scholarly journals Cardiac Arrest After Status Epilepticus: Bupropion and Ecstasy Intoxication

2018 ◽  
Vol 16 (1) ◽  
pp. 41-43
Author(s):  
Zübeyde Tuba Duran ◽  
Pınar Karabacak ◽  
Kemal Yetiş Gülsoy ◽  
Hatice Akdu ◽  
Füsun Eroğlu
Keyword(s):  
Cardiac Arrest ◽  
Status Epilepticus ◽  
Ecstasy Intoxication

scholarly journals Neurologic outcome of postanoxic refractory status epilepticus after aggressive treatment

Neurology ◽  
2018 ◽  
Vol 91 (23) ◽  
pp. e2153-e2162 ◽  
Author(s):  
Simone Beretta ◽  
Anna Coppo ◽  
Elisa Bianchi ◽  
Clara Zanchi ◽  
Davide Carone ◽  
...  
Keyword(s):  
Cardiac Arrest ◽  
Status Epilepticus ◽  
Refractory Status Epilepticus ◽  
Neurologic Outcome ◽  
Low Flow ◽  
Prognostic Indicators ◽  
Prolonged Treatment ◽  
Periodic Pattern ◽  
Refractory Status ◽  
Eeg Pattern

ObjectiveTo investigate neurologic outcome of patients with cardiac arrest with refractory status epilepticus (RSE) treated with a standardized aggressive protocol with antiepileptic drugs and anesthetics compared to patients with other EEG patterns.MethodsIn the prospective cohort study, 166 consecutive patients with cardiac arrest in coma were stratified according to 4 independent EEG patterns (benign, RSE, generalized periodic discharges [GPDs], malignant nonepileptiform) and multimodal prognostic indicators. Primary outcomes were survival and cerebral performance category (CPC) at 6 months.ResultsRSE occurred in 36 patients (21.7%) and was treated with an aggressive standardized protocol as long as multimodal prognostic indicators were not unfavorable. RSE started after 3 ± 2.3 days after cardiac arrest and lasted 4.7 ± 4.3 days. A benign EEG pattern was recorded in 76 patients (45.8%); a periodic pattern (GPDs) was seen in 13 patients (7.8%); and a malignant nonepileptiform EEG pattern was recorded in 41 patients (24.7%). The 4 EEG patterns were highly associated with different prognostic indicators (low-flow time, clinical motor seizures, N20 responses, neuron-specific enolase, neuroimaging). Survival and good neurologic outcome (CPC 1 or 2) at 6 months were 72.4% and 71.1% for benign EEG pattern, 54.3% and 44.4% for RSE, 15.4% and 0% for GPDs, and 2.4% and 0% for malignant nonepileptiform EEG pattern, respectively.ConclusionsAggressive and prolonged treatment of RSE may be justified in patients with cardiac arrest with favorable multimodal prognostic indicators.

scholarly journals Cardiac Arrest in Patients Managed for Convulsive Status Epilepticus

2018 ◽  
Vol 46 (8) ◽  
pp. e751-e760 ◽  
Author(s):  
Stephane Legriel ◽  
Edouard Bresson ◽  
Nicolas Deye ◽  
David Grimaldi ◽  
Bertrand Sauneuf ◽  
...  
Keyword(s):  
Cardiac Arrest ◽  
Status Epilepticus ◽  
Convulsive Status Epilepticus

Ketamine infusion for refractory status epilepticus: A case report of cardiac arrest

2018 ◽  
Vol 47 ◽  
pp. 149-151 ◽  
Author(s):  
Lauren Koffman ◽  
Ho Yan Yiu ◽  
Salia Farrokh ◽  
John Lewin ◽  
Romergryko Geocadin ◽  
...  
Keyword(s):  
Cardiac Arrest ◽  
Case Report ◽  
Status Epilepticus ◽  
Refractory Status Epilepticus ◽  
Ketamine Infusion ◽  
Refractory Status

scholarly journals Super-Refractory Status Epilepticus Treated with High Dose Perampanel: Case Series and Review of the Literature

