scholarly journals Screening Effects of Methanol Extracts of The Diplotaxis tenuifolia and Reseda lutea on The Enzymatic Antioxidant Defense Systems and Aldose Reductase Activity

2018 ◽  
Author(s):  
Naznoosh Shomali ◽  
Khalid Sharro Abdalrahman ◽  
Merve Gülşah Güneş ◽  
Belgin Sultan İşgör ◽  
Özlem Yıldırım
Keyword(s):  
Aldose Reductase ◽  
Antioxidant Defense ◽  
Reductase Activity ◽  
Enzymatic Antioxidant ◽  
Methanol Extracts ◽  
Defense Systems ◽  
Antioxidant Defense Systems

Antioxidant Defense Systems

2021 ◽  
pp. 94-143
Author(s):  
Carmen Cecilia Espíndola Díaz
Keyword(s):  
Antioxidant Defense ◽  
Defense Systems ◽  
Antioxidant Defense Systems

scholarly journals The Role of Oxidative Stress in Cardiac Disease: From Physiological Response to Injury Factor

2020 ◽  
Vol 2020 ◽  
pp. 1-29 ◽  
Author(s):  
Rossella D’Oria ◽  
Rossella Schipani ◽  
Anna Leonardini ◽  
Annalisa Natalicchio ◽  
Sebastio Perrini ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Myocardial Injury ◽  
Antioxidant Defense ◽  
Experimental Studies ◽  
Chemical Species ◽  
Oxygen Species ◽  
Molecular Abnormalities ◽  
Defense Systems ◽  
Antioxidant Defense Systems

Reactive oxygen species (ROS) are highly reactive chemical species containing oxygen, controlled by both enzymatic and nonenzymatic antioxidant defense systems. In the heart, ROS play an important role in cell homeostasis, by modulating cell proliferation, differentiation, and excitation-contraction coupling. Oxidative stress occurs when ROS production exceeds the buffering capacity of the antioxidant defense systems, leading to cellular and molecular abnormalities, ultimately resulting in cardiac dysfunction. In this review, we will discuss the physiological sources of ROS in the heart, the mechanisms of oxidative stress-related myocardial injury, and the implications of experimental studies and clinical trials with antioxidant therapies in cardiovascular diseases.

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