scholarly journals Gender Differences in Somatic Symptoms and Current Suicidal Risk in Outpatients with Major Depressive Disorder

2016 ◽  
Vol 13 (6) ◽  
pp. 609 ◽  
Author(s):  
Hong Jin Jeon ◽  
Jong-Min Woo ◽  
Hyo-Jin Kim ◽  
Maurizio Fava ◽  
David Mischoulon ◽  
...  
Keyword(s):  
Gender Differences ◽  
Major Depressive Disorder ◽  
Depressive Disorder ◽  
Somatic Symptoms ◽  
Suicidal Risk ◽  
Major Depressive

Gender differences in major depressive disorder: somatic symptoms and quality of life

2009 ◽  
Vol 2 (3) ◽  
pp. 119-127 ◽  
Author(s):  
Dolores Saiz González ◽  
Mercedes Rodríguez ◽  
Carmen García ◽  
Rita Prietoc ◽  
Jerónimo Saiz-Ruiz
Keyword(s):  
Quality Of Life ◽  
Gender Differences ◽  
Major Depressive Disorder ◽  
Depressive Disorder ◽  
Somatic Symptoms ◽  
Major Depressive

Gender differences in major depressive disorder: Results from the Netherlands study of depression and anxiety

2014 ◽  
Vol 156 ◽  
pp. 156-163 ◽  
Author(s):  
Jérôme J.J. Schuch ◽  
Annelieke M. Roest ◽  
Willem A. Nolen ◽  
Brenda W.J.H. Penninx ◽  
Peter de Jonge
Keyword(s):  
Gender Differences ◽  
Major Depressive Disorder ◽  
The Netherlands ◽  
Depressive Disorder ◽  
Depression And Anxiety ◽  
Major Depressive

The sunshine induced placebo effect in major depressive disorder patients exhibits gender differences

2016 ◽  
Vol 33 (S1) ◽  
pp. S411-S412
Author(s):  
J. Gailledreau ◽  
B. Gailledreau ◽  
P. Desbonnet ◽  
P. Khalifa Soussan ◽  
N. Desbonnet ◽  
...  
Keyword(s):  
Gender Differences ◽  
Major Depressive Disorder ◽  
Depressive Disorder ◽  
Placebo Effect ◽  
Microsoft Excel ◽  
Major Depressive ◽  
Double Blind ◽  
Sunny Weather ◽  
Competing Interest ◽  
Variable Weather

RationaleSunshine increases placebo effect in major depressive disorder (MDD) patients (Gailledreau et al., 2015). Kokras et al. (2014) showed that sunshine induces different responses in female than male mice in preclinical models of depression.ObjectiveTo determine whetehr the sunshine induced placebo effect exhibits gender differences in human.Materiel and methodsData from 9 double-blind, randomized, placebo-controlled studies of antidepressants conducted by the French GICIPI network were reviewed. MADRS (5) or HAM-D 17 (4) were used as the main efficacy tool. For each patient, variation of scores (Delta MADRS/Delta HAM-D) between two consecutive visits were correlated with the average sunshine index observed at noon between these visits. Sunshine indexes were provided by Météo-France. Correlations were computed with Microsoft Excel.ResultsAnalysis of both genders (n = 52) showed no statistically significant (NS) correlation (r2 = 0.0064) between sunshine and score variations. Analysis of males (n = 8) failed to demonstrate any significant correlation in cloudy (< 1000 Joules/cm2), variable (1000–2000 Joules/cm2) or sunny (> 2000 Joules/cm2) weather. Analysis of females (n = 44) showed NS correlation as well for cloudy or variable weather (r2 = 0.0016), but a strong correlation was observed for females exposed to sunny weather: r2 = 0, 315, n = 20, P < 0.01. This correlation was even stronger in the subpopulation of females aged less than 50 years: r2 = 0.6398, n = 12, P < 0.001.DiscussionThe hypothesis underlying this correlation between sunshine index and variations of MADRS/HAMD scales will be discussed.ConclusionSunshine increases placebo effect in female patients aged less than 50. This insufficiently known effect may be responsible for failure of a number of double-blind, randomized, studies of antidepressant compounds.Disclosure of interestThe authors have not supplied their declaration of competing interest.

