scholarly journals Natural Products for the Treatment of Type 2 Diabetes Mellitus

2014 ◽  
Vol 05 (05) ◽  
pp. 487-503 ◽  
Author(s):  
Rupal Patel Mansukhani ◽  
Lucio R. Volino ◽  
Rozena Varghese
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Natural Products

scholarly journals Natural Products for the Treatment of Type 2 Diabetes Mellitus

Planta Medica ◽  
2015 ◽  
Vol 81 (12/13) ◽  
pp. 975-994 ◽  
Author(s):  
José Ríos ◽  
Flavio Francini ◽  
Guillermo Schinella
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Natural Products

scholarly journals Lipophagy: A New Perspective of Natural Products in Type 2 Diabetes Mellitus Treatment

2021 ◽  
Vol Volume 14 ◽  
pp. 2985-2999
Author(s):  
Mingyue Huang ◽  
Xinyu Yang ◽  
Zhenzhen Wang ◽  
Jianglan Long ◽  
Aiting Wang ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Natural Products ◽  
New Perspective ◽  
Diabetes Mellitus Treatment

scholarly journals Docking Studies on Potential Mechanisms for Decreasing Insulin Resistance by the Tangzhiqing Herbal Formula

2020 ◽  
Vol 2020 ◽  
pp. 1-11
Author(s):  
Jia Hao ◽  
Lifeng Han ◽  
Yi Zhang ◽  
Tao Wang
Keyword(s):  
Diabetes Mellitus ◽  
Insulin Resistance ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Natural Products ◽  
Salvia Miltiorrhiza ◽  
Regulation Mechanism ◽  
Herbal Formula ◽  
Active Components

Insulin resistance (IR) is considered as one of the principal pathways of type 2 diabetes mellitus pathogenesis and is associated with a series of abnormal signaling pathways. Tangzhiqing (TZQ) herbal formula is a well-known antidiabetic traditional Chinese medicine and has been used to treat type 2 diabetes mellitus and prediabetes for many years in China. We selected 13 natural products as representative compounds of the main active components in TZQ to investigate the interaction of these natural products with key signal proteins associated with IR using two different docking calculations. Salvianolic acids A and C (phenolic acids from Salvia miltiorrhiza), rutin (a flavonoid from Morus alba), paeoniflorin (a saponin from Paeonia lactiflora), and quercitrin (a flavonoid from Crataegus pinnatifida) showed great docking abilities towards multiple target proteins. These results have contributed to a clearer understanding regarding the regulation mechanism of TZQ on IR and have provided direction for further pharmacological studies.

Sign in / Sign up

Export Citation Format

Share Document