 76, 89, 67, 67, and 88 respectively. The study showed, for Indonesian context, 15% of CD4 is indicated as the threshold to detect the difference of QoL forchildren with HIV. However, for under 5 years old, only questions of HIV-related symptoms domain which is sensitive to detect difference QoL, whereas for children of 5 – 11 years old, the questions concerning physical and psychological domains which are sensitive to detect difference QoL. The study indicated that the impact of HIV on children is mostly on physical andpsychological functions and HIV-related symptoms.Key words: Measurement instrument, children with HIV, quality of life


2020 ◽  
Vol 5 (2) ◽  
pp. 149-166
Author(s):  
Laura E. Jacobson

In 2003, the George W. Bush administration passed the President’s Emergency Plan for AIDS Relief (PEPFAR), a US government initiative to address the human immunodeficiency virus/acquired immune deficiency syndrome (HIV/AIDS) epidemic primarily in Africa. PEPFAR’s US$18 billion budget remains the largest commitment from any nation towards a single disease and has saved countless lives. Given the historical and current political resistance to foreign aid, PEPFAR’s drastic spike in spending on HIV/AIDS raises questions over how the policy process resulted in bipartisan support. Using two policy process theories, punctuated equilibrium theory (PET) and the Narrative Policy Framework (NPF), this analysis helps explain the framing of the global HIV/AIDS epidemic and the factors that resulted in the creation of PEPFAR. The analysis of the PEPFAR policy process reveals a ‘tipping point’ in the early 2000s, when political actors, the media and advocacy coalitions benefitted from issue framing, narrative change and measures of political attention to elevate the global HIV/AIDS crisis to the public agenda. The findings highlight an increase in presidential attention, the evolution of the HIV/AIDS narrative away from stigma and the formation of powerful coalitions. Looking back on the combination of policy process factors that led to PEPFAR’s bipartisan success might lead to insights for dismantling the grand public health challenges of the present and future. This study’s findings have implications for currently stigmatised public health crises, such as the opioid epidemic.


Author(s):  
Laveena D’Mello ◽  
Meena Monteiro ◽  
Sathyendra Prakash

Acquired Immune Deficiency Syndrome (AIDS) is the leading cause of death in children under age five, in many parts of Africa and South East Asia. The interval between exposure to Human Immunodeficiency Virus (HIV) and the development of AIDS is shorter in children than in adults. Infants infected with HIV have a high chance of developing AIDS within one year and dying before age three. In the remainder, AIDS progresses more slowly; the average child patient survives to adolescence. In the past, the world has faced many pandemics like cholera and plague. At the turn of the 20th century, the world faced influenza pandemic [1]. Every fifty to sixty years, the world has faced a new disease that has been of the nature of an epidemic. These diseases have left a trail of death and morbidity. There has been widespread fear and stigma attached to the victims due to ignorance and fear. As the diseases have progressed people have made efforts to study the issues. They have found the cause, spread, cures, and vaccines to prevent the spread of the disease. The aim of the study is to know the Impact of HIV/AIDS on the Psychosocial Development of Children and the objectives are to study the knowledge and awareness about HIV/AIDS. And to study the psychosocial problems faced by the children. In this regard, the researcher conducted a survey of 50 samples of children below the age group of 18 from the community.


2018 ◽  
Vol 1 (1) ◽  
pp. 1-14
Author(s):  
Nicole Naadu Ofosu ◽  
L. Duncan Saunders ◽  
Gian Jhangri ◽  
Afif Alibhai

The impact of the widespread availability of antiretroviral therapy (ART) on the human immunodeficiency virus and acquired immune deficiency syndrome (HIV/AIDS) related attitudes, behaviours and practices of the general population in Sub-Saharan Africa is understudied. We assessed the impact of ART availability on the fear of HIV/ AIDS (measured at both community and personal levels) and HIV prevention practices in Rwimi, Uganda using a cross-sectional survey. The fear of HIV/AIDS was described as a perceived threat to either self and/or community regarding the risk of contracting the disease, whereby the higher the perception of the threat, the greater the fear. We assessed associations between the outcomes of the dependent variables on both the community and personal fear of HIV/AIDS, and the independent variables of HIV/AIDS-related knowledge and demographics. Qualitative data was also generated from focus group discussions (FGD) on the context of the fear of HIV/AIDS and HIV pre- vention practices. The majority of participants (89.4%; males - 86.8%; females - 90.8%) felt that ART availability has reduced the fear of HIV/AIDS in the community. In contrast, fewer participants (22.4%; males - 24.4%; females – 21.2%) mentioned that their personal fear of HIV/AIDS has been reduced with the availability of ART. From the qualitative study, factors identified as influencing the fear of HIV/AIDS included stigma, fear of infection, and the inconvenience of being on ART. Although fear of HIV/AIDS persists, the fear is reduced because of the availability of life-prolonging ART. HIV prevention practices are influenced by socio-cultural norms (gender roles, relationship dynamics, power and trust), which, we argue, should be considered when de-signing sustainable HIV/AIDS prevention programs.


