scholarly journals Microchip Electrode Development for Traveling wave Dielectrophoresis of Non-Spherical Cell Suspensions

Engineering ◽  
2012 ◽  
Vol 04 (10) ◽  
pp. 88-93 ◽  
Author(s):  
Sakshin Bunthawin ◽  
Jatuporn Kongklaew ◽  
Adisorn Tuantranont ◽  
Kata Jaruwongrangsri ◽  
Thitima Maturos
Keyword(s):  
Traveling Wave ◽  
Cell Suspensions ◽  
Spherical Cell ◽  
Traveling Wave Dielectrophoresis

scholarly journals DNA-induced changes in traveling wave dielectrophoresis velocity of microparticles

AIP Advances ◽  
2020 ◽  
Vol 10 (1) ◽  
pp. 015236 ◽  
Author(s):  
Michihiko Nakano ◽  
Zhenhao Ding ◽  
Masafumi Inaba ◽  
Junya Suehiro
Keyword(s):  
Traveling Wave ◽  
Induced Changes ◽  
Traveling Wave Dielectrophoresis

Separation and Manipulation of Particles Using Traveling Wave Dielectrophoretic Force

2009 ◽  
Vol 74 ◽  
pp. 219-222
Author(s):  
Thitima Maturos ◽  
Kata Jaruwongrangsee ◽  
Assawapong Sappat ◽  
Tanom Lomas ◽  
Anurat Wisitsoraat ◽  
...  
Keyword(s):  
Red Blood Cells ◽  
Applied Voltage ◽  
Traveling Wave ◽  
Blood Cells ◽  
Electrode Array ◽  
Travelling Wave ◽  
Cell Manipulation ◽  
Mixed Solution ◽  
Traveling Wave Dielectrophoresis ◽  
Parallel Electrode

In this work, we present a device for cell manipulation and separation by using travelling wave dielectophoretic force. The device consists of a 16 parallel electrode array and microchamber. The dielectrophoretic PDMS chamber was fabricated by using standard microfabrication techniques. The Cr/Au parallel electrode array of 100 µm wide and 300 nm thick was patterned on a glass slide by sputtering through microshadow mask. The polystyrene microspheres suspension in de-ionized water and red blood cells in D-mannitol solution were used as tested cells. Cells respond to the electric field in various mechanisms depending on the applied voltage and frequency of the AC signals. For 4.5 µm polystyrene, the traveling wave dielectrophoresis happened when the applied voltage was 10 V, and the frequency of the applied signals was in the range of 50 kHz-700 kHz. For 10 µm polystyrene the twDEP occurred when the applied voltage was 7 V, and frequency was in the range 30 kHz-1MHz. While the red blood cells experienced the twDEP when the applied voltage was 3 V and frequency was in the range 50 kHz-2MHz. The mixed solution containing equal amount of 4.5 and 10 µm microspheres were used for separation test. The big microspheres were moved under twDEP force when the applied voltage was 7 V, and the frequency was in the range of 25 kHz-1MHz while the small microspheres were attached to the electrodes. Therefore, the twDEP device can manipulate and separate the microspheres with different sizes, and it can be further applied for cells selection.

Joint Use of Traveling Wave Dielectrophoresis and AC-Electroosmosis for Particle Manipulation

2009 ◽  
Author(s):  
Sophie Loire ◽  
Igor Mezic
Keyword(s):  
Fluid Flow ◽  
Traveling Wave ◽  
Rectangular Channel ◽  
Low Frequency ◽  
Joint Effect ◽  
Electrode Arrays ◽  
Ac Electroosmosis ◽  
Phase Signal ◽  
Output Concentration ◽  
Traveling Wave Dielectrophoresis

Joint effect of traveling wave dielectrophoresis and AC electroosmotic fluid flow is used to sort bacteria from other particles and increase the bacteria output concentration in a microfluidic device. The device consists of a thin and long rectangular channel with two interdigitated electrode arrays, one at the bottom and one at the top of the channel, that are used to generate a nonuniform electric field. A four-phase signal at high frequency superposed on a low frequency signal is applied. At the end of the channel, the fluid is collected in two outputs: the bacteria are collected on one side and fluid without bacteria is collected on the other side. We have previously demonstrated a method to optimize cell separation using multiple frequency dielectrophoresis. The device presented here illustrates a novel use of multiple frequencies that permits the combined use of traveling wave dielectrophoresis and AC electroosmotic fluid flow.

Sign in / Sign up

Export Citation Format

Share Document