Investigation on the Alternations of Bovine Serum Albumin (BSA) Structures in the Hydrogen Peroxide Gas Plasma Low Temperature Sterilization, Ethylene Oxide Sterilization and Moist Heat Disinfection

2009 ◽  
Vol 79 (3) ◽  
pp. 95-101
Author(s):  
S. Takashima
Keyword(s):  
Hydrogen Peroxide ◽  
Low Temperature ◽  
Bovine Serum Albumin ◽  
Ethylene Oxide ◽  
Serum Albumin ◽  
Bovine Serum ◽  
Moist Heat ◽  
Gas Plasma ◽  
Ethylene Oxide Sterilization

Partitioning of Poly(ethylene oxide), Poly(ethylene imide), and Bovine Serum Albumin in Isobutyric Acid + Water

2008 ◽  
Vol 41 (3) ◽  
pp. 997-1008 ◽  
Author(s):  
Alexander I. Norman ◽  
Brittney A. Manvilla ◽  
Evan L. Frank ◽  
Justine N. Niamke ◽  
Grant D. Smith ◽  
...  
Keyword(s):  
Bovine Serum Albumin ◽  
Ethylene Oxide ◽  
Serum Albumin ◽  
Bovine Serum ◽  
Isobutyric Acid ◽  
Acid Water ◽  
Poly Ethylene Oxide ◽  
Poly Ethylene

Interactions of anionic surfactants with poly(ethylene oxide) and bovine serum albumin polymers: effect of the counterion hydrophobicity

1999 ◽  
Vol 147 (1-2) ◽  
pp. 89-105 ◽  
Author(s):  
Dino Zanette ◽  
Cláudio F Lima ◽  
Ângelo A Ruzza ◽  
Alexanders T.N Belarmino ◽  
Sônia de F. Santos ◽  
...  
Keyword(s):  
Bovine Serum Albumin ◽  
Ethylene Oxide ◽  
Serum Albumin ◽  
Bovine Serum ◽  
Anionic Surfactants ◽  
Poly Ethylene Oxide ◽  
Poly Ethylene

In-situ monitoring of etching of bovine serum albumin using low-temperature atmospheric plasma jet

2017 ◽  
Vol 392 ◽  
pp. 1049-1054 ◽  
Author(s):  
J. Kousal ◽  
A. Shelemin ◽  
O. Kylián ◽  
D. Slavínská ◽  
H. Biederman
Keyword(s):  
Low Temperature ◽  
Bovine Serum Albumin ◽  
Serum Albumin ◽  
Bovine Serum ◽  
Plasma Jet ◽  
Atmospheric Plasma ◽  
In Situ Monitoring

scholarly journals Decontamination of N95 masks for re-use employing 7 widely available sterilization methods

PLoS ONE ◽  
2020 ◽  
Vol 15 (12) ◽  
pp. e0243965 ◽  
Author(s):  
Anand Kumar ◽  
Samantha B. Kasloff ◽  
Anders Leung ◽  
Todd Cutts ◽  
James E. Strong ◽  
...  
Keyword(s):  
Health Care ◽  
Hydrogen Peroxide ◽  
Ethylene Oxide ◽  
Woven Fabric ◽  
Treatment Modalities ◽  
Moist Heat ◽  
Gas Plasma ◽  
Fit Testing ◽  
Ultraviolet C ◽  
Hospital Wards

The response to the COVID-19 epidemic is generating severe shortages of personal protective equipment around the world. In particular, the supply of N95 respirator masks has become severely depleted, with supplies having to be rationed and health care workers having to use masks for prolonged periods in many countries. We sought to test the ability of 7 different decontamination methods: autoclave treatment, ethylene oxide gassing (ETO), low temperature hydrogen peroxide gas plasma (LT-HPGP) treatment, vaporous hydrogen peroxide (VHP) exposure, peracetic acid dry fogging (PAF), ultraviolet C irradiation (UVCI) and moist heat (MH) treatment to decontaminate a variety of different N95 masks following experimental contamination with SARS-CoV-2 or vesicular stomatitis virus as a surrogate. In addition, we sought to determine whether masks would tolerate repeated cycles of decontamination while maintaining structural and functional integrity. All methods except for UVCI were effective in total elimination of viable virus from treated masks. We found that all respirator masks tolerated at least one cycle of all treatment modalities without structural or functional deterioration as assessed by fit testing; filtration efficiency testing results were mostly similar except that a single cycle of LT-HPGP was associated with failures in 3 of 6 masks assessed. VHP, PAF, UVCI, and MH were associated with preserved mask integrity to a minimum of 10 cycles by both fit and filtration testing. A similar result was shown with ethylene oxide gassing to the maximum 3 cycles tested. Pleated, layered non-woven fabric N95 masks retained integrity in fit testing for at least 10 cycles of autoclaving but the molded N95 masks failed after 1 cycle; filtration testing however was intact to 5 cycles for all masks. The successful application of autoclaving for layered, pleated masks may be of particular use to institutions globally due to the virtually universal accessibility of autoclaves in health care settings. Given the ability to modify widely available heating cabinets on hospital wards in well-resourced settings, the application of moist heat may allow local processing of N95 masks.

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