Chronic kidney disease: role of sympathetic nervous system activation and potential benefits of renal denervation

2013 ◽  
Vol 9 (R) ◽  
pp. R127-R135 ◽  
Author(s):  
Dagmara Hering ◽  
Murray D. Esler ◽  
Markus P. Schlaich
Keyword(s):  
Chronic Kidney Disease ◽  
Nervous System ◽  
Kidney Disease ◽  
Sympathetic Nervous System ◽  
Renal Denervation ◽  
Potential Benefits ◽  
System Activation ◽  
Sympathetic Nervous ◽  
Sympathetic Nervous System Activation

The Role of Sympathetic Nervous System in the Progression of Chronic Kidney Disease in the Era of Catheter Based Sympathetic Renal Denervation

2013 ◽  
Vol 8 (3) ◽  
pp. 197-205 ◽  
Author(s):  
Dimitrios Petras ◽  
Konstantinos Koutroutsos ◽  
Athanasios Kordalis ◽  
Costas Tsioufis ◽  
Christodoulos Stefanadis
Keyword(s):  
Chronic Kidney Disease ◽  
Nervous System ◽  
Kidney Disease ◽  
Sympathetic Nervous System ◽  
Renal Denervation ◽  
Sympathetic Nervous

scholarly journals Recollections of positive early caregiving relate to sympathetic nervous system activation and chronic inflammation in subsequent generations

2018 ◽  
Vol 61 (2) ◽  
pp. 261-274 ◽  
Author(s):  
Emma R. Lyons ◽  
Jessica Norman Wells ◽  
Carolyn M. Scholtes ◽  
Brianna Mintz ◽  
Ryan J. Giuliano ◽  
...  
Keyword(s):  
Nervous System ◽  
Sympathetic Nervous System ◽  
Chronic Inflammation ◽  
System Activation ◽  
Sympathetic Nervous ◽  
Sympathetic Nervous System Activation

scholarly journals Cardiovascular Risk in Chronic Kidney Disease: Role of the Sympathetic Nervous System

2012 ◽  
Vol 2012 ◽  
pp. 1-8 ◽  
Author(s):  
Jeanie Park
Keyword(s):  
Cardiovascular Disease ◽  
Chronic Kidney Disease ◽  
Renal Failure ◽  
Nervous System ◽  
Cardiovascular Risk ◽  
Kidney Disease ◽  
Sympathetic Nervous System ◽  
Renal Disease ◽  
Left Ventricular ◽  
Sympathetic Nervous

Patients with chronic kidney disease are at significantly increased risk for cardiovascular disease and sudden cardiac death. One mechanism underlying increased cardiovascular risk in patients with renal failure includes overactivation of the sympathetic nervous system (SNS). Multiple human and animal studies have shown that central sympathetic outflow is chronically elevated in patients with both end-stage renal disease (ESRD) and chronic kidney disease (CKD). SNS overactivation, in turn, increases the risk of cardiovascular disease and sudden death by increasing arterial blood pressure, arrythmogenicity, left ventricular hypertrophy, and coronary vasoconstriction and contributes to the progression renal disease. This paper will examine the evidence for SNS overactivation in renal failure from both human and experimental studies and discuss mechanisms of SNS overactivity in CKD and therapeutic implications.

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