scholarly journals Relationship between zinc finger protein 36 (ZFP36) gene polymorphisms and obstructive sleep apnea

2015 ◽  
Vol 14 (2) ◽  
pp. 6733-6743 ◽  
Author(s):  
Y. Zhang ◽  
N.-F. Li ◽  
S. Abulikemu ◽  
D.-L. Zhang ◽  
Y.-C. Wang ◽  
...  
Keyword(s):  
Obstructive Sleep Apnea ◽  
Sleep Apnea ◽  
Zinc Finger ◽  
Gene Polymorphisms ◽  
Zinc Finger Protein ◽  
Finger Protein ◽  
Obstructive Sleep

Leptin and Leptin Receptor Gene Polymorphisms in Obstructive Sleep Apnea Syndrome

CHEST Journal ◽  
2008 ◽  
Vol 133 (1) ◽  
pp. 79-85 ◽  
Author(s):  
Masayuki Hanaoka ◽  
Xiujun Yu ◽  
Kazuhisa Urushihata ◽  
Masao Ota ◽  
Keisaku Fujimoto ◽  
...  
Keyword(s):  
Obstructive Sleep Apnea ◽  
Sleep Apnea ◽  
Obstructive Sleep Apnea Syndrome ◽  
Gene Polymorphisms ◽  
Leptin Receptor ◽  
Receptor Gene ◽  
Sleep Apnea Syndrome ◽  
Obstructive Sleep ◽  
Apnea Syndrome ◽  
Receptor Gene Polymorphisms

scholarly journals Association Study of Serotonin Transporter Gene Polymorphisms with Obstructive Sleep Apnea Syndrome in Chinese Han Population

SLEEP ◽  
2008 ◽  
Vol 31 (11) ◽  
pp. 1535-1541 ◽  
Author(s):  
Weihua Yue ◽  
Huiguo Liu ◽  
Jishui Zhang ◽  
Xianghui Zhang ◽  
Xiaoping Wang ◽  
...  
Keyword(s):  
Obstructive Sleep Apnea ◽  
Sleep Apnea ◽  
Serotonin Transporter ◽  
Gene Polymorphisms ◽  
Sleep Apnea Syndrome ◽  
Transporter Gene ◽  
Chinese Han ◽  
Han Population ◽  
Obstructive Sleep ◽  
Apnea Syndrome

scholarly journals Association of PPARγ2(Pro12Ala) and Neuropeptide Y (Leu7Pro) Gene Polymorphisms with Obstructive Sleep Apnea in Obese Asian Indians

2011 ◽  
Vol 30 (1) ◽  
pp. 31-38 ◽  
Author(s):  
Bharat Bhushan ◽  
Randeep Guleria ◽  
Anoop Misra ◽  
Kalpana Luthra ◽  
Guresh Kumar
Keyword(s):  
Obstructive Sleep Apnea ◽  
Sleep Apnea ◽  
Neuropeptide Y ◽  
Gene Polymorphisms ◽  
Asian Indians ◽  
Fasting Blood Glucose ◽  
Peroxisome Proliferator ◽  
Peroxisome Proliferator Activated Receptor ◽  
Skin Fold ◽  
Obstructive Sleep

Background:Obstructive sleep apnea (OSA) is prevalent in 7.5% in urban Asian Indians.Peroxisome proliferator activated receptor gamma2 (PPARγ2)has been implicated in adipocyte differentiation.Neuropeptide Y (NPY)is also considered as a candidate gene for excess body fat accumulation. The association ofPPARγ2 (Pro12Ala)andNPY (Leu7Pro)gene polymorphisms with OSA has not been studied in Asian Indians.Objective:To study the distribution ofPPARγ2 (Pro12Ala)andNPY (Leu7Pro)polymorphism in Asian Indians with and without OSA.Methods and results:This study was carried out in 252 obese subjects [(body mass index (BMI > 25 kg/m2)]; 142 with OSA and 110 without OSA. Measurements included anthropometric and biochemical parameters (fasting blood glucose, lipid profile, various circumferences and skin-fold thicknesses).PPARγ2 (Pro12Ala) and NPY (Leu7Pro) genepolymorphisms were studied in all subjects. The frequency of the variantallele (Ala12) of PPARγ2 genewas significantly higher in subjects with OSA (14.4%) when compared with subjects without OSA (5.5%; χ2= 9.7;p= 0.001). The distribution of the variantallele (Pro7)ofNPY genewas comparable in subjects with OSA (3.5%) and without OSA (3.6%; χ2= 0.001,p= 0.94).Conclusion:This study reveals a significantly higher frequency ofPPARγ2 (Ala12) allelein obese Asian Indians with OSA when compared to obese Asian Indians without OSA.

scholarly journals Fatty-acid binding protein 4 gene polymorphisms and plasma levels in children with obstructive sleep apnea

2011 ◽  
Vol 12 (7) ◽  
pp. 666-671 ◽  
Author(s):  
Bharat Bhushan ◽  
Abdelnaby Khalyfa ◽  
Karen Spruyt ◽  
Leila Kheirandish-Gozal ◽  
Oscar Sans Capdevila ◽  
...  
Keyword(s):  
Obstructive Sleep Apnea ◽  
Fatty Acid ◽  
Sleep Apnea ◽  
Plasma Levels ◽  
Gene Polymorphisms ◽  
Fatty Acid Binding Protein ◽  
Binding Protein ◽  
Fatty Acid Binding ◽  
Acid Binding Protein ◽  
Obstructive Sleep
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