scholarly journals Pathophysiology and Treatment Options in Obstructive Sleep Apnoea: A Review of the Literature

2012 ◽  
Vol 03 (06) ◽  
pp. 473-484 ◽  
Author(s):  
Lars Rasmusson ◽  
Armin Bidarian ◽  
Lars Sennerby ◽  
Gareth Scott
Keyword(s):  
Obstructive Sleep Apnoea ◽  
Treatment Options ◽  
Sleep Apnoea ◽  
Review Of The Literature ◽  
Obstructive Sleep

Obstructive sleep apnoea and schizophrenia: a primer for psychiatrists

2011 ◽  
Vol 23 (5) ◽  
pp. 201-209 ◽  
Author(s):  
Abdulkader Alam ◽  
Kadiamada Nanaiah Roy Chengappa
Keyword(s):  
Obstructive Sleep Apnoea ◽  
Daytime Sleepiness ◽  
Treatment Options ◽  
Clinical Manifestations ◽  
Sleep Apnoea ◽  
Diagnosis And Treatment ◽  
Adverse Health Outcomes ◽  
Ovid Medline ◽  
Obstructive Sleep ◽  
Osa Treatment

Alam A, Chengappa KNR. Obstructive sleep apnoea and schizophrenia: a primer for psychiatristsObjective:The main objective of this review is to improve psychiatric clinician awareness of obstructive sleep apnoea (OSA) and its potential consequences in patients with schizophrenia. This article will also discuss the diagnosis and treatment options for OSA while considering the significant role psychiatrists can play in facilitating the diagnosis and treatment of OSA.Data sources:Ovid, Medline and PsychInfo databases were searched for articles between 1960 and 2010. Search terms used wereSleep apnoeaorapnoeaandschizophreniaorpsychosis. The number of articles retrieved was 38. Articles were carefully reviewed for any data pertinent to OSA in patients with schizophrenia.Conclusions:OSA is a common disorder that is frequently unrecognised. As a chronic breathing condition, OSA is associated with adverse health outcomes and high mortality. OSA may co-occur with schizophrenia or evolve over time, especially with weight gain. The diagnosis should be considered whenever a patient presents with risk factors or clinical manifestations that are highly suggestive of OSA. Those who report snoring, daytime sleepiness and are obese or have a large neck circumference should be considered for an OSA diagnosis. Appropriate diagnosis and treatment of OSA can reduce daytime sleepiness, improve cardiovascular and other medical conditions, as well as reduce mortality. Psychiatrists can play very important role in suspecting OSA in their patients and making the initial referral. Furthermore, behavioural management, especially promoting weight loss and smoking cessation, are effective components of OSA treatment that psychiatrists are positioned to facilitate with their patients.

Obstructive sleep apnoea

2021 ◽  
pp. 335-344
Author(s):  
Terry Robinson ◽  
Jane Scullion
Keyword(s):  
Obstructive Sleep Apnoea ◽  
Nursing Care ◽  
Treatment Options ◽  
Signs And Symptoms ◽  
Diagnostic Procedures ◽  
Sleep Apnoea ◽  
Differential Diagnoses ◽  
Treatment Prevalence ◽  
Obstructive Sleep ◽  
Psychosocial History

This chapter covers the causes, signs, and symptoms of obstructive sleep apnoea (OSA). It explains the process of diagnosis, from a history, medications, family, and psychosocial history, occupation, and diagnostic procedures. Differential diagnoses that should be excluded are listed. The prevalence of OSA is estimated to be around 4% of the population. It is quite a common disorder, although this figure may be an underestimate as many people may not seek treatment. Prevalence figures also vary according to the chosen threshold for defining a significant sleep abnormality and symptoms. Treatment options are also outlined, and the specific aspects of nursing care are listed.

scholarly journals Personalised medicine in sleep respiratory disorders: focus on obstructive sleep apnoea diagnosis and treatment

2017 ◽  
Vol 26 (146) ◽  
pp. 170069 ◽  
Author(s):  
Maria R. Bonsignore ◽  
Monique C. Suarez Giron ◽  
Oreste Marrone ◽  
Alessandra Castrogiovanni ◽  
Josep M. Montserrat
Keyword(s):  
Obstructive Sleep Apnoea ◽  
Treatment Options ◽  
Personalised Medicine ◽  
Upper Airway ◽  
Sleep Apnoea ◽  
Lifestyle Changes ◽  
Mandibular Advancement ◽  
Considerable Proportion ◽  
Special Focus ◽  
Obstructive Sleep