1987 ◽  
Vol 3 (2) ◽  
pp. 306-318

The appearance of acquired immune deficiency syndrome (AIDS) has brought suffering and death to those who are afflicted and, at the same time, has posed daunting challenges to those who care for the sufferers, to biomedicai scientists, and to those responsible for public health and public policy. Among these challenges is the protection of the nation's blood supply from contamination by human immunodeficiency virus (HIV),1 the causative agent of AIDS. This challenge was met rapidly by the development of laboratory tests to detect the presence of antibody against the virus. The application of these tests makes it possible to determine whether the person has been infected by the virus at some time and thus to exclude persons from donating blood or to discard blood already donated. In the past 15 months, the widespread application of these tests along with self-deferral and removal of HIV-positive subjects from the pool of donors has sharply reduced the likelihood of the virus being spread by way of blood products.


Author(s):  
Omphemetse S Sibanda

This paper evaluates the Canadian and the European Union's (EU) implementation of the World Trade Organisation (WTO) General Council Decision of 2003, which resolved that developed nations could export patented pharmaceutical drugs to member states in order to address public health challenges such as Human Immunodeficiency Virus/Acquired Immune Deficiency Syndrome (HIV/AIDS), tuberculosis, malaria and other epidemics, such states including Sub-Saharan Africa (SSA). The author makes a primarily textual appraisal of how and to what extent the Canada Access to Medicine Regime (CAMR) and European Union (EU) Regulations benefit, for instance, SSA countries in the WTO in their quest to make essential medicine more accessible. The author argues that although there are identifiable complexities inherent in the Canadian and the EU's access to pharmaceutical product regimes, there are far more important incentives and benefits that can be reaped in taking advantage of the respective systems. The author recommends that countries facing public health crises/emergencies, such as SSA countries, and non-governmental organisations (NGOs) take advantage of the regulatory flexibilities of Canada and the EU in their efforts to provide their communities with essential HIV/AIDS treatment, and treatment for other diseases such as malaria. The author dismisses the arguments against TRIPS (Trade-Related Aspects of Intellectual Property) flexibilities-inspired legislation and similar measures as mostly mere rhetoric and hair-splitting, because they sometimes unwarrantedly dismiss a workable solution to public-health problems. 


2020 ◽  
pp. 59-69
Author(s):  
Aulia Apriliani ◽  
A. Rizki Amelia AP ◽  
Arni Rizqiani Rusyidi

Acquired Immune Deficiency Syndrome (AIDS) is interpreted as a symptom or disease caused by decreased immunity due to infection with Human Immunodeficiency Virus (HIV). The highest HIV/AIDS sufferers by age in South Sulawesi Province in 2019 are aged 15-29 years and Makassar City is the city with the highest number of sufferers HIV/AIDS as many as 430 people. The purpose of this study was to determine adolescent perceptions about HIV/AIDS in Community Based Organizations (OBK) in Makassar City in 2020. The type of research used was qualitative with a phenomenological approach. The informants in this study consisted of key informants, supporting informants, and ordinary informants who done with the snowball sampling method. From the results of the study it was found that adolescents who are members of the Makassar State University MAPHAN UKM show the perception of the vulnerability of girls knowing the risk of disease. The perception of seriousness shows that adolescents know the seriousness of an individual's illness by explaining and determining the impact of the risks and conditions. Perception Encouragement to act shows that adolescents already know the urge to make prevention efforts to the community by explaining and providing awareness to the community. Perception of benefits shows that adolescents already know the benefits of HIV/AIDS prevention efforts by determining the actions taken to prevent disease and the perceived benefits. Perception of barriers shows that adolescents can explain the obstacles in carrying out efforts to prevent HIV/AIDS through the impact that will occur when not making these efforts. Adolescents can explain the perception of vulnerability to the risk of HIV/AIDS, seriousness in dealing with HIV/AIDS, encouragement to act in efforts to prevent HIV/AIDS, and the benefits of HIV/AIDS prevention efforts and perceived obstacles when making these efforts.


2018 ◽  
Vol 34 (S1) ◽  
pp. 114-115
Author(s):  
John Wong ◽  
Stephanie Anne Co ◽  
Christine Ingrid Espinosa ◽  
Raoul Bermejo ◽  
Wilibald Zeck ◽  
...  

Introduction:The Philippines has an increasing number of newly diagnosed cases of human immunodeficiency virus and acquired immune deficiency syndrome (HIV/AIDS). In 2010, the Philippine National Health Insurance Corporation (PhilHealth) introduced an Outpatient HIV/AIDS Treatment (OHAT) package to cover the necessary basic healthcare expenses of patients. The objective of this study was to review patients’ perspectives on the OHAT package in terms of meeting health needs and providing economic risk protection.Methods:The study was divided into two phases: (i) patient surveys (PS); and (ii) health provider interviews (HPI). The PS focused on the health needs of package utilizers and non-utilizers, specifically their satisfaction with the current package coverage. The HPI focused on key personnel working at treatment hubs to gain insight on the impact of the OHAT package on facility operations, service delivery, and patient care.Results:The majority of patients were satisfied with the current package because of the reduced annual out-of-pocket (OOP) costs. However, continuing OOP expenditure was also the main reason for dissatisfaction. This was due to non-uniform provision of services across different hubs, mainly resulting from the unavailability of services and health provider discretion on final package inclusions. Non-coverage of opportunistic infection (OI) treatment and privacy issues were also noted as causes of dissatisfaction. Claim filing for formal membership requires an employer's signature for proof of contribution. Due to the fear of stigma some members created a second insurance account or shifted to an individual payment type, which increased OOP expenses.Conclusions:The OHAT package has increased access to services and medications for HIV/AIDS patients in the Philippines. Despite increasing package utilization there is still room to improve the package, especially with regard to addressing privacy needs and non-uniform package inclusions, and extending coverage to the treatment of OIs.


