scholarly journals All-Day Occlusion Therapy Using Stepwise Increasing Occluder for Patients with Anisometropic Amblyopia.

1994 ◽  
Vol 22 ◽  
pp. 78-82
Author(s):  
Chisato IGARASHI ◽  
Megumi TOMONARI ◽  
Nobuko SAISHO ◽  
Kuniko SUGITANI
Keyword(s):  
Anisometropic Amblyopia ◽  
Occlusion Therapy

scholarly journals Reversal of myopic Anisometropic amblyopia with occlusion therapy in a 25 year old

2014 ◽  
Vol 48 (1) ◽  
pp. 54 ◽  
Author(s):  
E Megbelayin ◽  
SM Ekpenyong ◽  
J Azunobi ◽  
G Ejiro
Keyword(s):  
Anisometropic Amblyopia ◽  
Occlusion Therapy

scholarly journals Can ocular dominance plasticity provide a general index to visual plasticity to personalize treatment in amblyopia?

2020 ◽  
Author(s):  
Chunwen Tao ◽  
Zhifen He ◽  
Yiya Chen ◽  
Jiawei Zhou ◽  
Robert F. Hess
Keyword(s):  
Visual Acuity ◽  
Cortical Plasticity ◽  
Ocular Dominance ◽  
Monocular Deprivation ◽  
Homeostatic Plasticity ◽  
Ocular Dominance Plasticity ◽  
Anisometropic Amblyopia ◽  
Occlusion Therapy ◽  
General Index ◽  
Before And After

AbstractPurposeRecently, Lunghi et al showed that amblyopic eye’s visual acuity per se after 2 months of occlusion therapy could be predicted by a homeostatic plasticity, i.e., the temporary shift of ocular dominance observed after a 2-hour monocular deprivation, in children with anisometropic amblyopia(Lunghi et al., 2016). In this study, we assess whether the visual acuity improvement of the amblyopic eye measured after 2 months of occlusion therapy could be predicted by this plasticity.MethodsSeven children (6.86 ± 1.46 years old; SD) with anisometropic amblyopia participated in this study. All patients were newly diagnosed and had no treatment history before participating in our study. They had finished 2 months of refractive adaptation and then received a 4-hour daily fellow eye patching therapy with an opaque patch for a 2-month period. Best-corrected visual acuity of the amblyopic eye was measured before and after the patching therapy. The homeostatic plasticity was assessed by measuring the temporary shift of ocular dominance observed after 2 hours of occlusion for the amblyopic eye before the treatment started. A binocular phase combination paradigm was used for this test.ResultsWe found that there was no significant correlation between the temporary shift of ocular dominance observed after 2 hours of occlusion for the amblyopic eye before the treatment started and the visual acuity gain obtained by the amblyopic eye from 2-month of classical patching therapy. This result involving the short-term patching of the amblyopic eye is consistent with a reanalysis of Lunghi et al’ s data.ConclusionsOcular dominance plasticity does not provide an index of cortical plasticity in the general sense such that it could be used to predict acuity outcomes from longer term classical patching.

scholarly journals Evaluation of the efficacy, safety, and stability of posterior chamber phakic intraocular lenses for correcting intractable myopic anisometropic amblyopia in a pediatric cohort

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Fathy Fawzy Morkos ◽  
Nader F. Fawzy ◽  
Mohamed El Bahrawy ◽  
Nada Fathy ◽  
Rania Serag Elkitkat
Keyword(s):  
Visual Acuity ◽  
Conventional Therapy ◽  
Case Series ◽  
Intraocular Lenses ◽  
Posterior Chamber ◽  
Anisometropic Amblyopia ◽  
Occlusion Therapy ◽  
Phakic Intraocular Lenses ◽  
Safety And Stability

Abstract Background Myopic anisometropic amblyopia in pediatrics is one of the most challenging clinical situations that can face an ophthalmologist. Conventional correction modalities for myopic anisometropia, using spectacles, contact lenses, and/or occlusion therapy, may not be suitable for some pediatric patients or for some ocular conditions. This may lead to the development of anisometropic amblyopia. The aim of the present study was to evaluate the visual and the refractive efficacy, safety, and stability of Posterior Chamber Phakic Intraocular Lenses (PC-pIOLs) for correcting myopic anisometropic amblyopia in a pediatric cohort. Methods This case series, prospective, interventional study was conducted at Watany Eye Hospital, Cairo, Egypt. It comprised children and teenagers with myopic anisometropic amblyopia and unsuccessful conventional therapy. After implantation of Intraocular Collamer Lenses “ICLs” (Visian ICL, Model V4c, STAAR Surgical, Monrovia, California, USA), postoperative follow-up visits were scheduled, with automated refraction and Pentacam imaging performed. Results The study enrolled 42 eyes of 42 patients. The age range was 3 to 18 years (mean ± SD = 10.74 years ±4.16). The mean preoperative spherical equivalent (SE) was − 12.85 D ± 2.74. The results declared a significant improvement in the postoperative Corrected Distance Visual Acuity “CDVA” (P value < 0.01) and SE (P value < 0.01). The efficacy index had a value of 1.18 ± 0.3 and the safety index was 1.09 ± 0.24. The follow-up visits had a mean ± SD of 14.67 months ±16.56 (range of 1 to 54 months). The results showed a refractive stability, with statistically insignificant improvements in the patients’ visual acuity and refractive status on evaluating the enrolled pediatrics during the follow-up visits compared to the first postoperative visits. No postoperative complications were encountered. Worthy of mention is that there was a significant (80%) non-compliance with the prescribed postoperative occlusion therapy. Conclusions The present study, with the longest reported follow-up range, declared the long-term efficacy, safety, and stability of Visian ICLs for correcting myopic anisometropic amblyopia in pediatrics. The reported non-compliance with occlusion therapy validates the early implantation of Visian ICLs in cases with failed conventional therapy to guard against anisometropic amblyopia.

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