scholarly journals Cognitive Deficits in Primary Brain Tumours: A Framework for Management and Rehabilitation

2014 ◽  
Vol 05 (01) ◽  
pp. 74-81 ◽  
Author(s):  
Michael Back ◽  
Elizabeth Back ◽  
Marina Kastelan ◽  
Helen Wheeler
Keyword(s):  
Cognitive Deficits ◽  
Brain Tumours ◽  
Primary Brain Tumours

scholarly journals Assessment of Structural Disconnections In Gliomas: Comparison of Indirect And Direct Approaches

2021 ◽  
Author(s):  
Erica Silvestri ◽  
Umberto Villani ◽  
Manuela Moretto ◽  
Maria Colpo ◽  
Alessandro Salvalaggio ◽  
...  
Keyword(s):  
Cognitive Deficits ◽  
Brain Tumours ◽  
Low Grade ◽  
Clinical Progression ◽  
Primary Brain Tumours ◽  
Tumoral Lesion ◽  
Definition Of ◽  
Brain Gliomas ◽  
First Time ◽  
The Brain

Abstract Gliomas are amongst the most common primary brain tumours in adults and are often associated with poor prognosis. Understanding the extent of white matter (WM) which is affected outside the tumoral lesion may be of paramount importance to explain cognitive deficits and the clinical progression of the disease. To this end, we explored both direct (i.e., tractography based) and indirect (i.e., atlas based) approaches to quantifying WM structural disconnections in a cohort of 50 high- and low-grade glioma patients. While these methodologies have recently gained popularity in the context of stroke, to our knowledge this is the first time they are applied in patients with brain tumours. More specifically, in this work we present a quantitative comparison of the disconnection maps provided by the two methodologies by applying well known metrics of spatial similarity, extension and correlation. Given the important role the oedematous tissue plays in the physiopathology of tumours, we performed these analyses both by including and excluding it in the definition of the tumoral lesion. This was done to investigate possible differences determined by this choice.We found that direct and indirect approaches offer two distinct pictures of structural disconnections in patients affected by brain gliomas, presenting key differences in several regions of the brain. Following the outcomes of our analysis, we eventually discuss the strengths and pitfalls of these two approaches when applied in this critical field.

Over-All Accuracy of 99mTc-Pertechnetate Brain Scanning for Brain Tumours – Study of 471 Patients

1978 ◽  
Vol 17 (06) ◽  
pp. 249-253
Author(s):  
E. Pétursson ◽  
B. Sigurbjörnsson ◽  
D. Davidsson ◽  
O.G. Björnsson
Keyword(s):  
Brain Metastases ◽  
Brain Tumours ◽  
True Negative ◽  
Diagnostic Reliability ◽  
Radioisotope Scanning ◽  
Primary Brain Tumours ◽  
99Mtc Pertechnetate

A 3-year follow-up and re-evaluation of all scans on all patients referred for brain scanning in Iceland during 1 year was performed in order to assess the diagnostic reliability of radioisotope scanning for brain tumours. The study included 471 patients. Of these 25 had primary brain tumours and 7 brain metastases. Scans were positive and correctly interpreted in68 % of the patients with primary brain tumours and in 3 of the 7 patients with metastases. The over-all accuracy of brain scanning for brain tumours defined as the total number of correct positive scans and correct negative scans versus total number of scans examined was 96%, this figure being mainly influenced by the high number of true negative scans.

scholarly journals Mortality due to primary brain tumours in China and detection rate in people with suspected symptoms: a nationally representative cross-sectional survey

2021 ◽  
Vol 19 (1) ◽  
Author(s):  
Bin Jiang ◽  
Hongmei Liu ◽  
Dongling Sun ◽  
Haixin Sun ◽  
Xiaojuan Ru ◽  
...  
Keyword(s):  
Brain Tumour ◽  
Brain Tumours ◽  
Detection Rate ◽  
Epidemiological Data ◽  
Cross Sectional Survey ◽  
Cross Sectional ◽  
Detection Rates ◽  
Primary Brain Tumours ◽  
Symptom Screening ◽  
Nationally Representative

