scholarly journals Percutaneous Liver Needle Biopsy Methods Can Be Safe and Effective in Patients with Viral Hepatitis

2017 ◽  
Vol 23 (3) ◽  
pp. 65-70
Author(s):  
Zehra KARACAER ◽  
Fatma YILMAZ KARADAĞ ◽  
Gül DURMUŞ ◽  
Hüseyin ÇİÇEK ◽  
Emine PARLAK ◽  
...  
Keyword(s):  
Viral Hepatitis ◽  
Needle Biopsy ◽  
Biopsy Methods ◽  
Liver Needle Biopsy

scholarly journals Multiplex transcriptional analysis of paraffin-embedded liver needle biopsy from patients with liver fibrosis

2012 ◽  
Vol 5 (1) ◽  
Author(s):  
Nicholas R Staten ◽  
Eric A Welsh ◽  
Kurex Sidik ◽  
Sandra A McDonald ◽  
Dawn R Dufield ◽  
...  
Keyword(s):  
Liver Fibrosis ◽  
Needle Biopsy ◽  
Transcriptional Analysis ◽  
Liver Needle Biopsy

scholarly journals Does Iron Concentration in a Liver Needle Biopsy Accurately Reflect Hepatic Iron Burden in β-Thalassemia?

2000 ◽  
Vol 46 (8) ◽  
pp. 1185-1188 ◽  
Author(s):  
Guido Crisponi ◽  
Rossano Ambu ◽  
Franco Cristiani ◽  
Gabriella Mancosu ◽  
Valeria Marina Nurchi ◽  
...  
Keyword(s):  
Needle Biopsy ◽  
Iron Concentration ◽  
Hepatic Iron ◽  
Liver Needle Biopsy

scholarly journals Patient-reported outcomes and safety in patients undergoing synovial biopsy: comparison of ultrasound-guided needle biopsy, ultrasound-guided portal and forceps and arthroscopic-guided synovial biopsy techniques in five centres across Europe

RMD Open ◽  
2018 ◽  
Vol 4 (2) ◽  
pp. e000799 ◽  
Author(s):  
Søren Andreas Just ◽  
Frances Humby ◽  
Hanne Lindegaard ◽  
Laurent Meric de Bellefon ◽  
Patrick Durez ◽  
...  
Keyword(s):  
Adverse Events ◽  
Corticosteroid Therapy ◽  
Needle Biopsy ◽  
Patient Reported Outcomes ◽  
Safety Data ◽  
Synovial Biopsy ◽  
Ultrasound Guided ◽  
Biopsy Procedure ◽  
Patient Reported ◽  
Biopsy Methods

BackgroundWe present a European multicenter study, comparing safety data and patient-reported outcomes (PRO) from patients undergoing synovial biopsy using ultrasound-guided needle biopsy (US-NB), ultrasound-guided portal and forceps (US-P&F) or arthroscopic-guided (AG) procedures.ObjectivesTo describe safety and PRO data on joint indices of pain, stiffness and swelling before and after biopsy, procedural discomfort, joint status compared with before biopsy and willingness to undergo a second biopsy for each technique and compare the three techniques. To evaluate the impact on PRO and safety data of corticosteroid therapy as part of the biopsy procedure and sequential biopsy procedures.MethodsData were collected on the day of biopsy and 7–14 days postprocedure. Joint pain, swelling and stiffness indices were recorded as 0–100  mm Visual Analogue Scale; qualitative outcome variables on five-point Likert scales. Groups were compared with linear regression, adjusting for disease activity, corticosteroid therapy and prebiopsy PRO value and accounting for repeated measurements.ResultsA total of 524 synovial biopsy procedures were documented (402 US-NB, 65 US-P&F and 57 AGSB). There were eight adverse events (1.5%) with no difference between biopsy methods (p=0.55). All PROs were improved 2  weeks postprocedure, and there were no differences in postbiopsy change in PROs between biopsy methods. Corticosteroid administration, whether intramuscular (n=62) or intra-articular (n=38), did not result in more adverse events (p=0.81) and was associated with reduction in postbiopsy swelling (p<0.01). Sequential biopsy procedures (n=103 patients) did not result in more adverse events (p=0.61) or worsening in PRO data.ConclusionOverall, our results do not suggest a significant difference in safety or patient tolerability between US-NB, US-P&F and AGSB sampling. Further, corticosteroid therapy as part of the biopsy procedure and sequential biopsies is safe and well tolerated in patients.

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