scholarly journals Testing Low Doses of Caffeine on Respiratory Resistance Using the Airflow Perturbation Device

2017 ◽  
Vol 07 (02) ◽  
pp. 53-61
Author(s):  
Mary Kate Montgomery ◽  
Allen Luk ◽  
Arthur T. Johnson ◽  
Jafar Vossoughi
Keyword(s):  
Low Doses ◽  
Respiratory Resistance ◽  
Airflow Perturbation Device

scholarly journals The Effect of Exercise on Respiratory Resistance in Athletes With and Without Paradoxical Vocal Fold Motion Disorder

2015 ◽  
Vol 24 (3) ◽  
pp. 470-479 ◽  
Author(s):  
Sally J. K. Gallena ◽  
Nancy Pearl Solomon ◽  
Arthur T. Johnson ◽  
Jafar Vossoughi ◽  
Wei Tian
Keyword(s):  
Repeated Measures ◽  
Vocal Fold ◽  
Female Athletes ◽  
Exercise Duration ◽  
Treadmill Running ◽  
Respiratory Resistance ◽  
The Difference ◽  
Airflow Perturbation Device ◽  
Vocal Fold Motion ◽  
Paradoxical Vocal Fold Motion

Purpose An investigational, portable instrument was used to assess inspiratory (R i ) and expiratory (R e ) resistances during resting tidal breathing (RTB), postexercise breathing (PEB), and recovery breathing (RB) in athletes with and without paradoxical vocal fold motion disorder (PVFMD). Method Prospective, controlled, repeated measures within-subject and between-groups design. Twenty-four teenage female athletes, 12 with and 12 without PVFMD, breathed into the Airflow Perturbation Device for baseline measures of respiratory resistance and for two successive 1-min trials after treadmill running for up to 12 min. Exercise duration and dyspnea ratings were collected and compared across groups. Results Athletes with PVFMD had lower than control R i and R e values during RTB that significantly increased at PEB and decreased during RB. Control athletes' R e decreased significantly from RTB to PEB but not from PEB to RB, whereas R i did not change from RTB to PEB but decreased from PEB to RB. Athletes without PVFMD ran longer, providing lower dyspnea ratings. Conclusion Immediately following exercise, athletes with PVFMD experienced increased respiratory resistance that affected their exercise performance. The difference in resting respiratory resistances between groups is intriguing and could point to anatomical differences or neural adaptation in teenagers with PVFMD. The Airflow Perturbation Device appears to be a clinically feasible tool that can provide insight into PVFMD and objective data for tracking treatment progress.

scholarly journals Comparison of Respiratory Resistance Measurements Made with an Airflow Perturbation Device with Those from Impulse Oscillometry

2013 ◽  
Vol 2013 ◽  
pp. 1-11 ◽  
Author(s):  
J. Pan ◽  
A. Saltos ◽  
D. Smith ◽  
A. Johnson ◽  
J. Vossoughi
Keyword(s):  
Mechanical System ◽  
Impulse Oscillometry ◽  
Respiratory Resistance ◽  
Limited Data ◽  
Flow Paths ◽  
Human Volunteers ◽  
Flow Generator ◽  
Sinusoidal Flow ◽  
Airflow Perturbation Device ◽  
Strong Linear Relationship

The airflow perturbation device (APD) has been developed as a portable, easy to use, and a rapid response instrument for measuring respiratory resistance in humans. However, the APD has limited data validating it against the established techniques. This study used a mechanical system to simulate the normal range of human breathing to validate the APD with the clinically accepted impulse oscillometry (IOS) technique. The validation system consisted of a sinusoidal flow generator with ten standardized resistance configurations that were shown to represent a total range of resistances from 0.12 to 0.95 kPa·L−1·s (1.2–9.7 cm H2O·L−1·s). Impulse oscillometry measurements and APD measurements of the mechanical system were recorded and compared at a constant airflow of 0.15 L·s−1. Both the IOS and APD measurments were accurate in assessing nominal resistance. In addition, a strong linear relationship was observed between APD measurements and IOS measurements (R2 = 0.999). A second series of measurements was made on ten human volunteers with external resistors added in their respiratory flow paths. Once calibrated with the mechanical system, the APD gave respiratory resistance measurements within 5% of IOS measurements. Because of their comparability to IOS measurements, APD measurements are shown to be valid representations of respiratory resistance.

Exercise-induced respiratory resistance changes as measured with the airflow perturbation device

2004 ◽  
Vol 26 (1) ◽  
pp. 29-38 ◽  
Author(s):  
Nischom K Silverman ◽  
Arthur T Johnson ◽  
William H Scott ◽  
Frank C Koh
Keyword(s):  
Respiratory Resistance ◽  
Exercise Induced ◽  
Airflow Perturbation Device

Validation of Respiratory Resistance Measurements

2011 ◽  
Author(s):  
James Pan ◽  
Andrew Saltos ◽  
Dan Smith ◽  
Arthur Johnson ◽  
Jafar Vossoughi
Keyword(s):  
Flow Rate ◽  
Volumetric Flow Rate ◽  
Impulse Oscillometry ◽  
Respiratory Resistance ◽  
Calibration System ◽  
Limited Data ◽  
Normal Range ◽  
Flow Generator ◽  
Sinusoidal Flow ◽  
Airflow Perturbation Device

The airflow perturbation device (APD) has been developed as a portable, easy to use, and rapid-response instrument for noninvasively measuring respiratory resistance in humans. However, the APD has limited data validating it against established techniques; moreover, a method does not exist to standardize resistance measurement outputs between APD units. This study proposes a system that simulates the normal range of human breathing to validate the APD with the clinically accepted impulse oscillometry technique. Two respiratory resistance ranges were tested. The validation system consisted of a sinusoidal flow generator with ten standardized resistance configurations that were shown to represent a total range of resistances from 0.7000–9.4475 cmH2O·L−1·s−1. Impulse oscillometry (IOS) measurements and APD measurements of the calibration system were recorded and compared at a constant volumetric flow rate of 0.150 L·s−1. Both IOS and the APD consistently failed to estimate nominal resistance accurately. However, a strong second-order relationship was observed between APD measurements and IOS measurements (R2 = 0.997). Because of their comparability to IOS measurements, APD measurements are shown to be valid representations of respiratory resistance in a standard pneumatic model.

scholarly journals Respiratory resistance measured by an airflow perturbation device

1999 ◽  
Vol 20 (1) ◽  
pp. 21-35 ◽  
Author(s):  
Christopher G Lausted ◽  
Arthur T Johnson
Keyword(s):  
Respiratory Resistance ◽  
Airflow Perturbation Device
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