2019 ◽  
Vol 2019 ◽  
pp. 1-7
Author(s):  
Christopher R. Newey ◽  
Naresh Mullaguri ◽  
Stephen Hantus ◽  
Vineet Punia ◽  
Pravin George
Keyword(s):  
Cardiac Arrest ◽  
Status Epilepticus ◽  
Case Series ◽  
Refractory Status Epilepticus ◽  
Critically Ill Patient ◽  
Unknown Etiology ◽  
High Dose ◽  
The Novel ◽  
Refractory Status ◽  
Symptomatic Seizures

Introduction. Acute symptomatic seizures are frequent in the critically ill patient and can be difficult to treat. The novel anticonvulsant perampanel may be effective in the treatment of status epilepticus considering its mechanism of action of being an AMPA antagonist. We present four cases of super refractory status epilepticus treated with high dose perampanel. Method. Case report. Cases. Four patients were treated with perampanel for their refractory status epilepticus. One patient had new onset refractory status epilepticus of unknown etiology. Three other patients had status epilepticus as a result of their cardiac arrest. Two of the cardiac arrest patients had myoclonus. In all patients, the additional of perampanel resulted in a reduction of seizure burden without affecting hemodynamics or hepatic or renal function. Conclusion. Perampanel may be effective in the treatment of super-refractory status epilepticus of varying etiologies. A larger, prospective study is needed to further assess this therapy.

scholarly journals Cardiac arrest by inhalation of deodorant spray

2018 ◽  
pp. bcr-2018-224345 ◽  
Author(s):  
Kelvin Harvey Kramp ◽  
Mahdi Salih ◽  
Elsbeth Thomeer ◽  
Martin Gardien
Keyword(s):  
Cardiac Arrest ◽  
Case Report ◽  
Status Epilepticus ◽  
Drug Abuse ◽  
Cause Of Death ◽  
Fatal Outcome ◽  
Young Patients ◽  
Inhalant Abuse ◽  
Successful Resuscitation ◽  
Postanoxic Encephalopathy

Drug abuse by inhalation of volatile household product substances is uncommon, however, it can have devastating consequences. This case report describes the fatal outcome of deodorant inhalation by a 19-year-old patient in a detoxification clinic who developed a cardiac arrest after inhaling butane from a deodorant spray. Despite initial successful resuscitation, he developed a postanoxic encephalopathy with a status epilepticus resistant to extensive treatment. Inhalant abuse can be a cause of death in young patients.

Loss of Limb Following Intravenous Diazepam

PEDIATRICS ◽  
1974 ◽  
Vol 53 (1) ◽  
pp. 112-114
Author(s):  
Sanford Schneider ◽  
John W. Mace
Keyword(s):  
Cardiac Arrest ◽  
Status Epilepticus ◽  
Side Effects ◽  
Venous Thrombosis ◽  
Intravenous Administration ◽  
Seizure Activity ◽  
Significant Morbidity ◽  
Prolonged Seizure ◽  
Intravenous Diazepam

Since its introduction for the control of status epilepticus in 1965, parenterally administered diazepam has proven to be extremely effective in halting prolonged seizure activity. Reported side effects have been minimal and usually not associated with significant morbidity. However, apnea, bradycardia, hypotension, cardiac arrest, and conversion of atypical spike and wave status epilepticus to graudmal status have been reported. Additionally, thrombophlebitis following intravenous administration has been associated with diazepam. Langdon et al. recently stated that 3.5% of patients receiving diazepam intravenously Prior to esophagogastroscopy developed thrombophlebitis. In several patients venous thrombosis was marked and tender cords were palpable many months after injection.

