scholarly journals The Effect of the Excisional Biopsy in the Detection of the Sentinel Lymph Node By Lymphoscintigraphy and Intraoperative Gamma Probe in Breast Cancer

2011 ◽  
Vol 20 (3) ◽  
pp. 100-103 ◽  
Author(s):  
Pelin Arıcan ◽  
İrfan Peksoy ◽  
Seniha Naldöken ◽  
Betül Bozkurt
Keyword(s):  
Breast Cancer ◽  
Lymph Node ◽  
Sentinel Lymph Node ◽  
Gamma Probe ◽  
Excisional Biopsy ◽  
Intraoperative Gamma Probe

Mapping Sentinel Lymph Node in Breast Cancer by Combined Lymphoscintigraphy, Blue-Dye, and Intraoperative Gamma-Probe

2000 ◽  
Vol 15 (3) ◽  
pp. 245-252 ◽  
Author(s):  
Giuliano Mariani ◽  
Giuseppe Villa ◽  
Marco Gipponi ◽  
Pietro Bianchi ◽  
Ferdinando Buffoni ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Lymph Node ◽  
Sentinel Lymph Node ◽  
Gamma Probe ◽  
Blue Dye ◽  
Intraoperative Gamma Probe

scholarly journals Preoperative Tumor Biopsy Results In More Detected Sentinel Node Than Intraoperative Biopsy In Breast Cancer Patients

2020 ◽  
Author(s):  
chenxi yuan ◽  
xinzhao wang ◽  
zhaoyun liu ◽  
chao li ◽  
mengxue bian ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Lymph Node ◽  
Sentinel Lymph Node ◽  
False Negative ◽  
False Negative Rate ◽  
Excisional Biopsy ◽  
Breast Cancer Surgery ◽  
Tumor Biopsy ◽  
Tracer Injection ◽  
Negative Rate

Abstract Background Sentinel lymph node biopsy (SLNB) acts as a vital role in the breast cancer surgery, and the identified number of sentinel nodes determines its accuracy to represent the status of axillae. There remain two tumor biopsy modes in breast cancer, preoperative and intraoperative biopsy. We compared the effect of the two different biopsies on the result of SLNB. Methods Patients with clinical stage T1-3, N0 tumor were enrolled in this study. 53% received preoperative tumor biopsy and 47% received intraoperative excisional biopsy. For search of the sentinel lymph node, patients received dual tracer injection. The number of SLNs detected and false negative rate were compared between groups. Results 204 patients were enrolled, 108 received preoperative tumor biopsy and 96 received intraoperative excisional biopsy. Among all the patients, 160 received ALND following SLNB. Preoperative tumor biopsy detected more SLNs than intraoperative biopsy (mean rank 113.87 vs. 90.9, p= 0.004). False negative rate in preoperative and intraoperative tumor biopsy was 3% and 18%, respectively. Conclusions Patients in preoperative tumor biopsy group could find more SLNs than intraoperative biopsy patients. False negative rate was also lower in preoperative biopsy group.

Dye- and gamma probe-guided sentinel lymph node biopsy in breast cancer patients: using patent blue dye and technetium-99m-labeled human serum albumin

Breast Cancer ◽  
2000 ◽  
Vol 7 (1) ◽  
pp. 87-94 ◽  
Author(s):  
Koichiro Tsugawa ◽  
Masakuni Noguchi ◽  
Koichi Miwa ◽  
Etsuro Bando ◽  
Kunihiko Yokoyama ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Lymph Node ◽  
Sentinel Lymph Node ◽  
Gamma Probe ◽  
Lymph Node Biopsy ◽  
Blue Dye ◽  
Breast Cancer Patients ◽  
Patent Blue ◽  
Node Biopsy ◽  
Patent Blue Dye

scholarly journals Preoperative Tumor Biopsy Results In More Detected Sentinel Nodes Than Intraoperative Biopsy In Breast Cancer Patients

2020 ◽  
Author(s):  
chenxi yuan ◽  
xinzhao wang ◽  
zhaoyun liu ◽  
chao li ◽  
mengxue bian ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Lymph Node ◽  
Sentinel Lymph Node ◽  
False Negative ◽  
False Negative Rate ◽  
Excisional Biopsy ◽  
Tumor Biopsy ◽  
Tracer Injection ◽  
Sentinel Nodes ◽  
Negative Rate

