Usefulness of combined intravascular ultrasound parameters to predict functional significance of coronary artery stenosis and determinants of mismatch

2015 ◽  
Vol 11 (2) ◽  
pp. 163-170 ◽  
Author(s):  
Yun-Kyeong Cho ◽  
Chang-Wook Nam ◽  
Jung-Kyu Han ◽  
Bon-Kwon Koo ◽  
Joon-Hyung Doh ◽  
...  
Keyword(s):  
Coronary Artery ◽  
Intravascular Ultrasound ◽  
Functional Significance ◽  
Coronary Artery Stenosis ◽  
Artery Stenosis ◽  
Ultrasound Parameters

Differential impact of target vessel on the diagnostic performance of resting full-cycle ratio as non-hyperemic physiological assessment

2020 ◽  
Vol 41 (Supplement_2) ◽  
Author(s):  
H Takashima ◽  
H Ohashi ◽  
H Ando ◽  
A Suzuki ◽  
S Sakurai ◽  
...  
Keyword(s):  
Coronary Artery ◽  
Diagnostic Accuracy ◽  
Functional Significance ◽  
Diagnostic Performance ◽  
Coronary Artery Stenosis ◽  
Stable Condition ◽  
Artery Stenosis ◽  
Lesion Length ◽  
Target Vessel ◽  
Roc Curve Analysis

Abstract Background Recently, wire-based resting indices have been recognized as gold standard for evaluating physiological lesion assessment. The resting full-cycle ratio (RFR) is a unique resting index which is calculated as the point of absolutely lowest distal pressure to aortic pressure during entire cardiac cycle. It is unclear whether the diagnostic performance of RFR for detecting functional coronary artery stenosis is similar in each coronary artery. The aim of this study is to compare the diagnostic performance of RFR based on target coronary vessel. Method This study was a prospectively enrolled observational study. A total of 156 consecutive patients with 220 intermediate lesions were enrolled in this study. The RFR was measured after adequately waiting for stable condition, while FFR was measured after intravenous administration of ATP (180mcg/kg/min). Lesions with FFR ≤0.80 were considered functionally significant coronary artery stenosis. Results In all lesions, reference diameter, diameter stenosis, lesion length, RFR, and FFR were 3.0±0.7mm, 45±13%, 13.0±8.8mm, 0.90±0.09, and 0.82±0.10, respectively. Functional significance was observed in 88 lesions (40%) of all lesions. RFR showed a significant correlation with FFR in overall lesions (r=0.774, p<0.001). The ROC curve analysis of RFR showed good accuracy for predicting functional significance (AUC 0.87, diagnostic accuracy 81%) in all subjects. Regarding each target vessel, there were similar and significant positive correlation between RFR and FFR (LAD; r=0.733, p<0.001, LCX; r=0.771, p<0.001, RCA; r=0.769, p<0.001, respectively). The prevalence of discordant between RFR and FFR was significantly different among 3 vessels (LAD 26%, LCX 12%, RCA 13%, respectively, p<0.05 for among 3 groups). Regarding the comparison of ROC curves according to lesion location, AUC was significantly lower in LAD than in LCX and RCA (LAD 0.780, LCX 0.947, RCA 0.926, p<0.01 for LAD compared to LCX, p<0.01 for LAD compared to RCA, respectively). Furthermore, the diagnostic accuracy was significantly different according to target vessel (LAD 74%, LCX 88%, RCA 87%, respectively, p<0.05 for among 3 vessels). Conclusion RFR demonstrated better diagnostic accuracy for evaluating functional lesion severity. The diagnostic performance of RFR was different based on target vessel. RFR is a unique and useful resting index, and it may detect functionally significant coronary stenosis that cannot be detected with other resting indices in daily practice. Funding Acknowledgement Type of funding source: None

PP-007 Diffuse Coronary Spasm Mimicking the Severe Coronary Artery Stenosis to Rule out with Intravascular Ultrasound

2015 ◽  
Vol 115 ◽  
pp. S97
Author(s):  
Cengiz Ozturk ◽  
Mustafa Aparci ◽  
Ali Osman Yıldırım ◽  
Sait Demirkol ◽  
Murat Unlu ◽  
...  
Keyword(s):  
Coronary Artery ◽  
Intravascular Ultrasound ◽  
Coronary Artery Stenosis ◽  
Coronary Spasm ◽  
Artery Stenosis ◽  
Severe Coronary Artery ◽  
Rule Out

Assessment of the Functional Significance of Coronary Artery Stenosis by Dobutamine-Atropine Stress Echocardiography

Cardiology ◽  
1997 ◽  
Vol 88 (4) ◽  
pp. 386-392 ◽  
Author(s):  
Yi-Lwun Ho ◽  
Chau-Chung Wu ◽  
Lung-Chun Lin ◽  
Yen-Bin Liu ◽  
Wen-Jone Chen ◽  
...  
Keyword(s):  
Coronary Artery ◽  
Functional Significance ◽  
Stress Echocardiography ◽  
Coronary Artery Stenosis ◽  
Artery Stenosis
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