Abstract 257: Combining the Initial Four B Score and Continuous EEG to Predict Survival After Cardiac Arrest

Circulation ◽  
2014 ◽  
Vol 130 (suppl_2) ◽  
Author(s):  
Chun Song Youn ◽  
Clifton W Callaway ◽  
Jon C Rittenberger
Keyword(s):  
Cardiac Arrest ◽  
Status Epilepticus ◽  
Hospital Discharge ◽  
Discharge Rate ◽  
Pupillary Light Reflex ◽  
Convulsive Status Epilepticus ◽  
Light Reflex ◽  
Pupillary Light ◽  
Continuous Eeg ◽  
Corneal Reflex

Background: Outcome prediction after cardiac arrest is a challenging problem and multiple tests should be performed to predict outcome accurately. We tested whether the combination of initial brainstem reflex examination (FOUR_B score) and continuous EEG were superior to either test alone for predicting survival after cardiac arrest. Methods: Review of consecutive patients receiving continuous EEG monitoring between April 2010 and June 2013. Patients were divided into three groups according to initial FOUR_B score; FOUR_B = 0-1, FOUR_B = 2 and FOUR_B = 4. A blinded rater dichotomized continuous EEG patterns during the first 48 hours into malignant patterns (non-convulsive status epilepticus, convulsive status epilepticus, myoclonic status epilepticus and generalized periodic epileptiform discharges). The primary outcome was survival to hospital discharge. Results: Of 380 subjects, 45 were excluded (44 missing initial FOUR_B score, 1 with age of 16 years). Mean (SD) age was 58 (17) and 208 (62.1%) subjects were male. Ventricular fibrillation was initial rhythm for 95 (28.4%) subjects. Survival to hospital discharge rate was 7.8% for FOUR_B 0-1, 32.0% for FOUR_B 2 and 51.9% for FOUR_B 4, respectively. Among subjects with malignant cEEG, survival to hospital discharge rate was 0% for FOUR_B 0-1, 8.1% for FOUR_B 2 and 12.5% for FOUR_B 4, respectively. All 42 subjects with no pupillary light reflex, no corneal reflex and malignant cEEG, had poor outcome (false positive rate 0; 95% CI, 0-7%). In the multivariate analysis, survival was independently associated with shockable rhythm (OR 5.76; 95% C.I. 2.88-11.54), FOUR_B 2 (OR 7.36; 95% C.I. 2.83-19.90), FOUR_B 4 (OR 8.99; 95% C.I. 3.58-22.56) and non-malignant cEEG (OR 19.91; 95% C.I. 6.44-61.51). Conclusion: Initial FOUR_B score and malignant cEEG pattern were independently associated with survival to hospital discharge. All subjects who have no pupillary light reflex, no corneal reflex and malignant cEEG did not survive to hospital discharge.

Prognostic value of electrographic postanoxic status epilepticus in comatose cardiac-arrest survivors in the therapeutic hypothermia era

Resuscitation ◽  
2013 ◽  
Vol 84 (3) ◽  
pp. 343-350 ◽  
Author(s):  
Stéphane Legriel ◽  
Julia Hilly-Ginoux ◽  
Matthieu Resche-Rigon ◽  
Sybille Merceron ◽  
Jeanne Pinoteau ◽  
...  
Keyword(s):  
Cardiac Arrest ◽  
Status Epilepticus ◽  
Therapeutic Hypothermia ◽  
Prognostic Value

Outcome following postanoxic status epilepticus in patients with targeted temperature management after cardiac arrest

2015 ◽  
Vol 49 ◽  
pp. 173-177 ◽  
Author(s):  
Irina Dragancea ◽  
Sofia Backman ◽  
Erik Westhall ◽  
Malin Rundgren ◽  
Hans Friberg ◽  
...  
Keyword(s):  
Cardiac Arrest ◽  
Status Epilepticus ◽  
Targeted Temperature Management ◽  
Temperature Management

EEG Artifact Versus Subclinical Status Epilepticus in a Patient Following Cardiac Arrest

2018 ◽  
Vol 29 (1) ◽  
pp. 110-112 ◽  
Author(s):  
Jean E. Cibula ◽  
Daniel S. Demos ◽  
Brenda G. Fahy
Keyword(s):  
Cardiac Arrest ◽  
Status Epilepticus
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