scholarly journals Falls and potential therapeutic interventions among elderly and older adult patients with cancer: a systematic review

2021 ◽  
Vol 21 (4) ◽  
pp. 1776-83
Author(s):  
Walid Kamal Abdelbasset ◽  
Gopal Nambi ◽  
Shereen H Elsayed ◽  
Ahmad M Osailan ◽  
Marwa M Eid
Keyword(s):  
Risk Factors ◽  
Systematic Review ◽  
Older Adults ◽  
Cancer Survivors ◽  
Older Adult ◽  
Systematic Reviews ◽  
Clinical Studies ◽  
Adult Patients ◽  
Patients With Cancer ◽  
Incidence Risk

Objectives: The aim of this study was to perform a systematic review for previous publications that have assessed the incidence, risk factors, and favorable procedures to prevent and manage falls among cancer survivors of elderly and older adults. Materials: This systematic review was undertook using PubMed, SCOPUS, Web of Science, Medline, and Cochrane Database of clinical studies and systematic reviews to determine the incidence, risk factors, favorable inpatient and outpatient management, and non-pharmacological interventions for falls among elderly and older adult patients with cancer from 2010 to October, 2020. Results: After the comprehensive screening, clinical studies, meta-analysis, systematic reviews, and established guidelines were included in this review. Only 5 clinical studies (3 randomized and 2 single-arm studies), 5 systematic reviews, and 6 established guidelines were considered eligible. The five systematic reviews provide risk factors of falls and the 6 guidelines provide assessment & prevention modalities of falls, however, the 6 clinical studies provide the non-pharmacological intervention for falling among cancer survivors. Many factors associated are demonstrated among wide range of elderly individuals.Earlier falls were reliably listed as an important risk factor of falls in the two inpatient and outpatient environments including both general older people and geriatric cancer populations. Conclusions: This review concludes that the assessment of falls among older individuals with cancer is the most important way for determining who could need additional observation and treatment program. Health professions involving physical therapy and occupational therapy have an important function for promoting health well-being in elderly and older adults with cancer. Keywords: Cancer; falls; elderly; older adults, risk factors, intervention.

scholarly journals Incidence, risk factors and prognostic effect of imaging right ventricular involvement in patients with COVID-19: a dose–response analysis protocol for systematic review

BMJ Open ◽  
2021 ◽  
Vol 11 (5) ◽  
pp. e049866
Author(s):  
Chenghui Zhou ◽  
Baohui Lou ◽  
Hui Li ◽  
Xin Wang ◽  
Hushan Ao ◽  
...  
Keyword(s):  
Risk Factors ◽  
Systematic Review ◽  
Right Ventricular ◽  
Dose Response ◽  
Meta Analysis ◽  
Adult Patients ◽  
Sensitivity Analyses ◽  
Prognostic Effect ◽  
All Cause Mortality ◽  
Incidence Risk

IntroductionEmerging evidence has shown that COVID-19 infection may result in right ventricular (RV) disturbance and be associated with adverse clinical outcomes. The aim of this meta-analysis is to summarise the incidence, risk factors and the prognostic effect of imaging RV involvement in adult patients with COVID-19.MethodsA systematical search will be performed in PubMed, EMBase, ISI Knowledge via Web of Science and preprint databases (MedRxiv and BioRxiv) (until October 2021) to identify all cohort studies in adult patients with COVID-19. The primary outcome will be the incidence of RV involvement (dysfunction and/or dilation) assessed by echocardiography, CT or MRI. Secondary outcomes will include the risk factors for RV involvement and their association with all-cause mortality during hospitalisation. Additional outcomes will include the RV global or free wall longitudinal strain (RV-GLS or RV-FWLS), tricuspid annular plane systolic excursion (TAPSE), fractional area change (FAC) and RV diameter. Univariable or multivariable meta-regression and subgroup analyses will be performed for the study design and patient characteristics (especially acute or chronic pulmonary embolism and pulmonary hypertension). Sensitivity analyses will be used to assess the robustness of our results by removing each included study at one time to obtain and evaluate the remaining overall estimates of RV involvement incidence and related risk factors, association with all-cause mortality, and other RV parameters (RV-GLS or RV-FWLS, TAPSE, S’, FAC and RV diameter). Both linear and cubic spline regression models will be used to explore the dose–response relationship between different categories (>2) of RV involvement and the risk of mortality (OR or HR).Ethics and disseminationThere was no need for ethics approval for the systematic review protocol according to the Institutional Review Board/Independent Ethics Committee of Fuwai Hospital. This meta-analysis will be disseminated through a peer-reviewed journal for publication.PROSPERO registration numberCRD42021231689.

