scholarly journals Development of Hormone-Active Fiber in the Form of Artificial Insulin Depot

Engineering ◽  
2012 ◽  
Vol 04 (10) ◽  
pp. 189-191
Author(s):  
A. Medovic Baralic ◽  
P. Skundric ◽  
Lj. Sretkovic ◽  
I. Pajic Lijakovic ◽  
M. Kostic
2019 ◽  
Vol 19 (1) ◽  
pp. 12-19 ◽  
Author(s):  
Harsha Kashyap ◽  
Sarika Gupta ◽  
Renu Bist

Diabetes is a metabolic hyperglycemic condition that progressively develops, effect small and large sensory fibers in the affected population. It has various complications as hypertension, coronary artery disease, stroke, blindness, kidney disease as well as peripheral neuropathy. Sulfonylureas, thiazolidinediones, metformin, biguanidine, acarbose and insulin are commonly used drugs for diabetic patients, but these all have certain side effects. Even metformin, that is known as the miracle drug for diabetes has been found to be associated with side effects, as during treatment it involves complications with eyes, kidneys, peripheral nerves, heart and vasculature. In the present article, we hypothesize recent discoveries with respect to active ingredients from Indian medicinal plants i.e., polypeptide-p (protein analogue act as artificial insulin), charantin (a steroidal saponin), momordicin (an alkaloid) and osmotin (ubiquitous plant protein and animal analogue of human adeponectin) possessing anti-hyperglycemic potential for diabetes type II. Therefore, plants as herbal therapy have preventive care of hyperglycemia accompanied with healthy lifestyle which can provide significant decline in the incidences of diabetes in future.


2014 ◽  
Vol 22 (9) ◽  
pp. 11244 ◽  
Author(s):  
Yanjie Zhao ◽  
Jun Chang ◽  
Jiasheng Ni ◽  
Qingpu Wang ◽  
Tongyu Liu ◽  
...  

2007 ◽  
Vol 19 (5) ◽  
pp. 255-257 ◽  
Author(s):  
Michael Buric ◽  
Kevin P. Chen ◽  
Matrika Bhattarai ◽  
Philip R. Swinehart ◽  
Mokhtar Maklad

2021 ◽  
Vol 29 (5) ◽  
pp. 7024
Author(s):  
Vitaly Wirthl ◽  
Lothar Maisenbacher ◽  
Johannes Weitenberg ◽  
Alexander Hertlein ◽  
Alexey Grinin ◽  
...  

2009 ◽  
Vol 14 (1) ◽  
pp. 41-49
Author(s):  
V. Kleiza ◽  
J. Verkelis

Regularities of variation of output signal U of one reflection fiber optopair dependent on the distance h between active fiber tips and light reflecting body-mirror (U-h characteristics) and on the angle 2θ between the FAT axes, the distance between FAT being minimal (b = bmin), have been explored by modelling and experimentally. The parameters of U-h characteristics have been established: maximal sensitivity Smax(h), localization and values of maxima and inflection points (+,−) of a function U(h), length of interval ∆h in which the output signal U(h) is linear (98 % of sensitivity maxima), as well as dependences of these parameters on the angle θ and distance h. It has been shown that the experimental results are well described by the formulas improved by the authors previously. It has been demonstrated that reflection fiber optopair sensitivity Smax to displacement considerably increases with an increase of the angle θ. It has been defined that, with an increase of the angle θ up to 20°, sensitivity increases up to 30 times when active fiber tips axes are almost parallel and the diameter of the fiber core is 100 µm, and 125 µm with cladding. Apart from that, Smax increases almost exponentially up to θ = 20°. A drawback of such an RFP is that with an increase of the angle θ, the size of the sensor head also increases. However, due to their considerably increased sensitivity, they can be and are wide used.


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