scholarly journals Spindle Cell Lipoma of the Oral Cavity: A Clinico-Pathologic Analysis of 35 Reported Cases

2013 ◽  
Vol 04 (03) ◽  
pp. 196-201 ◽  
Author(s):  
Esther Manor ◽  
Netta Sion-Vardy ◽  
Peter A. Brennan ◽  
Lipa Bodner
Keyword(s):  
Oral Cavity ◽  
Spindle Cell ◽  
Spindle Cell Lipoma ◽  
Pathologic Analysis

Atypical Spindle Cell Lipomatous Lesion Resected From Patient With History of CLL

2020 ◽  
Vol 86 (9) ◽  
pp. 1208-1211
Author(s):  
Chase J. Wehrle ◽  
J. Will Daigle ◽  
Asad Ullah ◽  
Suash Sharma ◽  
Edmond F. Ritter ◽  
...  
Keyword(s):  
Spindle Cell ◽  
Lymphocytic Leukemia ◽  
Left Shoulder ◽  
Spindle Cell Lipoma ◽  
Atypical Lipomatous Tumor ◽  
Lipomatous Tumor ◽  
Adipocytic Tumors ◽  
History Of ◽  
Pathologic Analysis ◽  
Mdm2 Amplification

Atypical spindle cell lipomatous neoplasm, also known as well-differentiated spindle cell liposarcoma, represents a newly discovered entity of adipocytic tumors. Recent research has shown this tumor variant to be more related to spindle cell lipoma, rather than the originally hypothesized atypical lipomatous tumor spectrum. Here we present a case of a 58-year-old man with a history of chronic lymphocytic leukemia with an enlarging mass on the posterior left shoulder, initially hypothesized to be a benign lipoma. However, magnetic resonance imaging showed a large, multiseptated, heterogeneous mass concerning for soft tissue sarcoma. After resection, pathologic analysis showed cells closely resembling spindle cell lipoma, with additional cellular and fascicular zones containing lipoblasts and mitotic figures. Molecular analysis showed no MDM2 amplification. This lack of amplification indicates this tumor is distinctly different from an atypical lipomatous tumor, which characteristically displays MDM2 amplification. However, tumor expression of RB1 was normal. The majority of atypical spindle cell lipomatous neoplasms are associated with RB1 deletions. We conclude that we have a unique example of an atypical spindle cell lipomatous tumor.

scholarly journals A 37 mm Spindle Cell Lipoma on the Floor of the Mouth

2019 ◽  
Vol 2019 ◽  
pp. 1-4 ◽  
Author(s):  
Eve Malthiery ◽  
Valérie Costes-Martineau ◽  
Marie-Alix Fauroux ◽  
Jacques-Henri Torres
Keyword(s):  
Oral Cavity ◽  
Local Anesthesia ◽  
High Frequency ◽  
Spindle Cell ◽  
Spindle Cell Lipoma ◽  
Functional Consequence ◽  
Histological Features ◽  
Floor Of The Mouth ◽  
Spindle Cells ◽  
Male Patients

Spindle cell lipoma (SCL) is a rare variety of lipoma that mostly arises in male patients and rarely affects the oral cavity. The floor of the mouth is an uncommon site for SCL, and very few cases have been reported in this location. A case of SCL is reported in a 70-year-old woman who had noticed a swelling of the floor of the mouth without any functional consequence. Both ultrasonography and RMI suggested a diagnosis of ranula, whereas clinical palpation showed a nonfluctuant mass. The lesion was excised under local anesthesia. A 37×32 mm encapsulated yellow mass was removed. Histological features (mature adipocytes and CD34+ spindle cells) led to a diagnosis of SCL. Medical imaging assessment of this lesion could have been influenced by the high frequency of the ranulas in the floor of the mouth. This case appears to be quite infrequent because of its location (floor of the mouth), its size (over 3.5 cm), and the patient’s gender (female).

Spindle Cell Lipoma of the Oral Cavity

2001 ◽  
Vol 45 (1) ◽  
pp. 93-98 ◽  
Author(s):  
Nicholas Agoff ◽  
Andrew L. Folpe ◽  
Verena S. Grieco ◽  
Rochelle L. Garcia
Keyword(s):  
Oral Cavity ◽  
Spindle Cell ◽  
Spindle Cell Lipoma

Spindle cell lipoma of the oral cavity

1995 ◽  
Vol 24 (5) ◽  
pp. 363-364 ◽  
Author(s):  
Konstantinos Tosios ◽  
Stavros I. Papanicolaou ◽  
Nikiforos Kapranos ◽  
Nick Papadogeorgakis
Keyword(s):  
Oral Cavity ◽  
Spindle Cell ◽  
Spindle Cell Lipoma

Spindle Cell Lipoma of the Oral Cavity

2006 ◽  
Vol 28 (1) ◽  
pp. 28-31 ◽  
Author(s):  
Steven D Billings ◽  
John D Henley ◽  
Don-John Summerlin ◽  
Saeed Vakili ◽  
Charles E Tomich
Keyword(s):  
Oral Cavity ◽  
Spindle Cell ◽  
Spindle Cell Lipoma

Spindle-cell variant of intralingual lipoma – report of a case with literature review

