Infective Endocarditis in Tetralogy of Fallot Complicating Brain Abscess—A Case Report

Streptococcus acidominimus is rarely pathogenic in humans and is usually detected in veterinary science. In the literature, there are approximately 20 case reports that Streptococcus acidominimus is a human pathogen. They are pneumonia, pericarditis, infective endocarditis, sepsis, brain abscess and gradienigo syndrome. Only two of these cases were in the pediatric age group, one was infective endocarditis at the age of 15 years, other one was otitis media and gradenigo syndrome at the age of 12 years. There are no cases of invasive infection due to Streptococcus acidominimus in Turkey. Here, we report a case of infective endocarditis caused by Streptococcus acidominimus at 14 years of age.

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Native Valve Infective Endocarditis with Osteomyelitis and Brain Abscess Caused by Granulicatella adiacens with Literature Review

Case Reports in Infectious Diseases ◽

10.1155/2019/4962392 ◽

2019 ◽

Vol 2019 ◽

pp. 1-6

Author(s):

Sachin M. Patil ◽

Niraj Arora ◽

Peter Nilsson ◽

S. J. Yasar ◽

Dima Dandachi ◽

...

Keyword(s):

Case Report ◽

Infective Endocarditis ◽

Mitral Valve ◽

Literature Review ◽

Brain Abscess ◽

Antimicrobial Susceptibility ◽

First Case ◽

Tertiary Center ◽

Granulicatella Adiacens ◽

Susceptibility Patterns

Granulicatella adiacens is a type of NVS (nutritionally variant streptococci) rarely causing infective endocarditis (IE). NVS are fastidious and unable to sustain growth on routine culture media due to lack of specific nutrients. Endocarditis caused by NVS due to their virulence is associated with higher treatment failures and mortality rates. New antimicrobial susceptibility patterns are indicative of a significant rise in penicillin resistance and susceptibility differences between NVS subspecies. Initial empirical therapy is essential as a delay in using the appropriate agent leads to poor results. We present a case of an immunocompetent young female with recent intravenous drug abuse resulting in native mitral valve endocarditis with ruptured chordae tendineae and septic embolization, causing brain abscess and lumbar spine osteomyelitis. She was transferred to a tertiary center where she underwent mitral valve replacement successfully and treated with six weeks of intravenous vancomycin and ertapenem. To our knowledge, ours is the first case report of G. adiacens endocarditis in an adult with brain abscess and osteomyelitis with an excellent response to antibiotic therapy. Based on our case report, literature review, and new antimicrobial susceptibility patterns, updates to treatment guidelines are suggested to improve the therapeutic outcomes.

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Subacute Infective Endocarditis in a Child Due to Streptococcus acidominimus: a Case Report

Çocuk Enfeksiyon Dergisi/Journal of Pediatric Infection ◽

10.5578/ced.69431 ◽

2020 ◽

Vol 54 (4) ◽

pp. 244-246

Author(s):

Ayşe Sülü ◽

Ümmühan Çay ◽

Hikmet Öztel Ocak

Keyword(s):

Case Report ◽

Infective Endocarditis ◽

Brain Abscess ◽

Case Reports ◽

Invasive Infection ◽

Age Group ◽

Pediatric Age ◽

Veterinary Science ◽

Human Pathogen ◽

Pediatric Age Group

Streptococcus acidominimus is rarely pathogenic in humans and is usually detected in veterinary science. In the literature, there are approximately 20 case reports that Streptococcus acidominimus is a human pathogen. They are pneumonia, pericarditis, infective endocarditis, sepsis, brain abscess and gradienigo syndrome. Only two of these cases were in the pediatric age group, one was infective endocarditis at the age of 15 years, other one was otitis media and gradenigo syndrome at the age of 12 years. There are no cases of invasive infection due to Streptococcus acidominimus in Turkey. Here, we report a case of infective endocarditis caused by Streptococcus acidominimus at 14 years of age.

Download Full-text