scholarly journals Fundus Autofluorescence Changes in Age-related Maculopathy

2018 ◽  
Vol 48 (6) ◽  
pp. 304-308 ◽  
Author(s):  
Pınar Bingöl Kızıltunç ◽  
Figen Şermet
2021 ◽  
pp. bjophthalmol-2021-318820
Author(s):  
Riccardo Sacconi ◽  
Maria Brambati ◽  
Alexandra Miere ◽  
Eliana Costanzo ◽  
Vittorio Capuano ◽  
...  

AimTo characterise macular neovascularisation (MNV) developing in eyes affected by geographic atrophy (GA).MethodsIn this multicentric longitudinal study involving three retina referral centres, patients previously affected by GA who developed an active MNV were included. Patients were investigated using structural optical coherence tomography (OCT), fundus autofluorescence, OCT-angiography and dye angiographies. Patients were treated with ProReNata antivascular endothelial growth factor (VEGF) injections and were revaluated after treatment.ResultsAmong 512 patients previously diagnosed with GA, 40 eyes of 40 patients (mean age 80.8±7.9 years, mean GA area 8.73±7.39 mm2) presented with treatment-naïve exudative MNV (accounting for an estimated prevalence of 7.81%; 5.49 to 10.13, 95% CIs) and thus were included in the analysis. 67.5% of MNVs were classified as type 2 MNV, 25% as type 1, 2.5% as type 3 and 5% as mixed phenotype. In 92.5% of cases, active MNV in GA showed subretinal hyperreflective material with or without evidence of subretinal/intraretinal hyporeflective exudation. During a mean follow-up of 28±25 months, patients were treated with 6.6±6.3 anti-VEGF injections, with 2.9±1.4 injections in the first year of treatment. No patient developed GA enlargement in the area of MNV.ConclusionsMNVs in GA showed different features and therapeutic response in comparison to previously reported features of MNV in age-related macular degeneration (AMD) without GA. For these reasons, the combined phenotype (ie, GA with neovascular AMD) should be considered as a distinct entity in the research and clinical setting.


2012 ◽  
Vol 53 (4) ◽  
pp. 2193 ◽  
Author(s):  
Lukas Reznicek ◽  
Tamer Wasfy ◽  
Carmen Stumpf ◽  
Anselm Kampik ◽  
Michael Ulbig ◽  
...  

Author(s):  
Renata del Carmen Garcia Franco ◽  
Marlon Rafael Garcia Roa ◽  
Veronica Romero Morales ◽  
Miguel Angel Vazquez Membrillo ◽  
Ximena Mira Lorenzo ◽  
...  

2013 ◽  
Vol 97 (5) ◽  
pp. 622-626 ◽  
Author(s):  
Elisabetta Pilotto ◽  
Francesca Guidolin ◽  
Enrica Convento ◽  
Luigi Spedicato ◽  
Stela Vujosevic ◽  
...  

2017 ◽  
Vol 94 (2) ◽  
pp. 246-259 ◽  
Author(s):  
Angelica Ly ◽  
Lisa Nivison-Smith ◽  
Nagi Assaad ◽  
Michael Kalloniatis

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