scholarly journals Olfactory Discrimination in Adult Male Rats Undernourished during the Pre- and Neonatal Period

2012 ◽  
Vol 02 (03) ◽  
pp. 283-290 ◽  
Author(s):  
Mitzi G. Carreon ◽  
Carmen Torrero ◽  
Mirelta Regalado ◽  
Lorena Rubio ◽  
Manuel Salas
Keyword(s):  
Adult Male ◽  
Neonatal Period ◽  
Olfactory Discrimination ◽  
Male Rats

scholarly journals Postnatal Aromatase Blockade Increases c-fos mRNA Responses to Acute Restraint Stress in Adult Male Rats

Endocrinology ◽  
2012 ◽  
Vol 153 (4) ◽  
pp. 1603-1608 ◽  
Author(s):  
Brenda Bingham ◽  
Nancy X. R. Wang ◽  
Leyla Innala ◽  
Victor Viau
Keyword(s):  
Adult Male ◽  
Restraint Stress ◽  
Neonatal Period ◽  
Male Rats ◽  
Neural Pathways ◽  
Somatosensory Processing ◽  
Estrogen Exposure ◽  
Old Adult ◽  
Neuroendocrine Responses ◽  
Fos Expression

Recent evidence suggests that the aromatization of testosterone to estrogen is important for the organizing effects of neonatal testosterone on neuroendocrine responses to acute challenges. However, the extent to which neonatal inhibition of aromatase alters the stress-induced activation of neural pathways has not been examined. Here we assessed central patterns of c-fos mRNA induced by 30 min of restraint in 65-d-old adult male rats that were implanted with sc capsules of the aromatase inhibitor 1,4,6-androstatriene-3,17-dione (ATD), introduced within 12 h of birth and removed on d 21 of weaning. Neonatal ATD decreased the expression of arginine vasopressin within extrahypothalamic regions in adults, confirming reduced estrogen exposure during development. As adults, ATD-treated animals showed higher corticosterone responses at 30 min of restraint exposure compared with control animals as well as higher c-fos expression levels in the paraventricular nucleus of the hypothalamus. ATD treatment also increased stress-induced c-fos within several limbic regions of the forebrain, in addition to areas involved in somatosensory processing. Based on these results, we propose that the conversion of testosterone to estrogen during the neonatal period exerts marked, system-wide effects to organize adult neuroendocrine responses to homeostatic threat.

scholarly journals Neonatal administration of fluoxetine did not alter the anxiety indicators, but decreased the locomotor activity in adult rats in the elevated plus-maze

2008 ◽  
Vol 66 (4) ◽  
pp. 844-847 ◽  
Author(s):  
Valdenilson Ribeiro Ribas ◽  
Helena Karine Rufino Aniceto ◽  
Hugo André de Lima Martins ◽  
Ketlin Helenise dos Santos Ribas ◽  
Renata de Melo Guerra-Ribas ◽  
...  
Keyword(s):  
Locomotor Activity ◽  
Adult Male ◽  
Elevated Plus Maze ◽  
Neonatal Period ◽  
T Test ◽  
Male Rats ◽  
Adult Rats ◽  
Plus Maze ◽  
Neonatal Administration ◽  
Anxiety Index

The objective of this study was evaluate the anxiety and locomotor activity (LA) in 52 Wistar adult male rats, being 26 treated with fluoxetine (10 mg/Kg - sc) in the neonatal period. These same rats received foot shock (FS) (1.6-mA - 2-s) in the 90th day. The anxiety and LA were appraised by plus-maze. The time spent in the open arms was used as anxiety index and the LA was measured by number of entries in closed arms (NECA) and the total of entries (TE). T-test was used with p<0.05 and expresses data in mean±SEM. There were reductions with the fluoxetine group in the NECA (2.35±0.33) and in the TE (3.96±0.61) compared to the controls (4.65±0.52) and (6.96±0.94). The neonatal administration of fluoxetine did not alter the anxiety, but reduced the LA in the animals that received FS.

Subchronic co-administration to cadmium, diazinon and selenium causes apparent symptoms of osteoporosis in adult male rats

2014 ◽  
Author(s):  
Radoslav Omelka ◽  
Hana Chovancova ◽  
Ivana Bobonova ◽  
Grzegorz Formicki ◽  
Robert Toman ◽  
...  
Keyword(s):  
Adult Male ◽  
Male Rats

Corticosteroid secretion after the soy extract application to orchidectomized adult male rats

2018 ◽  
Author(s):  
Vladimir Ajdzanovic ◽  
Dragana Miljic ◽  
Natasa Ristic ◽  
Lazo Pendovski ◽  
Florina Percinic-Popovska ◽  
...  
Keyword(s):  
Adult Male ◽  
Male Rats ◽  
Corticosteroid Secretion

Effect of hemicastration on young and adult male rats

Reproduction ◽  
1972 ◽  
Vol 31 (3) ◽  
pp. 519-520 ◽  
Author(s):  
M. Hochereau-de Reviers ◽  
J Pelletier ◽  
M. de Reviers
Keyword(s):  
Adult Male ◽  
Male Rats
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