scholarly journals Mechanical Properties and Antibacterial Efficacy of Chitosan Films

2006 ◽  
Vol 11 (1) ◽  
pp. 27-36 ◽  
Author(s):  
TERUO NAKASHIMA ◽  
MASARU MATSUO ◽  
YUEZHEN BIN ◽  
YUMIKO NAKANO ◽  
TOMONORI KOBAYASHI ◽  
...  
Keyword(s):  
Mechanical Properties ◽  
Antibacterial Efficacy ◽  
Chitosan Films

scholarly journals Understanding the Barrier and Mechanical Behavior of Different Nanofillers in Chitosan Films for Food Packaging

Polymers ◽  
2021 ◽  
Vol 13 (5) ◽  
pp. 721 ◽  
Author(s):  
João Pires ◽  
Camila Damásio de Paula ◽  
Victor Gomes Lauriano Souza ◽  
Ana Luísa Fernando ◽  
Isabel Coelhoso
Keyword(s):  
Mechanical Properties ◽  
Mechanical Behavior ◽  
Food Packaging ◽  
Scientific Research ◽  
Barrier Properties ◽  
Plastic Pollution ◽  
Functional Attributes ◽  
Chitosan Films ◽  
Commercial Applications ◽  
Innovative Techniques

The continuous petroleum-based plastics manufacturing generates disposal issues, spreading the problem of plastic pollution and its rise in the environment. Recently, innovative techniques and scientific research promoted biopolymers as the primary alternative for traditional plastics, raising and expanding global bioplastic production. Due to its unmatched biological and functional attributes, chitosan (Ch) has been substantially explored and employed as a biopolymeric matrix. Nevertheless, the hydrophilicity and the weak mechanical properties associated with this biopolymer represent a significant intrinsic restriction to its implementation into some commercial applications, namely, in food packaging industries. Distinct methodologies have been utilized to upgrade the mechanical and barrier properties of Ch, such as using organic or inorganic nanofillers, crosslinkers, or blends with other polymers. This review intends to analyze the most recent works that combine the action of different nanoparticle types with Ch films to reinforce their mechanical and barrier properties.

Biocompatibility and mechanical properties evaluation of chitosan films containing an N-acylhydrazonic derivative

2020 ◽  
Vol 155 ◽  
pp. 105547 ◽  
Author(s):  
Davidson M.S. Wanderley ◽  
Demis F. Melo ◽  
Laryssa M. Silva ◽  
José W.L. Souza ◽  
Hermano V. Pina ◽  
...  
Keyword(s):  
Mechanical Properties ◽  
Chitosan Films

Improvement of the mechanical properties of chitosan films by the addition of poly(ethylene oxide)

2000 ◽  
Vol 40 (5) ◽  
pp. 1211-1215 ◽  
Author(s):  
V. L. Alexeev ◽  
E. A. Kelberg ◽  
G. A. Evmenenko ◽  
S. V. Bronnikov
Keyword(s):  
Mechanical Properties ◽  
Ethylene Oxide ◽  
Poly Ethylene Oxide ◽  
Chitosan Films ◽  
Poly Ethylene

Improved mechanical, physical and biological properties of chitosan films using Aloe vera and electrospun PVA nanofibers for wound dressing applications

2019 ◽  
pp. 152808371986693 ◽  
Author(s):  
Shirin Rafieian ◽  
Hamid Mahdavi ◽  
Mir Esmaeil Masoumi
Keyword(s):  
Mechanical Properties ◽  
Wound Dressing ◽  
Aloe Vera ◽  
Composite Layer ◽  
Synthetic Polymers ◽  
Biological Properties ◽  
Vapor Permeability ◽  
Natural Polymers ◽  
Simple Method ◽  
Chitosan Films

Natural polymers such as chitosan and Aloe vera are widely used in novel wound dressings due to their biocompatibility and biodegradability. A problem associated with these polymers is their poor mechanical behavior. Efforts have been made to improve the mechanical properties by mixing synthetic polymers such as PVA, but the role of chitosan and Aloe vera in the final dressing is dimmed. The techniques are also time-consuming and costly and there is still a need for an acceptable and affordable wound dressing which can be made through easily accessible techniques. A new but very simple method is introduced in this work for incorporating PVA nanofibers with Aloe vera-containing chitosan films. Using this method the levels of Aloe vera and chitosan in the system can be optimized at higher scales while benefiting from PVA best mechanical properties as a composite layer. Higher amounts of Aloe vera and chitosan in the system lead to lower product costs and more biocompability. The biological properties of films were examined through cell cytotoxicity and antibacterial tests and compared with Atomic force microscopy results. Physical and mechanical properties of films containing PVA nanofibers were characterized by water vapor permeability, swelling ratio, and tensile tests. The morphology of fibers before and after applying on the films was also observed by scanning electron microscopy. According to the results, this combination of natural and synthetic polymers has led to an affordable, biocompatible, and flexible film for wound dressing applications.

