Effects of Tomatine on Aldosterone Release from Zona Glomerulosa Cells in 5/6 Nephrectomized Male Rats

2017 ◽  
Vol 9 (3) ◽  
pp. 130-139 ◽  
Author(s):  
Yi-Ting Hsieh
Keyword(s):  
Zona Glomerulosa ◽  
Male Rats ◽  
Glomerulosa Cells ◽  
Zona Glomerulosa Cells

Effects of acrolein on aldosterone release from zona glomerulosa cells in male rats

Steroids ◽  
2016 ◽  
Vol 111 ◽  
pp. 89-94 ◽  
Author(s):  
Kai-Lee Wang ◽  
Wen-Ching Huang ◽  
Jou-Chun Chou ◽  
Ting-Chun Weng ◽  
Sindy Hu ◽  
...  
Keyword(s):  
Zona Glomerulosa ◽  
Male Rats ◽  
Glomerulosa Cells ◽  
Zona Glomerulosa Cells

The properties of adrenal zona glomerulosa cells after purification by gravitational sedimentation

1974 ◽  
Vol 185 (1081) ◽  
pp. 375-407 ◽  
Keyword(s):  
Angiotensin Ii ◽  
Cyclic Amp ◽  
Microscopic Examination ◽  
Zona Glomerulosa ◽  
Maximal Response ◽  
Zona Fasciculata ◽  
Gravitational Sedimentation ◽  
Rat Adrenals ◽  
Glomerulosa Cells ◽  
Zona Glomerulosa Cells

The densities of latex spheres and biological cells can be reliably determined from their sedimentation rate in an albumin gradient under unit gravitational force. The densities of zona glomerulosa and fasciculata cells of rat adrenals were found to be 1.072 ± 0.004 and 1.040 ± 0.001 respectively. Purified zona glomerulosa cells of rat adrenals can be prepared by gravitational sedimentation of dispersed cells from capsule strippings of the gland, which originally contain 3 to10% zona fasciculata contamination. Electron and phase microscopic examination of the sedimented glomerulosa cells and their steroidogenic response to ACTH and cyclic AMP indicate that they are reasonably free of contamination from zona fasciculata cells. Electron microscopic examination of the purified glomerulosa cells indicates that most of them are reasonably normal in structure. Their basal production of corticosterone is decreased after sedimentation. However, their maximal response of corticosterone output to serotonin and potassium and their response to all potassium concentrations is not significantly altered, indicating normal function for the cells producing steroids. Their maximal responses to ACTH, valine angiotensin II and cyclic AMP are decreased, but, at the doses used, steroidogenesis by the zona fasciculata contamination in the unfractionated preparation would be stimulated by these substances. Purified zona glomerulosa cells have about the same maximal response of corticosterone output (about twofold) to potassium, valine and isoleucine angiotensin II, serotonin and ACTH. The maximal response of the purified zona glomerulosa cells to cyclic AMP is similar to that elicited by valine and isoleucine angiotensin II, potassium, serotonin or ACTH. This indicates that if these stimuli act by increasing cyclic AMP output, then the maximal response of corticosterone output (about twofold) is defined by the limited response of the biosynthetic pathways to cyclic AMP.

Proadrenomedullin N-terminal 20 peptide (PAMP) enhances proliferation of rat zona glomerulosa cells by activating MAPK cascade

Peptides ◽  
2001 ◽  
Vol 22 (11) ◽  
pp. 1909-1912 ◽  
Author(s):  
Piera Rebuffat ◽  
Lucia Gottardo ◽  
Ludwik K Malendowicz ◽  
Giuliano Neri ◽  
Gastone G Nussdorfer
Keyword(s):  
Zona Glomerulosa ◽  
Mapk Cascade ◽  
Glomerulosa Cells ◽  
Zona Glomerulosa Cells

effects of insulin on aldosterone production in rat zona glomerulosa cells

Life Sciences ◽  
1992 ◽  
Vol 50 (23) ◽  
pp. 1781-1787 ◽  
Author(s):  
Dan Petrasek ◽  
Gerard Jensen ◽  
Michael Tuck ◽  
Naftali Stern
Keyword(s):  
Zona Glomerulosa ◽  
Aldosterone Production ◽  
Glomerulosa Cells ◽  
Zona Glomerulosa Cells
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