Study on material basis of Mahuang Fuzi Xixin decoction for anti-inflammation and immune suppression based on combined method of serum pharmacochemistry and serum pharmacology

2015 ◽  
Keyword(s):  
Immune Suppression ◽  
Combined Method ◽  
Material Basis ◽  
Serum Pharmacology ◽  
Anti Inflammation

scholarly journals Insights into the Role and Interdependence of Oxidative Stress and Inflammation in Liver Diseases

2016 ◽  
Vol 2016 ◽  
pp. 1-21 ◽  
Author(s):  
Sha Li ◽  
Ming Hong ◽  
Hor-Yue Tan ◽  
Ning Wang ◽  
Yibin Feng
Keyword(s):  
Oxidative Stress ◽  
Liver Cancer ◽  
Immune Suppression ◽  
Liver Diseases ◽  
Herbal Medicines ◽  
Vicious Cycle ◽  
Hepatic Diseases ◽  
Pathological Conditions ◽  
New Directions ◽  
Anti Inflammation

The crucial roles of oxidative stress and inflammation in the development of hepatic diseases have been unraveled and emphasized for decades. From steatosis to fibrosis, cirrhosis and liver cancer, hepatic oxidative stress, and inflammation are sustained and participated in this pathological progressive process. Notably, increasing evidences showed that oxidative stress and inflammation are tightly related, which are regarded as essential partners that present simultaneously and interact with each other in various pathological conditions, creating a vicious cycle to aggravate the hepatic diseases. Clarifying the interaction of oxidative stress and inflammation is of great importance to provide new directions and targets for developing therapeutic intervention. Herein, this review is concerned with the regulation and interdependence of oxidative stress and inflammation in a variety of liver diseases. In addition to classical mediators and signaling, particular emphasis is placed upon immune suppression, a potential linkage of oxidative stress and inflammation, to provide new inspiration for the treatment of liver diseases. Furthermore, since antioxidation and anti-inflammation have been extensively attempted as the strategies for treatment of liver diseases, the application of herbal medicines and their derived compounds that protect liver from injury via regulating oxidative stress and inflammation collectively were reviewed and discussed.

scholarly journals Traditional Uses, Pharmacological Effects, and Molecular Mechanisms of Licorice in Potential Therapy of COVID-19

2021 ◽  
Vol 12 ◽  
Author(s):  
Qian-hui Zhang ◽  
Hao-zhou Huang ◽  
Min Qiu ◽  
Zhen-feng Wu ◽  
Zhan-chang Xin ◽  
...  
Keyword(s):  
Adjuvant Treatment ◽  
Molecular Mechanisms ◽  
Clinical Symptoms ◽  
Inflammatory Factors ◽  
Type I ◽  
Pharmacological Effects ◽  
Traditional Chinese Herbal Medicine ◽  
Global Challenge ◽  
Material Basis ◽  
Anti Inflammation

The current Coronavirus disease 2019 (COVID-19) pandemic has become a global challenge, and although vaccines have been developed, it is expected that mild to moderate patients will control their symptoms, especially in developing countries. Licorice, not only a food additive, but also a common traditional Chinese herbal medicine, which has several pharmacological effects, such as anti-inflammation, detoxification, antibacterial, antitussive, and immunomodulatory effects, especially in respiratory diseases. Since the outbreak of COVID-19, glycyrrhizin, glycyrrhizin diamine and glycyrrhizin extract have been widely studied and used in COVID-19 clinical trials. Therefore, it is a very interesting topic to explore the material basis, pharmacological characteristics and molecular mechanism of licorice in adjuvant treatment of COVID-19. In this paper, the material basis of licorice for the prevention and treatment of COVID-19 is deeply analyzed, and there are significant differences among different components in different pharmacological mechanisms. Glycyrrhizin and glycyrrhetinic acid inhibit the synthesis of inflammatory factors and inflammatory mediators by blocking the binding of ACE 2 to virus spike protein, and exert antiviral and antibacterial effects. Immune cells are stimulated by multiple targets and pathways to interfere with the pathogenesis of COVID-19. Liquiritin can prevent and cure COVID-19 by simulating type I interferon. It is suggested that licorice can exert its therapeutic advantage through multi-components and multi-targets. To sum up, licorice has the potential to adjuvant prevent and treat COVID-19. It not only plays a significant role in anti-inflammation and anti-ACE-2, but also significantly improves the clinical symptoms of fever, dry cough and shortness of breath, suggesting that licorice is expected to be a candidate drug for adjuvant treatment of patients with early / mild COVID-19.

Alkaloids constituents from the fruits of Piper nigrum L. and their anti-inflammation activity

Planta Medica ◽  
2015 ◽  
Vol 81 (11) ◽  
Author(s):  
BM Lee ◽  
NT Quynh Mai ◽  
JA Kim ◽  
BS Min
Keyword(s):  
Piper Nigrum ◽  
Anti Inflammation

From biorefineries to bioproducts: conversion of pretreated pulp from biorefining streams to lignocellulose nanofibers

TAPPI Journal ◽  
2019 ◽  
Vol 18 (4) ◽  
pp. 233-241
Author(s):  
CHENGGUI SUN ◽  
RICHARD CHANDRA ◽  
YAMAN BOLUK
Keyword(s):  
Energy Consumption ◽  
Enzymatic Hydrolysis ◽  
Rheological Behavior ◽  
Material Basis ◽  
Softwood Pulp ◽  
Energy Consumptions ◽  
Hardwood Pulp ◽  
The Stability ◽  
Lignocellulose Nanofibers

This study investigates the use of pretreatment and enzymatic hydrolysis side streams and conversion to lignocellulose nanofibers. We used a steam-exploded and partial enzymatic hydrolyzed hardwood pulp and an organosolv pretreated softwood pulp to prepare lignocellulose nanofibers (LCNF) via microfluidization. The energies applied on fibrillation were estimated to examine the energy consumption levels of LCNF production. The energy consumptions of the fibrillation processes of the hardwood LCNF production and the softwood LCNF production were about 7040-14080 kWh/ton and 4640 kWh/ton on a dry material basis, respectively. The morphology and dimension of developed hardwood and softwood LCNFs and the stability and rheological behavior of their suspensions were investigated and are discussed.

The Life of Rural Scenery

Romanticism ◽  
2020 ◽  
Vol 26 (2) ◽  
pp. 191-201
Author(s):  
Paul Chirico
Keyword(s):  
Natural World ◽  
Abstract Concept ◽  
John Clare ◽  
Material Basis ◽  
The Moment

John Clare observed and described the natural world with an unsurpassed accuracy and intimacy. But his landscapes also bore the memories of life and labour. Like Wordsworth, he sought to create textual objects in transmissible forms, to deliver their reported worlds – expansive, dynamic, somehow inhabitable – to distant readers, drawing them into sympathetic intercommunion with a complex living scene. His intimate descriptive poetry reveals the tangible qualities of light and sound, and the material basis of the apparently abstract concept of time. Memory and imagination are understood to inhabit bodily spaces, provoking ‘real transport’: an observer lost in – and to – the moment. From his place and time, Clare felt solidarity with isolated birds, alienation from labour, estrangement from human communities. Publications such as annuals often showcased formulaic reflections on nature and on memory; Clare exploited textual duplicability, his meditative descriptive poetry spanning the history and futurity of an observed scene.

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