Biological Properties of Chitosan/Collagen Composites

2013 ◽  
Vol 587 ◽  
pp. 205-210 ◽  
Author(s):  
Alina Sionkowska ◽  
Beata Kaczmarek ◽  
J. Stalinska ◽  
A.M. Osyczka
Keyword(s):  
Mechanical Properties ◽  
Thermal Analysis ◽  
Alkaline Phosphatase ◽  
Human Mesenchymal Stem Cells ◽  
Biological Properties ◽  
Cellular Activity ◽  
New Materials ◽  
Sem Images ◽  
Biological Compatibility ◽  
Chitosan Films

The properties of new materials based on the blends of collagen and chitosan were studied along with their biological compatibility. Mechanical properties, thermal analysis, FTIR spectra and SEM images were obtained for different blends of chitosan/collagen in weight ratios 75/25, 50/50, 25/75. The materials in the form of 2D sheets were then subjected to cultures of human mesenchymal stem cells (hMSC) directed toward osteogenesis with ascorbate-2-phosphate and dexamethasone. The results showed that specified amounts of components influence the mechanical properties of obtained materials. Proliferation of hMSC decreased with increasing amounts of chitosan in collagen/chitosan films. However, the cellular activity of alkaline phosphatase (ALP), a marker of preosteoblasts and active osteoblasts, for plain collagen films ALP was the highest, whereas different ratios of collagen in chitosan/collagen composites had no effect on overall good ALP activity of hMSC. Based on the presented data, we believe the obtained materials are suitable for bone tissue engineering strategies.

Ageing of chitosan films: Effect of storage time on structure and optical, barrier and mechanical properties

2015 ◽  
Vol 66 ◽  
pp. 170-179 ◽  
Author(s):  
I. Leceta ◽  
M. Peñalba ◽  
P. Arana ◽  
P. Guerrero ◽  
K. de la Caba
Keyword(s):  
Mechanical Properties ◽  
Storage Time ◽  
Optical Barrier ◽  
Chitosan Films

scholarly journals Design and Development of Antibacterial/Anti-inflammatory Dual Drug-Loaded Nanofibrous Inserts for Ophthalmic Sustained Delivery of Gentamicin and Methylprednisolone: In Vitro Bioassay, Solvent, and Method Effects’ Evaluation

2021 ◽  
Author(s):  
Shahla Mirzaeei ◽  
Donya Barfar
Keyword(s):  
Mechanical Properties ◽  
Sustained Release ◽  
In Vitro Release ◽  
Core Shell ◽  
Solvent Mixtures ◽  
Antibacterial Efficacy ◽  
Electrospinning Technique ◽  
Dual Drug ◽  
Release Profiles

Purpose: To overcome the challenges caused by the use of conventional ophthalmic dosage forms such as the fast elimination of the drug from the surface of the eye, in this study, dual drug-loaded nanofibers were developed for sustained ophthalmic delivery of Gentamicin (GNT) and Methylprednisolone (MP). Moreover, the solvent effects, polymer mixtures, and method of preparation on the release profile of the prepared nanofibers, were evaluated. Methods: The nanofibers were prepared using Polycaprolactone, Poly (lactic-co-glycolic acid), and Polyvinyl alcohol using electrospinning technique. Thereafter, seven optimized formulations were developed with different solvent mixtures and polymer concentrations using various electrospinning methods. The physicochemical and mechanical properties of nanofibers were also evaluated, and the morphology of formulations was observed. The antibacterial efficacy was investigated and the in vitro release amounts of GNT and MP from nanofibers were estimated using the bioassay and Ultraviolet-visible spectroscopy. Results: The developed G1, G4, G5, G6, and G7 had suitable mechanical properties and morphologies with diameter ranging between 70-350 nm. The 1:1 v/v ratio of DMF/DCM in the solvent mixture and using core-shell technique for the preparation, formed nanofibers with more favorable release profiles. The optimized formulations indicated sustained-release manner for both drugs during 3-9 days and the antibacterial efficacy against Staphylococcus aureus. Conclusion: Among all the prepared formulations, the nanofiber with core-shell structure possessed the best sustained-release profiles of GNT and MP. The obtained results suggest that these nanofibers have a potential to be used as an insert in the eye for long-term release of the drug.

Mechanical properties, thermal stability, and solubility of sheep bone collagen–chitosan films

2019 ◽  
Vol 43 (1) ◽  
Author(s):  
Chengli Hou ◽  
Lingling Gao ◽  
Zhenyu Wang ◽  
Weili Rao ◽  
Manting Du ◽  
...  
Keyword(s):  
Mechanical Properties ◽  
Thermal Stability ◽  
Bone Collagen ◽  
Chitosan Films
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