2021 ◽  
Vol 14 (1) ◽  
pp. 14-20
Author(s):  
Taufan Citra Darmawan

   Human Immunodeficiency Virus (HIV) and Acquired Immune Deficiency Syndrome (AIDS) in Indonesia are deadly infectious diseases. This disease will always be a problem at the national and global levels. The impact that often occurs, especially in children with HIV/AIDS, is psychological changes, namely stress. Efforts to overcome its disturbance are storytelling and music therapy. This research aims to apply storytelling and music therapy to reduce stress in children with HIV/AIDS.    This research method was a quasi-experiment with a research design involving 1 group (one group pre-post test), containing 30 respondents aged 6-10 years with HIV/AIDS by purposive sampling. The independent variable was storytelling and music therapy, while the dependent variable was stress levels. The instrument used Hamilton Anxiety Questionaire (HAM-A). The results of the study showed that 26 samples (86.7%) experienced decreased stress levels. Analysis of  Wilcoxon sign rank test obtained α=0.009, which means there was a difference before and after therapy.    The combination of music therapy and storytelling can be a better alternative in reducing stress in children – by considering age, environment, and children's emotions to have an optimal effect.


Author(s):  
Brenda Melles ◽  
Andrew B Leger ◽  
Leigha Covell

This paper explores the use of eportfolio to develop, demonstrate and promote core competencies in a Professional Master of Public Health (MPH) program at Queen’s University in Kingston, Ontario, Canada. Piloted in 2016, the MPH Competency eportfolio is described as a purposeful collection of electronic evidence that demonstrates learning and achievement in public health over time. The eportfolio was framed both as a reflective learning process and a showcase product to demonstrate skills and competencies to potential employers. The eportfolio was implemented using an available tool on Queen’s University’s Learning Management System. To understand the impact of the eportfolio, students responded to a questionnaire and participated in a focus group. Themes identified from the student responses were: eportfolio helped students integrate and reflect on their learning and experience. eportfolio helped students to position their professional identity and experience for employers. Students were more convinced of the value of eportfolio as a reflection tool than as a showcase product for a professional setting. Students were not convinced that employers will actually look at an eportfolio. The technology used in this study was limiting for students. Students were interested in using other established and more user-friendly platforms. The findings of this study will benefit any program or course of study seeking a means to help students integrate their learning and demonstrate their accomplishments, skills, and competencies. This paper addresses how to integrate eportfolio at the program level and also provides insight into the student experience of their use. Cet article explore l’emploi d’un eportfolio pour développer, démontrer et promouvoir les compétences de base offertes dans un programme de maîtrise professionnelle en santé publique à l’Université Queen’s, à Kingston, en Ontario, au Canada. Le programme pilote, un eportfolio des compétences pour la maîtrise en santé publique, a été lancé en 2016. On le décrit comme un recueil ciblé de preuves électroniques qui démontrent l’apprentissage et les réussites en santé publique au fil des ans. On dit également que le eportfolio est à la fois un processus d’apprentissage par la réflexion ainsi qu’un produit phare qui permet de démontrer les aptitudes et les compétences aux employeurs potentiels. Le eportfolio a été mis en oeuvre grâce aux outils disponibles dans le système de gestion de l’apprentissage de l’Université Queen’s. Afin de comprendre l’impact du eportfolio, les étudiants ont répondu à un questionnaire et ont participé à un groupe de discussion. Les thèmes identifiés à partir des réponses des étudiants sont les suivants : Le eportfolio a aidé les étudiants à intégrer leur apprentissage et leurs expériences et à y réfléchir. Le eportfolio a aidé les étudiants à positionner leur identité et leurs expériences professionnelles à l’intention des employeurs. Les étudiants étaient davantage convaincus de la valeur du eportfolio en tant qu’outil de réflexion plutôt qu’en tant que produit phare pour un milieu professionnel. Les étudiants n’étaient pas convaincus que les employeurs allaient réellement examiner un eportfolio. La technologie employée dans cette étude était limitative pour les étudiants. Les étudiants étaient intéressés à utiliser d’autres plate-formes établies et plus faciles à employer. Les résultats de cette étude seront utiles pour n’importe quel programme ou n’importe quel cours qui vise à trouver un moyen d’aider les étudiants à intégrer leur apprentissage et à démontrer leurs réussites, leurs aptitudes et leurs compétences. Cet article explique comment intégrer un eportfolio dans un programme et fournit également des renseignements sur l’expérience des étudiants qui l’ont utilisé.


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