scholarly journals JUNB (jun B proto-oncogene)

Author(s):  
F Chen
Keyword(s):  
1991 ◽  
Vol 129 (2) ◽  
pp. 221-224 ◽  
Author(s):  
Thomas Herdegen ◽  
Thomas R. Tölle ◽  
Rodrigo Bravo ◽  
Walter Zieglgänsberger ◽  
Manfred Zimmermann
Keyword(s):  

1995 ◽  
Vol 30 (2) ◽  
pp. 393-396 ◽  
Author(s):  
M. Dragunow ◽  
N. Butterworth ◽  
H. Waldvogel ◽  
R.L.M. Faull ◽  
L.F.B. Nicholson
Keyword(s):  

1991 ◽  
Vol 97 (2) ◽  
pp. 349-353 ◽  
Author(s):  
Douglas T Yamanishi ◽  
Julie A Buckmeier ◽  
Frank L Meyskens
Keyword(s):  

Endocrinology ◽  
2006 ◽  
Vol 147 (11) ◽  
pp. 5052-5060 ◽  
Author(s):  
Natalia Sinitskaya ◽  
Anthony Salingre ◽  
Paul Klosen ◽  
Florent G. Revel ◽  
Paul Pévet ◽  
...  

Species differences have been reported for the nighttime regulation of arylalkylamine N-acetyltransferase (AA-NAT), the melatonin rhythm-generating enzyme. In particular, de novo synthesis of stimulatory transcription factors is required for Aa-nat transcription in the Syrian hamster but not in the rat pineal gland. The present work investigated the contribution of phosphorylated cAMP-responsive element-binding protein, c-FOS, c-JUN, and JUN-B in the regulation of Aa-nat transcription in Syrian hamsters compared with rats. The nighttime pattern of cAMP-responsive element-binding protein phosphorylation and regulation by norepinephrine observed in the Syrian hamster was similar to those reported in the rat. On the contrary, strong divergences in c-FOS, c-JUN, and JUN-B expression were observed between both species. In Syrian hamster, predominant expression of c-FOS and c-JUN was observed at the beginning of night, whereas a predominant expression of c-JUN and JUN-B was observed in the late night in rat. The early peak of c-FOS and c-JUN, known to form a stimulatory transcription dimer, suggests that they are involved in the nighttime stimulation of Aa-nat transcription. Indeed, early-night administration of a protein synthesis inhibitor (cycloheximide) markedly decreased AA-NAT mRNA levels in Syrian hamster. In the rat, high levels of JUN-B and c-JUN, constituting an inhibitory transcription dimer, are probably involved in the late-night inhibition of Aa-nat transcription. Early-night administration of cycloheximide actually increased AA-NAT mRNA levels toward the late night. Therefore, composition and timing of the pineal activator protein-1 complexes differ between rat and Syrian hamster and may be an activator (Syrian hamster) or an inhibitor (rat) of Aa-nat transcription.


Diabetes ◽  
1993 ◽  
Vol 42 (4) ◽  
pp. 626-630 ◽  
Author(s):  
M. C. Honeyman ◽  
D. S. Cram ◽  
L. C. Harrison

1995 ◽  
Vol 24 (sup101) ◽  
pp. 121-125 ◽  
Author(s):  
R. W. Kinne ◽  
S. Boehm ◽  
T. Iftner ◽  
T. Aigner ◽  
S. Vornehm ◽  
...  
Keyword(s):  

2004 ◽  
Vol 49 (5) ◽  
pp. 468-474
Author(s):  
乔 吴 ◽  
亚 曹 ◽  
晓曦 陈 ◽  
永光 陶 ◽  
米丹 艾 ◽  
...  
Keyword(s):  

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