Abstract Background Sentinel lymph node biopsy (SLNB) acts as a vital role in the breast cancer surgery, and the identified number of sentinel nodes determines its accuracy to represent the status of axillae. There remain two tumor biopsy modes in breast cancer, preoperative and intraoperative biopsy. We compared the effect of the two different biopsies on the result of SLNB. Methods Patients with clinical stage T1-3, N0 tumor were enrolled in this study. 53% received preoperative tumor biopsy and 47% received intraoperative excisional biopsy. For search of the sentinel lymph node, patients received dual tracer injection. The number of SLNs detected and false negative rate were compared between groups. Results 204 patients were enrolled, 108 received preoperative tumor biopsy and 96 received intraoperative excisional biopsy. Among all the patients, 160 received ALND following SLNB. Preoperative tumor biopsy detected more SLNs than intraoperative biopsy (mean rank 113.87 vs. 90.9, p= 0.004). False negative rate in preoperative and intraoperative tumor biopsy was 3% and 18%, respectively. Conclusions Patients in preoperative tumor biopsy group could find more SLNs than intraoperative biopsy patients. False negative rate was also lower in preoperative biopsy group.

scholarly journals SENTINEL LYMPH NODE SCINTIGRAPHY IN BREAST CARCINOMA- COMPARISON OF TWO VERSUS FOUR INJECTION SITE TECHNIQUE

2017 ◽  
Vol 3 (1) ◽  
Author(s):  
Yasir Majeed ◽  
Saima Riaz ◽  
Muhammad Zulqarnain Chaudry ◽  
Muhammad Khalid Nawaz
Keyword(s):  
Breast Cancer ◽  
Lymph Node ◽  
Sentinel Lymph Node ◽  
Primary Tumour ◽  
Gamma Probe ◽  
Tier 1 ◽  
Group A ◽  
The Mean ◽  
Second Tier ◽  
Group B

Purpose: Sentinel lymph node (SLN) is the first regional node that drains lymph from the primary tumour and receives seeding of metastatic cells. Axillary node dissection remains the most reliable predictor of disease outcome. Controversies still exist about several aspects of lymphatic mapping and SLN biopsy for breast cancer, including number of radioisotope injection. The purpose of this study is to evaluate the success rate of different number of injection sites in the detection of SLN in breast cancer.Materials and Methods: A total of 120 consecutive breast cancer patients were divided into two groups. Group A (60 patients) received four intradermal periareolar (ID-PA) injections. Group B (60 patients) received two ID-PA injections.Imaging was carried out at 45 min post-injection. A gamma probe was used to explore the SLNs during surgery.Results: In Group A, 60 females with the mean age of 50.77 years were included in the study. 34 (56%) patients had single SLN. 25 (41.7%) had SLN with the second tier. 1 (1.7%) was negative. Group B included 60 patients (59 females and 1 male) with the mean age of 51.9 years. In 30 (50%) patients, single SLN was detected. 29 (48.3%) had SLN with the second tier. 1 (1.7%) was negative.Conclusion: SLN mapping with two periareolar ID injections carries less radiation dose and less pain as compared to the four injections with equal sensitivity for the visualization of SLNs.Key words: Breast cancer, intradermal injection, sentinel lymph node, Tc99 human serum albumin

Sentinel Lymph Node Analysis in Squamous Carcinoma of the Oral Cavity and Oropharynx

2002 ◽  
Vol 88 (3) ◽  
pp. S58-S60 ◽  
Author(s):  
A Pastore ◽  
GD Turetta ◽  
A Tarabini ◽  
D Turetta ◽  
L Feggi ◽  
...  
Keyword(s):  
Lymph Node ◽  
Sentinel Lymph Node ◽  
Oral Cavity ◽  
Neck Dissection ◽  
Clinical Evidence ◽  
Gamma Probe ◽  
Squamous Carcinoma ◽  
Neoplastic Lesion ◽  
Node Metastases ◽  
Intraoperative Gamma Probe

Aims The aim of our study was to evaluate the usefulness and applicability of sentinel lymph node (SLN) identification in NO carcinomas of the oral cavity and oropharynx. Study design We carried out a prospective evaluation of SLN identification in 20 patients with oral cavity or oropharynx carcinomas with no clinical evidence of lymph node metastases. Methods Peritumoral infiltration with technetium-99-labeled nanocolloid followed by lymphoscintigrapy was carried out approximately 18 hours prior to surgery. A vital dye was injected intraoperatively and the SLN was identified with the aid of a gamma probe. All patients underwent routine neck dissection. Results While multiple radioactive nodes were generally identified on lymphoscintigraphy, the number of nodes ranging from one to five with variable degrees of uptake, intraoperative gamma probe scanning allowed the identification of a single more radioactive lymph node in 19 of the 20 patients. In only one patient did this method lead to the identification of two equally highly radioactive SLNs, with no uptake in the remaining nodes. All SLNs were ipsilateral to the neoplastic lesion. In 15 cases the SLN was tumor negative and so were the remaining nodes obtained by comprehensive neck dissection. In five cases the SLN was the only lymph node containing micrometastasis among those obtained by dissection. There were no instances of node positivity not involving the SLN. Conclusions Sentinel lymph node identification in ENT surgery may indicate intraoperatively if node metastases are present, thereby avoiding overtreatment in a substantial proportion of patients with NO carcinomas of the oral cavity or oropharynx.

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