Abstract Background and purpose Epidemiological data on primary brain tumours (PBTs) are lacking due to the difficulty in case ascertainment among the population. Thus, we aimed to estimate mortality due to PBTs in China nationwide and the detection rate in people with suspected symptoms. Methods A multistage, complex sampling survey regarding mortality due to PBTs in Chinese individuals was carried out by reviewing all causes of death within a year. The detection rates in people with suspected symptoms were estimated based on PBT symptom screening and neurologist reviews and compared between groups by logistic regression analysis. Results Weighted mortality due to PBT was 1.6 (0.8–3.3) per 100,000 population in Chinese individuals, 1.8 (0.7–4.6) per 100,000 population in men, and 1.5 (0.5–4.5) per 100,000 population in women. Among 14,990 people with suspected symptoms, the PBT detection rate was 306.9 (95% CI 224.7–409.3) per 100,000 population in the total population, 233.0 (95% CI 135.7–373.1) per 100,000 population in men, and 376.9 (95% CI 252.4–546.3) per 100,000 population in women. People with an unsteady gait (OR 2.46; 95% CI 1.09–5.51; P=0.029), visual anomalies (3.84; 1.88–7.85; P<0.001), and headache (2.06; 1.10–3.86; P=0.023) were more likely to have a brain tumour than those without corresponding symptoms, while people with dizziness/vertigo were less likely to have a brain tumour than those without corresponding symptoms (0.45; 0.23–0.87; P=0.017). Conclusions Mortality due to PBT in China was low, with a nationwide estimate of 21,215 (10,427–43,165) deaths attributable to PBTs annually. However, the detection rate of PBTs can be greatly improved based on symptom screening in the population.

Patients with Primary Brain Tumours Have Elevated Serum Titres of Antibodies to the Myelin Glycolipid Sulphatide

2001 ◽  
Vol 45 (1) ◽  
pp. 38-42 ◽  
Author(s):  
C. Nygren ◽  
H. v. Holst ◽  
K. Ericson ◽  
P. Fredman
Keyword(s):  
Brain Tumours ◽  
Elevated Serum ◽  
Primary Brain Tumours

3524 POSTER Epidemiology of Primary Brain Tumours in Georgia – First-year Results of a Prospective Population-based Study

2011 ◽  
Vol 47 ◽  
pp. S253 ◽  
Author(s):  
T. Gigineishvili ◽  
N. Shengelia ◽  
S. Kartsivadze ◽  
G. Shalashvili ◽  
S. Tsiskaridze ◽  
...  
Keyword(s):  
Brain Tumours ◽  
Population Based ◽  
First Year ◽  
Population Based Study ◽  
Primary Brain Tumours

Pituitary and Neuroendocrine Surgery

2019 ◽  
pp. 213-224
Author(s):  
Douglas A. Colquhoun ◽  
Edward C. Nemergut
Keyword(s):  
Brain Tumours ◽  
Disease Process ◽  
Operative Management ◽  
Neuroendocrine System ◽  
Pituitary Tumours ◽  
Anatomy And Physiology ◽  
The Third ◽  
Primary Brain Tumours ◽  
Operative Evaluation ◽  
Multi Disciplinary Team

Surgeries on the pituitary and neuroendocrine system are commonly encountered in neuroanaesthesia practice. Pituitary tumours are the third most common brain tumour, comprising about 10–15% of all primary brain tumours. Patients with pituitary tumours pose unique challenges to the anaesthestist caring for them in the peri-operative period, and they require the care of a multi-disciplinary team to accurately diagnose and manage their disease process as they undergo surgical resection. This chapter on pituitary and neuroendocrine surgery includes sections on anatomy and physiology, systemic changes associated with pituitary tumours, pre-operative evaluation (including intra-operative management), and common complications (for example, diabetes insipidus).

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