A simpler definition of major depressive disorder

2009 ◽  
Vol 40 (3) ◽  
pp. 451-457 ◽  
Author(s):  
M. Zimmerman ◽  
J. N. Galione ◽  
I. Chelminski ◽  
J. B. McGlinchey ◽  
D. Young ◽  
...  
Keyword(s):  
Major Depressive Disorder ◽  
Depressive Disorder ◽  
Somatic Symptoms ◽  
Structured Interview ◽  
Major Depressive ◽  
Medically Ill ◽  
Treatment Providers ◽  
Dsm Iv ◽  
Definition Of ◽  
High Level

BackgroundThe DSM-IV symptom criteria for major depressive disorder (MDD) are somewhat lengthy, with many studies showing that treatment providers have difficulty recalling all nine symptoms. Moreover, the criteria include somatic symptoms that are difficult to apply in patients with medical illnesses. In a previous report, we developed a briefer definition of MDD that was composed of the mood and cognitive symptoms of the DSM-IV criteria, and found high levels of agreement between the simplified and full DSM-IV definitions. The goal of the present study was to replicate these findings in another large sample of psychiatric out-patients and to extend the findings to other patient samples.MethodWe interviewed 1100 psychiatric out-patients and 210 pathological gamblers presenting for treatment and 1200 candidates for bariatric surgery. All patients were interviewed by a diagnostic rater who administered a semi-structured interview. We inquired about all symptoms of depression for all patients.ResultsIn all three samples high levels of agreement were found between the DSM-IV and the simpler definition of MDD. Summing across all 2510 patients, the level of agreement between the two definitions was 95.5% and the κ coefficient was 0.87.ConclusionsAfter eliminating the four somatic criteria from the DSM-IV definition of MDD, a high level of concordance was found between this simpler definition and the original DSM-IV classification. This new definition offers two advantages over the current DSM-IV definition – it is briefer and it is easier to apply with medically ill patients because it is free of somatic symptoms.

Anxiety and somatic symptoms as predictors of treatment-related adverse events in major depressive disorder

2004 ◽  
Vol 126 (3) ◽  
pp. 287-290 ◽  
Author(s):  
George I. Papakostas ◽  
Timothy Petersen ◽  
Megan E. Hughes ◽  
Andrew A. Nierenberg ◽  
Jonathan E. Alpert ◽  
...  
Keyword(s):  
Major Depressive Disorder ◽  
Adverse Events ◽  
Depressive Disorder ◽  
Somatic Symptoms ◽  
Major Depressive

The Impact of Somatic Symptoms on the Course of Major Depressive Disorder

2016 ◽  
Vol 85 ◽  
pp. 55
Author(s):  
E. Bekhuis ◽  
L. Boschloo ◽  
J.G.M. Rosmalen ◽  
M.K. de Boer ◽  
R.A. Schoevers
Keyword(s):  
Major Depressive Disorder ◽  
Depressive Disorder ◽  
Somatic Symptoms ◽  
Major Depressive ◽  
The Impact

Mirtazapine versus venlafaxine for the treatment of somatic symptoms associated with major depressive disorder: A randomized, open-labeled trial

2009 ◽  
Vol 169 (2) ◽  
pp. 118-123 ◽  
Author(s):  
Eun-Ho Kang ◽  
In-Soo Lee ◽  
Sang-Keun Chung ◽  
Sang-Yeol Lee ◽  
Eui-Jung Kim ◽  
...  
Keyword(s):  
Major Depressive Disorder ◽  
Depressive Disorder ◽  
Somatic Symptoms ◽  
Major Depressive
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