scholarly journals A Retrospective Review: Vaginal versus Abdominal Hysterectomy for Benign Gynecological Diseases in a Tertiary Canter

2016 ◽  
Vol 06 (12) ◽  
pp. 761-768
Author(s):  
Lujain Bukhari ◽  
Ayman A. Bukhari ◽  
Omar F. Albakri ◽  
Arwa F. Alshamrani ◽  
Walaa E. Alahmadi ◽  
...  
Keyword(s):  
Retrospective Review ◽  
Abdominal Hysterectomy ◽  
Gynecological Diseases ◽  
Benign Gynecological Diseases

scholarly journals Analytical and clinical evaluation of an electrochemiluminescence immunoassay for the determination of CA 125

1998 ◽  
Vol 44 (12) ◽  
pp. 2530-2536 ◽  
Author(s):  
Huub E van Ingen ◽  
Daniel W Chan ◽  
Walter Hubl ◽  
Hayato Miyachi ◽  
Rafael Molina ◽  
...  
Keyword(s):  
Multicenter Trial ◽  
Ca 125 ◽  
Newly Diagnosed ◽  
Cutoff Value ◽  
Gynecological Diseases ◽  
Electrochemiluminescence Immunoassay ◽  
Benign Gynecological Diseases ◽  
International Multicenter ◽  
Apparently Healthy

Abstract The CA 125 II assay on the Elecsys® 2010 analyzer was evaluated in an international multicenter trial. Imprecision studies yielded within-run CVs of 0.8–3.3% and between-day CVs of 2.4–10.9%; CVs for total imprecision in the manufacturer’s laboratory were 2.4–7.8%. The linear range of the assay extended to at least 4500 kilounits/L (three decades). Interference from triglycerides (10.3 mmol/L), bilirubin (850 μmol/L), hemoglobin (1.1 mmol/L), anticoagulants (plasma), and several widely used drugs was undetectable. Method comparisons with five other CA 125 II assays showed good correlation but differences in standardization. A 95th percentile cutoff value of 35 kilounits/L was calculated from values measured in 593 apparently healthy (pre- and postmenopausal) women. In 95% of patients with benign gynecological diseases CA 125 was ≤190 kilounits/L; 63% of patients with newly diagnosed ovarian carcinoma had values >190 kilounits/L. A comparison of CA 125 values obtained with the Elecsys test and with other common CA 125 tests in monitored patients being treated for ovarian cancer showed identical patterns. In conclusion, the Elecsys CA 125 II assay is linear over a broad range, yields precise and accurate results, is free from interferences, and compares well with other assays.

scholarly journals Abdominal hysterectomy: analysis of clinico-histopathological correlation in Western Rajasthan, India

2017 ◽  
Vol 6 (3) ◽  
pp. 1012
Author(s):  
Dinesh Pal Yadav ◽  
Ramgopal Yadav ◽  
Indra Bhati
Keyword(s):  
Clinical Diagnosis ◽  
Histopathological Examination ◽  
Abdominal Hysterectomy ◽  
Major Surgery ◽  
Clinical Impression ◽  
Histopathological Analysis ◽  
Age Group ◽  
Histopathological Correlation ◽  
Wide Range ◽  
Gynecological Diseases

Background: Hysterectomy is the most common gynecological surgery done in the females worldwide as it provides definitive cure to a wide range of gynecological diseases, both benign and malignant. The indications to perform this major surgery should always be justified and the pathology should be proved histopathologically. Histopathological analysis and review is mandatory to evaluate the appropriateness of the hysterectomy.Methods: A retrospective, longitudinal study was conducted in the Department of Obstetrics and Gynecology, UMAID Hospital, Dr. S.N. M.C. Jodhpur (Raj.) during October 2014 to March 2015.Total 105 cases were studied during this period. The study included all women undergoing planned abdominal hysterectomy. Data was recorded on proformas, including demographic characteristics and clinical features. Hysterectomy specimens were saved in 10% formalin and sent to the Department of Pathology. Histopathology reports were analyzed and compared with the indications of surgery to draw various informative conclusions.Results: Of 105 cases, 55(52.38%) were in the age group of 41 – 50, which comprised the commonest age group undergoing the surgery. Maximum women (95%) those underwent hysterectomy were multiparous. Most common preoperatively clinical diagnosis was leiomyoma uterus which was diagnosed clinically and sonographically in 51(48.57%) cases. On Histopathological examination, the commonest pathology, similar to clinical impression, was found to be Leiomyoma at 50.48% (n = 53). Adenomyosis (21.90%) was detected as Second most common pathology. Histopathological confirmation of pre-operative diagnosis was 89% for malignancy, 96% for fibroids, 100% for adenomyosis, 100% for pelvic inflammatory disease.Conclusions: There was a high correlation when the clinical diagnosis was a fibroid, adenomyosis and ovarian mass. Every hysterectomy specimen should be subjected to histopathological examination because it is mandatory for conforming diagnosis and ensuring optimal management, in particular of malignant disease.

scholarly journals A RETROSPECTIVE REVIEW OF ABDOMINAL HYSTERECTOMY IN A TEACHING HOSPITAL

2016 ◽  
Vol 3 (2) ◽  
pp. 16-19
Author(s):  
Sarita Acharya ◽  
Sweety Shrestha ◽  
M. N. Pal
Keyword(s):  
Postoperative Complications ◽  
Clinical Diagnosis ◽  
Teaching Hospital ◽  
Retrospective Review ◽  
Abdominal Hysterectomy ◽  
Clinical Indication ◽  
Histopathological Diagnosis ◽  
Medical Sciences ◽  
Duration Of Symptoms ◽  
Indications And Complications

INTRODUCTION: Hysterectomy is the most commonly performed gynaecological surgery throughout the world. It may be life saving procedure in acute uterine hemorrhage; whereas improves the quality of life in a patient with certain uterine pathology such as fibroids, endometriosis and uterine prolapse. The objective of this study is to review the indications and complications of abdominal hysterectomy as well as to assess the correlation of preoperative clinical and ultrasonographic diagnosis with histopathology of hysterectomy specimens. MATERIAL AND METHODS: A retrospective review of medical records of patients who underwent abdominal hysterectomy between January 2010 and July 2012 in the College of Medical Sciences Teaching Hospital, Nepal was done. Various demographic and pertinent clinical informations were retrieved. Clinical presentations, indications and complications of the hysterectomy as well as the correlation between the clinical diagnosis, ultrasound findings and histopathological diagnosis of the hysterectomy specimen was studied. RESULTS: Between January 2010 and July 2012 a total of 139 patients had undergone abdominal hysterectomy for various indications. The mean age at the time of hysterectomy was 45.5 years. Abnormal vaginal bleeding and lower abdominal pain were the main presenting complaints. The median duration of symptoms was 12 months. Fourty three (40%) had hysterectomy alone and 96 (60%) had hysterectomy with salpingo oophorectomy. The most common clinical indication for hysterectomy was fibroid uterus (40.3%) followed by benign ovarian tumor (18.7%) and dysfunctional uterine bleeding (17.3%). There were no major postoperative complications. The correlation between clinical diagnosis and histopathology was significant at 0.01 level using Pearson correlations. CONCLUSION: Uterine fibroids and benign ovarian tumors are the common indications for abdominal hysterectomy. Postoperative complications are minimal and most of the time the clinical diagnosis correlates with the postoperative histopathological diagnosis.Journal of Universal College of Medical Sciences (2015) Vol.03 No.02 Issue 10Pages 16-19

Sign in / Sign up

Export Citation Format

Share Document