Surgical under-treatment of older adult patients with cancer: A systematic review and meta-analysis

2021 ◽  
Author(s):  
Abdul Qadr Akinoso-Imran ◽  
Michael O'Rorke ◽  
Frank Kee ◽  
Haydee Jordao ◽  
Gerard Walls ◽  
...  
Keyword(s):  
Systematic Review ◽  
Older Adult ◽  
Meta Analysis ◽  
Adult Patients ◽  
Patients With Cancer

Rate of cannabis use in older adults with cancer

2020 ◽  
pp. bmjspcare-2020-002384
Author(s):  
Sahana Rajasekhara ◽  
Diane G Portman ◽  
Young D Chang ◽  
Meghan F Haas ◽  
Anthony L Randich ◽  
...  
Keyword(s):  
Older Adults ◽  
Older Adult ◽  
Drug Testing ◽  
Performance Status ◽  
Total Sample ◽  
Clinic Visit ◽  
Cannabis Use ◽  
Adult Patients ◽  
Self Report ◽  
Patients With Cancer

ObjectivesOlder adults with cancer are increasingly inquiring about and using cannabis. Despite this, few studies have examined cannabis use in patients with cancer aged 65 years and older as a separate group and identified characteristics associated with use. The current study sought to determine the rate of cannabis use in older adult patients with cancer and to identify demographic and clinical correlates of use.MethodsWe conducted a retrospective review of patients with cancer referred for specialised symptom management between January 2014 and May 2017 who underwent routine urine drug testing for tetrahydrocannabinol as part of their initial clinic visit.ResultsApproximately 8% (n=24) of patients with cancer aged 65 years and older tested positive for tetrahydrocannabinol compared with 30% (n=51) of young adults and 21% (n=154) of adults. At the univariate level, more cannabis users had lower performance status than non-users (p=0.02, Fisher’s exact test). There were no other demographic and clinical characteristics significantly associated with cannabis use in older adults.ConclusionsOlder adult patients made up nearly 25% (n=301) of the total sample and had a rate of cannabis use of 8%. As one of the first studies to assess cannabis use via objective testing rather than self-report, this study adds significantly to the emerging literature on cannabis use in people aged 65 years and older. Findings suggest the rate of use in older adults living with cancer is higher than that among older adults in the general population.

scholarly journals Improving implementation of psychological interventions to older adult patients with cancer: Convening older adults, caregivers, providers, researchers

2018 ◽  
Vol 9 (5) ◽  
pp. 423-429 ◽  
Author(s):  
Kelly M. Trevino ◽  
Charlotte Healy ◽  
Peter Martin ◽  
Beverly Canin ◽  
Karl Pillemer ◽  
...  
Keyword(s):  
Older Adults ◽  
Older Adult ◽  
Adult Patients ◽  
Psychological Interventions ◽  
Patients With Cancer

scholarly journals Incidence of and risk factors for postoperative delirium in older adult patients undergoing noncardiac surgery: a prospective study

2020 ◽  
Vol 20 (1) ◽  
Author(s):  
Arissara Iamaroon ◽  
Titima Wongviriyawong ◽  
Patumporn Sura-arunsumrit ◽  
Nattikan Wiwatnodom ◽  
Nichakarn Rewuri ◽  
...  
Keyword(s):  
Risk Factors ◽  
Prospective Study ◽  
Older Adult ◽  
Postoperative Delirium ◽  
Noncardiac Surgery ◽  
Adult Patients ◽  
A Prospective Study

scholarly journals The prevalence of obesity in older adults in Iran: a systematic review and meta-analysis

2019 ◽  
Vol 19 (1) ◽  
Author(s):  
Aliakbar Vaisi-Raygani ◽  
Masoud Mohammadi ◽  
Rostam Jalali ◽  
Akram Ghobadi ◽  
Nader Salari
Keyword(s):  
Systematic Review ◽  
Older Adults ◽  
Older Adult ◽  
Meta Analysis ◽  
The Body ◽  
Obesity Prevalence ◽  
Analysis Software ◽  
Obesity And Overweight ◽  
Age Dependent ◽  
Prevalence Of Obesity

Abstract Background one of the most important age-dependent physiologic alterations in the body composition of older adult people is obesity and overweight, increasing the risk of cardiovascular disease and mortality rate. Objective The aim of the present study is to determine the prevalence of obesity in older adults in Iran. Methods The present study was conducted via meta-analysis and systematic review method, from March 2000 to October 2018. Subject-related literature was obtained via searches in ScienceDirect, Medline (PubMed), SID, Magiran, Scopus, and Google Scholar databases. Heterogeneity of studies was assessed using the I2 index, and data were analyzed by Comprehensive-Meta analysis software. Results In the assessment of 18 studies and 29,943 persons aged over 50 years, the prevalence of obesity in older adults of Iran was 21.4% (95%CI: 26.6–16.9%) based on the meta-analysis. The highest obesity prevalence was obtained in older adults of Babol (Amir Shahr) which was 44.2% (95%CI: 41.1–47.2%) in 2007, while the minimum obesity prevalence was found in older adults of Razavi Khorasan which was 11.3% (95%CI, 10–12.8%) in 2007. Further, as the sample size and the study year increased, the obesity prevalence diminished in older Iranian adults (p < 0.05). Conclusion This study suggests that the prevalence of obesity in the older adults of Iran is high. Accordingly, healthcare planners and politicians should consider effective and practical policies to reduce obesity in older adults.

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