scholarly journals Circulating Tumor Cell Cultures as a Predictive Marker during Salvage Therapy of Refractory Merkel Cell Carcinoma with Chemotherapy and Electron Beam Radiation

2013 ◽  
Vol 04 (07) ◽  
pp. 1162-1166 ◽  
Author(s):  
Sreekanth Donepudi ◽  
Susan A. Reisinger ◽  
John R. McGregor ◽  
Shweta Tharkar ◽  
Suzanne Samlowski ◽  
...  
Keyword(s):  
Electron Beam ◽  
Tumor Cell ◽  
Cell Carcinoma ◽  
Cell Cultures ◽  
Salvage Therapy ◽  
Predictive Marker ◽  
Circulating Tumor Cell ◽  
Merkel Cell ◽  
Beam Radiation ◽  
Electron Beam Radiation

scholarly journals Circulating Tumor Cell Detection and Polyomavirus Status in Merkel Cell Carcinoma

2020 ◽  
Vol 10 (1) ◽  
Author(s):  
Magali Boyer ◽  
Laure Cayrefourcq ◽  
Françoise Garima ◽  
Vincent Foulongne ◽  
Olivier Dereure ◽  
...  
Keyword(s):  
Tumor Cell ◽  
Cell Carcinoma ◽  
Merkel Cell Carcinoma ◽  
Circulating Tumor Cell ◽  
Cell Detection ◽  
Merkel Cell ◽  
Tumor Cell Detection

scholarly journals Clinical utility of a circulating tumor cell assay in Merkel cell carcinoma

2014 ◽  
Vol 70 (3) ◽  
pp. 449-455 ◽  
Author(s):  
Astrid Blom ◽  
Shailender Bhatia ◽  
Stephanie Pietromonaco ◽  
Karen Koehler ◽  
Jayasri G. Iyer ◽  
...  
Keyword(s):  
Tumor Cell ◽  
Cell Carcinoma ◽  
Merkel Cell Carcinoma ◽  
Clinical Utility ◽  
Circulating Tumor Cell ◽  
Merkel Cell ◽  
Cell Assay

scholarly journals Outcome of early stage Merkel carcinoma treated by exclusive radiation: a study of 53 patients

2021 ◽  
Vol 16 (1) ◽  
Author(s):  
Manon Dubois ◽  
Henry Abi Rached ◽  
Alexandre Escande ◽  
Frédéric Dezoteux ◽  
Franck Darloy ◽  
...  
Keyword(s):  
Cell Carcinoma ◽  
Merkel Cell Carcinoma ◽  
Early Stage ◽  
Cox Model ◽  
Combined Treatment ◽  
Disease Free Survival ◽  
External Beam Radiation ◽  
Merkel Cell ◽  
Beam Radiation ◽  
Metastatic Relapse

Abstract Purpose Early stage Merkel cell carcinoma (MCC) is a rare and aggressive primary skin cancer. The standard of care for MCC is broad excision and adjuvant external beam radiation therapy (EBRT). However, for some patients, anesthesia is contraindicated, while others run the risk of serious aesthetic sequelae. In such cases, exclusive radiotherapy is an interesting alternative to surgery. Though limited data is available, this study evaluates exclusive radiotherapy for MCC, using data from the largest retrospective study to date. Methods All patients who were followed in our center between 1989 and 2019 for histologically proven early stage MCC were included in the study. They were treated either by surgery with a 2-cm clear margin followed by adjuvant radiotherapy (RT) or by exclusive RT. Survival rates with adjuvant and exclusive EBRT were analyzed using Cox model and Fine and Gray model depending on the type of survival. p value < 0.05 was considered significant. Results Eighty-four patients treated for MCC were included. Fifty-three of them (63.1%) were treated by exclusive RT, and 31 (36.9%) had surgical excision followed by adjuvant RT. Local relapse rate was 13.7% (95% CI 8.0–43.7) in the RT monotherapy group (group A) and 25.8% (95% CI 10.3–56.2) in the surgery + RT group (group B) (p = 0.42). No statistical difference was found for nodal relapse (p = 0.81), metastatic relapse (p = 0.10), disease free survival (p = 0.83) or overall survival (p = 0.98). Conclusion Our study suggests that exclusive radiotherapy for early Merkel cell carcinoma leads to a similar oncological outcome as combined treatment, with fewer aesthetic sequelae. The approach is interesting for elderly patients with comorbidities or patients for whom surgery would cause significant functional or aesthetic sequelae.

scholarly journals Application of Novel Non-Thermal Physical Technologies to Degrade Mycotoxins

2021 ◽  
Vol 7 (5) ◽  
pp. 395
Author(s):  
Mohammad Yousefi ◽  
Masoud Aman Mohammadi ◽  
Maryam Zabihzadeh Khajavi ◽  
Ali Ehsani ◽  
Vladimír Scholtz
Keyword(s):  
Electron Beam ◽  
Food Systems ◽  
Large Scale ◽  
Plasma Electron ◽  
Pulsed Light ◽  
Beam Radiation ◽  
Practical Applications ◽  
Electron Beam Radiation ◽  
Non Thermal Plasma ◽  
Agriculture And Food

Mycotoxins cause adverse effects on human health. Therefore, it is of the utmost importance to confront them, particularly in agriculture and food systems. Non-thermal plasma, electron beam radiation, and pulsed light are possible novel non-thermal technologies offering promising results in degrading mycotoxins with potential for practical applications. In this paper, the available publications are reviewed—some of them report efficiency of more than 90%, sometimes almost 100%. The mechanisms of action, advantages, efficacy, limitations, and undesirable effects are reviewed and discussed. The first foretastes of plasma and electron beam application in the industry are in the developing stages, while pulsed light has not been employed in large-scale application yet.

One-step fabrication of photoluminescent SiC quantum dots through a radiation technique

2020 ◽  
Vol 44 (31) ◽  
pp. 13301-13307
Author(s):  
Wei Qi ◽  
Mengjie Li ◽  
Long Zhao
Keyword(s):  
Quantum Dots ◽  
Ionic Liquid ◽  
Electron Beam ◽  
Beam Radiation ◽  
Electron Beam Radiation ◽  
Radiation Technique ◽  
One Step

The fabrication of PL SiC-QDs by using ionic liquid-based microemulsions combined with electron beam radiation.

Effect of electron beam radiation dose on the foam formation in pre-ceramic polymer

2010 ◽  
Vol 79 (3) ◽  
pp. 301-305 ◽  
Author(s):  
Rosa Maria da Rocha ◽  
Esperidiana A.B. Moura ◽  
José Carlos Bressiani ◽  
Ana Helena A. Bressiani
Keyword(s):  
Electron Beam ◽  
Radiation Dose ◽  
Foam Formation ◽  
Beam Radiation ◽  
Electron Beam Radiation
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