scholarly journals The Effect of Percutaneous Coronary Intervention on Left Ventricular Diastolic Dysfunction in Patients with Coronary Artery Disease Assessed by Strain Rate Imaging

2014 ◽  
Vol 04 (10) ◽  
pp. 522-529 ◽  
Author(s):  
Fariba Bayat ◽  
Elham Farahani ◽  
Habibollah Saadat
Keyword(s):  
Coronary Artery Disease ◽  
Percutaneous Coronary Intervention ◽  
Coronary Artery ◽  
Coronary Intervention ◽  
Left Ventricular Diastolic Dysfunction ◽  
Left Ventricular ◽  
Strain Rate Imaging ◽  
Percutaneous Coronary ◽  
Ventricular Diastolic Dysfunction ◽  
Artery Disease

scholarly journals Echocardiographic Evaluation of Left Ventricular Diastolic Function after Percutaneous Coronary Intervention in Patients with Coronary Artery Disease

2012 ◽  
Vol 4 (2) ◽  
pp. 127-131
Author(s):  
AK Mandal ◽  
AHK Chowdhury ◽  
AK Choudhury ◽  
AKM Monwarul Islam ◽  
B Guha
Keyword(s):  
Coronary Artery Disease ◽  
Percutaneous Coronary Intervention ◽  
Coronary Artery ◽  
Diastolic Function ◽  
Coronary Intervention ◽  
Left Ventricular Diastolic Dysfunction ◽  
Left Ventricular ◽  
Percutaneous Coronary ◽  
Ventricular Diastolic Dysfunction ◽  
Artery Disease

Background: Although percutaneous coronary intervention (PCI) is an excellent therapy for coronary artery disease, there is a paucity of information on the efficacy of PCI in improving diastolic function, especially in Bangladesh. Because of the high prevalence of left ventricular diastolic dysfunction in coronary artery disease patients and its probable progression to heart failure, an evaluation of the role of PCI in improving diastolic function is required. Objective of the study was to evaluate the impact of percutaneous coronary intervention on left ventricular diastolic dysfunction by Doppler echocardiography in patients with coronary artery disease. Methods: One hundred patients scheduled for elective PCI were enrolled in this study whose left ventricular systolic ejection fraction was normal or only mildly abnormal. Before PCI and 48 hours after PCI, echocardiography was done to evaluate the indices of LV diastolic function in these patients. Results: The mean age of the patients was 52 ± 8.6 years, and 90 patients were male. All had mild to moderate degree of left ventricular diastolic dysfunction. Mitral E wave velocity (58.8 cm/s ± 11.8 before treatment versus 78.1 cm/s ± 13.9, 48 hours after treatment), the peak velocity of late filling due to atrial contraction (mitral A wave velocity) (76.6 cm/s± 13.5 before treatment vs. 67.7cm/s ± 15.2 , 48 hours after treatment) , E/A ratio (0.81± 0.25 before treatment vs. 1.2 ± 0.31 , 48 hours after treatment) showed improvement after PCI. After PCI deceleration time (DT) decreased (245.6msec ±41.6 before treatment versus 175.5msec ± 31.9, 48 hours after treatment), and the difference was statistically significant (p<0.001). It is notable that early diastolic mitral annular velocity (E2 ) improved significantly 48 hours after PCI (5.9cm/s ± 1.7 before treatment vs 7.9 cm/s ±1.6, 48 hours after treatment, p < 0.001). E/ E2 ratio showed significant change 48 hours after PCI; it was statistically significant (10.5±2.8 before treatment vs 9.9 ± 2.4, 48 hours after treatment p<0.001). Conclusion: Improvement in some indices of left ventricular diastolic function after PCI indicates that PCI can be an effective treatment modality for impaired diastolic function in patients with symptomatic coronary artery disease. DOI: http://dx.doi.org/10.3329/cardio.v4i2.10456 Cardiovasc. j. 2012; 4(2): 127-131

scholarly journals Effect of Percutaneous Coronary Intervention on Left Ventricular Diastolic Function in Patients With Coronary Artery Disease

2015 ◽  
Vol 8 (1) ◽  
pp. 270 ◽  
Author(s):  
Nahid Salehi ◽  
Mohammadreza Saidi ◽  
Alireza Rai ◽  
Farid Najafi ◽  
Seedmokhtar Javeedannejad ◽  
...  
Keyword(s):  
Coronary Artery Disease ◽  
Percutaneous Coronary Intervention ◽  
Coronary Artery ◽  
Diastolic Function ◽  
Left Ventricular Diastolic Function ◽  
Coronary Intervention ◽  
Left Ventricular ◽  
Ventricular Diastolic Function ◽  
Percutaneous Coronary ◽  
Artery Disease

<p><strong>BACKGROUND:<em> </em></strong>There is considerable disagreement over the effects of percutaneous coronary intervention (PCI) on left ventricular diastolic function that has necessitated the investigation of diastolic indices. The present study was conducted to evaluate left ventricular diastolic function and its indices, three months after performing the PCI procedure in patients with coronary artery disease (CAD).</p> <p><strong>METHODS:<em> </em></strong>In a quasi-experimental clinical trial study (before and after), 51 patients with CAD scheduled for elective PCI were investigated provided that their Ejection Fraction (EF) was &gt; 30%. Before and three months after PCI, echocardiography was carried out to evaluate left ventricular diastolic indices including the E/Ea as the most important criteria for diagnosis of diastolic heart failure (DHF).<strong></strong></p> <p><strong>RESULTS:<em> </em></strong>Based on the E/Ea indices and after PCI, the number of patients with DHF decreased significantly: 40 patients (78.4%) before PCI versus 28 patients (54.9%) after PCI (p&lt;0.05). The Mean and Standard error of deceleration time (DT), isovolumic relaxation time (IVRT), early diastolic mitral annulus velocity; Ea (E'), E/Ea and left ventricular ejection function (LVEF) indices underwent significant changes. In addition, MVA dur/PVA dur, PVs/PVd, and E/Ea indices had changed significantly after PCI in both genders. However, no significant difference was reported for the other indices.</p> <p><strong>CONCLUSION:<em> </em></strong>The E/Ea ratio as an important criterion for diagnosis of DHF was improved after PCI. Improvement of several other diastolic indices was observed after the PCI procedure. It can be concluded that PCI can be an effective treatment modality in patients with left ventricular diastolic indices.</p>

Sign in / Sign up

Export Citation Format

Share Document