Novel method for dynamic monitoring and early-warning on wild resources of traditional Chinese medicines based on price ratio between drug and foodstuff

Author(s):  
WANG Jiabo
2021 ◽  
Vol 245 ◽  
pp. 01059
Author(s):  
Qian Gao ◽  
Yuchun Han ◽  
Junyi Yang ◽  
Guiqin Zhang ◽  
Yu Hong ◽  
...  

In order to strengthen the all-round and whole process management and control of the project, improve the quality of statistical data, support the high-quality development of the company and power grid, and identify the mismatch between the progress of fund payment and the progress of project site construction and cost accounting. Through the research on the dynamic monitoring and early warning model of power grid infrastructure project funds, the problems existing in the fund settlement and payment management of power grid project in the process of project implementation are accurately revealed, and the project fund payment risk is prevented.


2021 ◽  
Vol 3 ◽  
pp. e10
Author(s):  
Xiaohong Song ◽  
Anyi Zhao ◽  
Yan Liu ◽  
Jintang Cheng ◽  
Sha Chen ◽  
...  

Background Quantitative analysis of the active ingredients of Traditional Chinese Medicine is a research tendency. The objective of this study was to build a novel method, namely, Detection-confirmation-standardization-quantification (DCSQ), for the quantitative analysis of active components in traditional Chinese medicines, without individual reference standard. Methods Danshen (the dried root of Radix Salvia miltiorrhiza) was used as the matrix. The “extraction” function in high-performance liquid chromatography-mass (HPLC-MS) instrument was used to find the peaks corresponding to cryptotanshinone, tanshinone I, and tanshinone IIA in the total ion current (TIC) chromatogram of Danshen. The multicomponent reference standard (MCRS) containing the three tanshinones mainly was prepared by preparative HPLC. The contents of them in the resulting MCRS were determined by NMR; moreover, the constituents of the MCRS were confirmed. The MCRS containing known content of the three tanshinones was used as the reference standard for the quantitative analysis of cryptotanshinone, tanshinone I and tanshinone IIA in Danshen Samples by analytical HPLC. Results The optimized HPLC conditions for the quantitative analysis of the active components in Danshen were established, and the assignments of the extracted peaks were confirmed by analyzing the characteristic fragments in their MS/MS product ion spectra and UV spectra. Then, the MCRS containing the three tanshinones were successfully prepared. The results of determination about the contents by NMR showed linearity fitted with high likelihood and calibration curves possessed high linearity. The results of determination on Danshen Samples obtained through DCSQ exhibited minimal deviations, in contrast to those obtained through individual reference standards. Conclusion The establishing DCSQ is independent and convenient for the quantitative analysis of the active components in TCMs by MCRS, without individual reference standard. This method is a great advance in quantitative analysis for complex composition, especially TCMs.


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