In all fields of medicine, major efforts are currently dedicated to improve the clinical, physiological and therapeutic understanding of disease, and obstructive sleep apnoea (OSA) is no exception. The personalised medicine approach is relevant for OSA, given its complex pathophysiology and variable clinical presentation, the interactions with comorbid conditions and its possible contribution to poor outcomes. Treatment with continuous positive airway pressure (CPAP) is effective, but CPAP is poorly tolerated or not accepted in a considerable proportion of OSA patients. This review summarises the available studies on the physiological phenotypes of upper airway response to obstruction during sleep, and the clinical presentations of OSA (phenotypes and clusters) with a special focus on our changing attitudes towards approaches to treatment. Such major efforts are likely to change and expand treatment options for OSA beyond the most common current choices (i.e. CPAP, mandibular advancement devices, positional treatment, lifestyle changes or upper airway surgery). More importantly, treatment for OSA may become more effective, being tailored to each patient's need.

scholarly journals Challenges in Diagnosing and Treating Obstructive Sleep Apnoea in Children

2018 ◽  
Vol 4 (1) ◽  
pp. 23
Author(s):  
Refika Ersu ◽  
Keyword(s):  
Obstructive Sleep Apnoea ◽  
Treatment Options ◽  
Combined Treatment ◽  
Sleep Apnoea ◽  
Treatment Modalities ◽  
Obstructive Sleep ◽  
Respiratory Polygraphy ◽  
Weight Loss Interventions ◽  
Multiple Health ◽  
Prompt Diagnosis

Prompt diagnosis and treatment of obstructive sleep apnoea in children is essential to prevent multiple health consequences, but distinctive symptoms are scarce. While overnight polysomnography is the standard diagnostic tool, it is not widely available. Nocturnal oximetry, respiratory polygraphy and standardised questionnaires are useful alternatives. Treatment options include positive airway pressure, weight loss interventions and anti-inflammatory treatment with nasal corticosteroids and/or oral montelukast. Combined treatment modalities may improve outcomes.

Paediatric obstructive sleep apnoea: is our operative management evidence-based?

2018 ◽  
Vol 132 (4) ◽  
pp. 293-298 ◽  
Author(s):  
L Pabla ◽  
J Duffin ◽  
L Flood ◽  
K Blackmore
Keyword(s):  
Surgical Treatment ◽  
Obstructive Sleep Apnoea ◽  
Treatment Options ◽  
Operative Management ◽  
Evidence Base ◽  
Sleep Apnoea ◽  
Surgical Correction ◽  
Operative Care ◽  
Obstructive Sleep ◽  
Objective Evidence

AbstractBackground:Despite the plethora of publications on the subject of paediatric obstructive sleep apnoea, there seems to be wide variability in the literature and in practice, regarding recourse to surgery, the operation chosen, the benefits gained and post-operative management. This may reflect a lack of high-level evidence.Methods:A systematic review of four significant controversies in paediatric ENT was conducted from the available literature: tonsillectomy versus tonsillotomy, focusing on the evidence base for each; anaesthetic considerations in paediatric obstructive sleep apnoea surgery; the objective evidence for the benefits of surgical treatment for obstructive sleep apnoea; and the medical treatment options for residual obstructive sleep apnoea after surgical treatment.Results and conclusion:There are many gaps in the evidence base for the surgical correction of obstructive sleep apnoea. There is emerging evidence favouring subtotal tonsillectomy. There is continuing uncertainty around the prediction of the level of post-operative care that any individual child might require. The long-term benefit of surgical correction is a particularly fertile ground for further research.

scholarly journals The Management of Co-Morbidities in Patients with Heart Failure – Obstructive Sleep Apnoea

2017 ◽  
Vol 10 ◽  
Author(s):  
Andrew Coats
Keyword(s):  
Heart Failure ◽  
Obstructive Sleep Apnoea ◽  
Adult Population ◽  
Treatment Options ◽  
Sleep Apnoea ◽  
Response To Treatment ◽  
Consensus Recommendation ◽  
Sleep Study ◽  
Obstructive Sleep ◽  
Artery Disease

Heart failure (HF) patients are older and frequently present with multiple co-morbidities. Co- morbidities worsen patient symptoms and may contribute to the progression of heart failure, increase mortality or limit the therapeutic response to treatment. Obstructive sleep apnoea (OSA) affects 2–4% of the adult population world-wide and is associated with similar risk factors to HF, meaning it is a frequent finding in HF patients, including HFrEF, HFmrEF and HFpEF. OSA has consistently been shown to be associated with hypertension, coronary artery disease, arrhythmias, heart failure, and stroke. A thorough understanding of the diagnosis and treatment options of OSA is of paramount importance to the practising HF clinician. Patients may present to the HF specialist having been diagnosed by a formal sleep study or may be suspected of OSA because of symptoms of snoring, reports of obstructed breathing by the sleep partner or day-time sleepiness. The mainstay of treatment for OSA is a positive airway pressure mask which can be used in mild moderate and severe OSA. The need for therapy should be discussed with the patient and if the AHI is above 15/hr then treatment is indicated to reduce this to below 15. This is a consensus recommendation and no adequately powered clinical trials have shown this improves either mortality or the risk of disease progression. Other options are discussed

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