High-Risk Carotid Imaging Predicts ST-Segment Elevated Myocardial Infarction in Young Patients: A Cross-Sectional Study

2019 ◽  
Vol 0 (0) ◽  
pp. 0-0
Author(s):  
Mustafa Umut Somuncu ◽  
Huseyin Karakurt
2012 ◽  
Vol 19 (04) ◽  
pp. 442-445
Author(s):  
HAROON AZIZ KHAN BABAR ◽  
ZAHID RAFIQUE BUTT ◽  
JAMIL AHMAD

Objective: To assess the frequency of hyperhomocysteinemia in patients of first attack of ST-segment elevated myocardialinfarction under age of 40 years. Design: Cross sectional study. Period: December 2009 to June 2010. Setting: Ch. Pervaiz Elahi Institute ofCardiology, Multan. Material and methods: A total of 65 patients of acute myocardial infarction were included in the study on the basis of chestpain, ECG changes and increased cardiac enzyme. Results: A total of 65 patients fulfilled the inclusion criteria were included the study. Meanage was 35.68 years. Out of the 65 patients, 87.7% were male and 12.3% were female, 41.5% patients has increased homocysteine level while68.5% had normal homocysteine level. Conclusions: Plasma Hcy is an important risk factor for the development of the acute myocardialinfarction.


2018 ◽  
Vol 24 (8) ◽  
pp. 1358-1364
Author(s):  
Mustafa Umut Somuncu ◽  
Ali Riza Demir ◽  
Huseyin Karakurt ◽  
Nail Guven Serbest ◽  
Belma Kalayci ◽  
...  

The presence of carotid atherosclerosis accompanied by coronary artery disease is associated with poor prognosis. A subset of patients who take aspirin continue to have recurrent cardiovascular events, which may be due to aspirin resistance (AR). Also, carotid plaques may cause turbulent flow which in turn may lead to platelet activation and poor antiplatelet response. In our study, we aimed to show the prevalence of AR and its relationship between high-risk carotid images in young patients with ST-segment elevated myocardial infarction (STEMI). In our study, we included 112 patients younger than 45 years with STEMI. Aspirin response test was evaluated 1 hour after aspirin intake using multiplate platelet function analyzer, and carotid ultrasonography has been performed to determine carotid intima–media thickness (CIMT) and the presence of carotid plaque. We identified 30.3% AR in young patients with STEMI. Carotid intima–media thickness ( P = .002), carotid plaque ( P = .012), and high-risk carotid image ( P = .015) values are significantly high in patients who have AR. Independent of other risk factors, the presence of carotid plaque and being in the high-risk carotid group were associated with 3.7 times and 3.2 times increased odds for AR, respectively. In young patients with STEMI, physicians should be careful about AR, especially in patients who have carotid plaque and thicker CIMT.


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