scholarly journals Anti-cancer and anti-inflamatory effects of Centaurea solstitialis extract on human cancer cell lines

2018 ◽  
Author(s):  
Mehlika Alper ◽  
Hatice Güneş
Keyword(s):  
Cell Lines ◽  
Cancer Cell ◽  
Human Cancer ◽  
Cancer Cell Lines ◽  
Centaurea Solstitialis ◽  
Human Cancer Cell ◽  
Human Cancer Cell Lines ◽  
Anti Cancer

The anti-cancer effect of amygdalin on human cancer cell lines

2019 ◽  
Vol 46 (2) ◽  
pp. 2059-2066 ◽  
Author(s):  
Asghar Arshi ◽  
Sayed Mostafa Hosseini ◽  
Fataneh Saleh Khaje Hosseini ◽  
Zahra Yousefnejad Amiri ◽  
Fatemeh Sadat Hosseini ◽  
...  
Keyword(s):  
Cell Lines ◽  
Cancer Cell ◽  
Human Cancer ◽  
Cancer Cell Lines ◽  
Human Cancer Cell ◽  
Human Cancer Cell Lines ◽  
Anti Cancer

Abstract 3797: Anti-cancer effects of novel imipridone DRD2 antagonists in a panel of human cancer cell lines

2020 ◽  
Author(s):  
Reine Hanna ◽  
Reem Daouk ◽  
Farah Ballout ◽  
Sarra El-Soussie ◽  
Jad Abdallah ◽  
...  
Keyword(s):  
Cell Lines ◽  
Cancer Cell ◽  
Human Cancer ◽  
Cancer Cell Lines ◽  
Human Cancer Cell ◽  
Human Cancer Cell Lines ◽  
Anti Cancer

Design, Synthesis and In vitro Cytotoxic Evaluation of Novel Hybrids of Artemisinin and Quinazolinone

2021 ◽  
Vol 18 ◽  
Author(s):  
Tran Khac Vu ◽  
Bach Xuan Nguyen ◽  
Linh Nguyen Pham Duy ◽  
Thuc Bao Nguyen Truong ◽  
Anh Tuan Phung ◽  
...  
Keyword(s):  
Cell Lines ◽  
Cancer Cell ◽  
Human Cancer ◽  
Cancer Cell Lines ◽  
Human Cancer Cell ◽  
Human Cancer Cell Lines ◽  
Anti Cancer ◽  
Ic50 Values ◽  
Mcf 7

Background: In this study, two novel hybrid series of artemisinin and quinazolinones were synthesized and evaluated in vitro cytotoxicity against two human cancer cell lines, including SKLu-1 (lung cancer), MCF- 7 (breast cancer). The bio-assay results indicated that most of the target compounds exhibited cytotoxic activities against both human cancer cell lines tested, and seemed to be more cytotoxic toward the breast (MCF-7) cancer cells than lung (SKLu-1) cancer cells. Among the synthesized artemisinin hybrids, the compound 13d containing a quinazolinone conjugated system exhibited the most potent cytotoxicity against the SKLu-1 and MCF-7 cell lines with IC50 values of 1.62 and 0.77 µM, respectively. Objective: This study aims at developing novel hybrids of artemisinin and quinazolinones as anti-cancer agents. Method: A series of novel hybrids were designed, synthesized and evaluated for cytotoxicity against two human cancer cell lines, including SKLu-1 and MCF-7 using SRB method. Results : All thirteen hybrids of artemisinin with quinazolinone exhibited cytotoxic activity against two tested cancer cell lines, in which the compound 13d exhibited the most potent cytotoxicity against the SKLu-1 and MCF-7 cell lines with IC50 values of 1.62 and 0.77 µM, respectively. Conclusion: The research results suggest that some compounds could be considered as leads for future design of hybrids and have the potential for further studies in the field of anti-cancer agent development.

Phosphonium Salt Displays Cytotoxic Effects Against Human Cancer Cell Lines

2018 ◽  
Vol 18 (5) ◽  
pp. 765-765
Author(s):  
Dhanyalayam D ◽  
Palma G ◽  
Cappello AR ◽  
Mariconda A ◽  
Sinicropi MS ◽  
...  
Keyword(s):  
Cell Lines ◽  
Cancer Cell ◽  
Medicinal Chemistry ◽  
Phosphonium Salt ◽  
Human Cancer ◽  
Cancer Cell Lines ◽  
Human Cancer Cell ◽  
Cytotoxic Effects ◽  
Human Cancer Cell Lines ◽  
Anti Cancer

Due to an oversight one of the author’s name was published wrong in the article entitled “Phosphonium Salt Displays Cytotoxic Effects Against Human Cancer Cell Lines” in “Anti-Cancer Agents in Medicinal Chemistry, 2015, Vol. 17, No. 13. pp. 1796.” <p> The correct names of all authors are given below: <p> Dhanyalayam D, Palma G, Cappello AR, Mariconda A, Sinicropi MS, Giordano F, Del Vecchio V, Ramunno A, Arra C, Longo P, Saturnino C.

scholarly journals Synthesis and anti-cancer activities of glycosides and glycoconjugates of diterpenoid isosteviol

MedChemComm ◽  
2019 ◽  
Vol 10 (8) ◽  
pp. 1488-1498 ◽  
Author(s):  
Radmila R. Sharipova ◽  
Mayya G. Belenok ◽  
Bulat F. Garifullin ◽  
Anastasiya S. Sapunova ◽  
Alexandra D. Voloshina ◽  
...  
Keyword(s):  
Cell Lines ◽  
Cancer Cell ◽  
Human Cancer ◽  
Cancer Cell Lines ◽  
Human Cancer Cell ◽  
Human Cancer Cell Lines ◽  
Anti Cancer ◽  
Mcf 7

A series of glycosides and glycoconjugates of diterpenoid isosteviol with various monosaccharide residues were synthesized. Most of them showed moderate to significant cytotoxicity against human cancer cell lines M-HeLa and MCF-7.

scholarly journals Synthesis and evaluation of a series of resveratrol analogues as potent anti-cancer agents that target tubulin

MedChemComm ◽  
2015 ◽  
Vol 6 (5) ◽  
pp. 788-794 ◽  
Author(s):  
Nikhil R. Madadi ◽  
Hongliang Zong ◽  
Amit Ketkar ◽  
Chen Zheng ◽  
Narsimha R. Penthala ◽  
...  
Keyword(s):  
Cell Lines ◽  
Cancer Cell ◽  
Human Cancer ◽  
Cancer Cell Lines ◽  
Human Cancer Cell ◽  
Anticancer Activities ◽  
Human Cancer Cell Lines ◽  
Anti Cancer ◽  
Resveratrol Analogues

Novel resveratrol analogues have been synthesized and evaluated for their anticancer activities against a panel of 60 human cancer cell lines.

scholarly journals Novel Chalcone Derivatives Show Anti‐Cancer Effects in Several Human Cancer Cell Lines

2015 ◽  
Vol 29 (S1) ◽  
Author(s):  
Tawna Whited ◽  
Bryce Adams ◽  
Christopher Stang ◽  
Thomas Pierson ◽  
Rahul Khupse ◽  
...  
Keyword(s):  
Cell Lines ◽  
Cancer Cell ◽  
Human Cancer ◽  
Cancer Cell Lines ◽  
Human Cancer Cell ◽  
Human Cancer Cell Lines ◽  
Chalcone Derivatives ◽  
Anti Cancer
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