1999 ◽  
Vol 113 (6) ◽  
pp. 587-589 ◽  
Author(s):  
Sunil N. Dutt ◽  
David M. East ◽  
Yousuf Saleem ◽  
E. L. Jones
Keyword(s):  
Literature Review ◽  
Oral Cavity ◽  
Spindle Cell ◽  
Myxoid Liposarcoma ◽  
Spindle Cell Lipoma ◽  
Rare Lesion ◽  
Benign Nature ◽  
Cell Variant

AbstractA true lipoma is a rare lesion in the oral cavity. A histologically distinct variant is the spindle-cell variety, which is an innocuous lesion that can simulate a myxoid liposarcoma.We report a case of intra-oral spindle-cell lipoma in a 42-year-old female and have reviewed the literature pertaining to this unusual histopathological entity. A wareness of the condition is essential for both clinicians and pathologists to avoid any misinterpretation of the benign nature of this condition.

SPINDLE CELL LIPOMA OF THE ORAL CAVITY: CASE REPORT OF AN UNCOMMON AND DISTINCT VARIANT OF LIPOMA

2020 ◽  
Vol 129 (1) ◽  
pp. e67
Author(s):  
BRUNA FERNANDES DO CARMO CARVALHO ◽  
NAYARA DE SÁ RODRIGUES ◽  
JANETE DIAS ALMEIDA ◽  
PASQUAL BONZANINI NETO ◽  
ANA LIA ANBINDER ◽  
...  
Keyword(s):  
Case Report ◽  
Oral Cavity ◽  
Spindle Cell ◽  
Spindle Cell Lipoma

scholarly journals Lipoma intraoral atípico: relato de caso

2020 ◽  
Vol 9 (3) ◽  
Author(s):  
Naíza Menezes Medeiros Abrahim ◽  
Gesom Avohai Dias Sombra ◽  
Jardel dos Santos Silva ◽  
André Luiz Carvalho Barreiros ◽  
Jeconias Câmara ◽  
...  
Keyword(s):  
Case Report ◽  
Oral Cavity ◽  
Spindle Cell ◽  
Immunohistochemical Study ◽  
Review Of Literature ◽  
Review Of The Literature ◽  
Spindle Cell Lipoma ◽  
Maxillofacial Region ◽  
Rare Case Report ◽  
Head Neck

Os lipomas são tumores de tecido mole que raramente acometem a cavidade oral. A lesão apresenta variáveis clínicas e histopatológicas que não alteram seu prognóstico. Apesar de suas características comuns, a lesão pode estabelecer diagnóstico diferencial com outras lesões de tecido mole. O objetivo desse artigo é relatar a apresentação clínica não usual de um lipoma localizado em mucosa jugal com 3cm em sua maior extensão, em paciente do sexo masculino com 56 anos de idade. O plano de tratamento foi a biópsia excisional com excelente prognóstico.Descritores: Boca; Lipoma; Neoplasia Bucais.ReferênciasJuliasse LE, Nonaka CF, Pinto LP, Freitas Rde A, Miguel MC. Lipomas of the oral cavity: clinical and histopathologic study of 41 cases in a Brazilian population. Eur Arch Otorhinolaryngol. 2010;267(3):459-65.Naruse T, Yanamoto S, Yamada S, Rokutanda S, Kawakita A, Takahashi H et al. Lipomas of the oral cavity: clinicopathological and immunohistochemical study of 24 cases and review of the literature. Indian J Otolaryngol Head Neck Surg. 2015;67(Suppl 1):67-73.Manor E, Sion-Vardy N, Joshua BZ, Bodner L. Oral lipoma: analysis of 58 new cases and review of the literature. Ann Diagn Pathol. 2011;15(4):257-61.Avelar LR, Carvalho RWF, Falcão PGCB, Antunes AA, Andrade ESS et al. Lipomas da Região Oral e Maxilofacial: Estudo Retrospectivo de 16 Anos no Brasil. Rev Port Estomatol Cir Maxilofac 2008;49(4):207-11.Said-Al-Naief N, Zahurullah FR, Sciubba JJ. Oral spindle cell lipoma. Ann Diagn Pathol. 2001;5(4):207-15.Egido-Moreno S, Lozano-Porras AB, Mishra S, Allegue-Allegue M, Marí-Roig A, López-López J. Intraoral lipomas: Review of literature and report of two clinical cases. J Clin Exp Dent. 2016;8(5):e597-603. A RK, N PN, Y S, A VK, D KK. Intraoral lipoma: a rare case report and review of literature. J Clin Diagn Res. 2013;7(12):3090-91.Raj M, Ramadoss T, Anuradha G, Devi S. Intraoral lipoma: review of literature and case report. J Indian Acad Oral Med Radiol. 2012; 24(1):36-38Carvalho MF, Junqueira TP, Souza RR, Capistrano HM, Chaves MGAM.The importance of early diagnosis of large lipomas in the maxillofacial region. Rev Cubana Estomatol. 2011;48(1):77-83Noro Filho GA, Caputo BV, Santos CC, Souza RS, Giovani EM, Scabar LF et al. Diagnosis and treatment of intraoral lipoma: a case report. J Health Sci Inst. 2010;28(2):129-31.

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