scholarly journals Relationship between Self-Reported Vaccination History and Measles and Rubella Antibody Titers in Medical and Nursing Students

2017 ◽  
Vol 07 (02) ◽  
pp. 27-36
Author(s):  
Masanori Ogawa ◽  
Ryusuke Ae ◽  
Teppei Sasahara
Keyword(s):  
Nursing Students ◽  
Vaccination History ◽  
Antibody Titers ◽  
Rubella Antibody

scholarly journals Hepatitis B antibody titers in Indonesian adolescents who received the primary hepatitis B vaccine during infancy

2013 ◽  
Vol 53 (3) ◽  
pp. 160
Author(s):  
Hartono Gunardi ◽  
Adra Firmansyah ◽  
Sri Rezeki S Harun ◽  
Sudigdo Sastroasmoro
Keyword(s):  
Hepatitis B ◽  
Booster Dose ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional ◽  
Blood Tests ◽  
Vaccination History ◽  
Antibody Titers ◽  
Hb Vaccine ◽  
Over Time

Backgi-ound Hepatitis B (HB) has been classified as moderate-tohighlyendemic in Indonesia. HB vaccination, the most effectivemethod to prevent HB viral transmission, induces protectiveantibodies against HB surface antigen (anti-HBs). However, theseantibodies decline in titer over time. Studies on the duration ofprotection and the prevalence of n on-responders in Indonesianadolescents have been limited.Objectives To determine anti-HBs titers in 15-17-year oldIndonesian adolescents given primary HB vaccine during infancyand the prevalence of non-responders after a HB vaccine boosterdosage.Methods This cross-sectional study was performed from Februaryto September 2008 on adolescents aged 15-17 years in threesenior high schools in Jakarta who received complete primary HBvaccines during infancy, based on parents' recall. Investigationsincluded HB vaccination history, anthropometric measurements,and blood tests for anti-HBs before and 4-6 weeks after a boosterdose ofHB vaccine.Results Of 94 subjects, 35 had protective anti-HBs and 59 hadundetectable anti-HBs. A booster dose was administered to 5 8 of then on-protected subjects, of which 33 showed anamnestic responses.However, 25 subjects failed to generate protective anti-HBs. Takinginto consideration the adolescents with protective anti-HBs beforeand after the booster dose, serologic protection was demonstratedin 73%. Non-responder prevalence was 27%. The high prevalenceof non-responders may indicate bias of parents' recall.Conclusion Protective anti-HBs is detected in less than half ofIndonesian adolescents given primary HB vaccine during infancy.Following booster dosage, anamnestic responses are n oted in onethirdof subjects. The prevalence of non-responders is 27%, butconfirmation with further study is needed.

The Effect of Influenza Vaccination History on Changes in Hemagglutination Inhibition Titers After Receipt of the 2015–2016 Influenza Vaccine in Older Adults in Hong Kong

2019 ◽  
Vol 221 (1) ◽  
pp. 33-41 ◽  
Author(s):  
Tiffany W Y Ng ◽  
Ranawaka A P M Perera ◽  
Vicky J Fang ◽  
Emily M Yau ◽  
J S Malik Peiris ◽  
...  
Keyword(s):  
Older Adults ◽  
Hong Kong ◽  
Influenza Vaccine ◽  
Influenza Vaccination ◽  
Hemagglutination Inhibition ◽  
Age Groups ◽  
Antibody Responses ◽  
Serum Samples ◽  
Vaccination History ◽  
Antibody Titers

Abstract Background Immune responses to influenza vaccination can be weaker in older adults than in other age groups. We hypothesized that antibody responses would be particularly weak among repeat vaccinees when the current and prior season vaccine components are the same. Methods An observational study was conducted among 827 older adults (aged ≥75 years) in Hong Kong. Serum samples were collected immediately before and 1 month after receipt of the 2015–2016 quadrivalent inactivated influenza vaccine. We measured antibody titers with the hemagglutination inhibition assay and compared the mean fold rise from prevaccination to postvaccination titers and the proportions with postvaccination titers ≥40 or ≥160. Results Participants who reported receipt of vaccination during either of the previous 2 years had a lower mean fold rise against all strains than with those who did not. Mean fold rises for A(H3N2) and B/Yamagata were particularly weak after repeated vaccination with the same vaccine strain, but we did not generally find significant differences in the proportions of participants with postvaccination titers ≥40 and ≥160. Conclusions Overall, we found that reduced antibody responses in repeat vaccinees were particularly reduced among older adults who had received vaccination against the same strains in preceding years.

scholarly journals CARE FOR PATIENTS WITH ACCIDENTAL TETANUS THROUGH FIREWORKS: EXPERIENCE REPORT

2020 ◽  
Vol 6 ◽  
Author(s):  
Gessica Louzada Caires ◽  
Laurena Shirlei Fraga dos Reis ◽  
Elaine De Oliveira Souza Fonseca ◽  
Ricardo Bruno Santos Ferreira
Keyword(s):  
Nursing Students ◽  
Data Collection ◽  
Clinical Picture ◽  
Public Hospital ◽  
Descriptive Study ◽  
Experience Report ◽  
Detailed Data ◽  
Emergency Unit ◽  
Study Experience ◽  
Vaccination History

Objective: To report the experience of a care for a person with clinical picture of accidental tetanus, victim of fireworks. Method: It is a descriptive study, experience report type, referring to the experience of a care performed by nursing students in June 2019, in an emergency unit at a regional public hospital in a city in the inland of state of Bahia, Brazil. Results: Victims of burns by fireworks need nursing actions that promote measures to prevent accidental tetanus. These activities can be a detailed data collection, such as observation of vaccination history and wound bed care. Conclusion: From the experience, it was possible to expand the knowledge of nursing students through reflections on the immediate measures related to care with accidental tetanus.

RUBELLA ANTIBODY DETERMINATIONS

PEDIATRICS ◽  
1967 ◽  
Vol 40 (5) ◽  
pp. 789-797
Author(s):  
John L. Sever ◽  
David A. Fuccillo ◽  
Gary L. Gitnick ◽  
Robert J. Huebner ◽  
Mary Ruth Gilkeson ◽  
...  
Keyword(s):  
Young Adults ◽  
Close Agreement ◽  
Gamma Globulin ◽  
Complement Fixation ◽  
Rapid Development ◽  
False Negative ◽  
Complete Agreement ◽  
Congenital Rubella ◽  
Antibody Titers ◽  
Rubella Antibody

Four methods were used to determine rubella antibody titers in patients with acquired and congenital rubella and in gamma-globulin. These methods include hemagglutination inhibition (HI), neutralization (Neut), fluorescence (FA), and complement fixation (CF). With acquired rubella, all four methods showed a rapid development of antibody shortly after the occurrence of rash. Maximum titers appeared within a few weeks, following which HI and CF titers began to decrease and the FA tests showed a weakening of fluorescence. HI titers were four- to sixteenfold higher than Neut, FA, and CF levels. Ten or 20 years after rubella, HI, Neut, and FA tests continued to show detectable antibody but half of the patients no longer had CF antibody. HI titers were still higher than Neut and FA but were considerably lower than convalescent levels. There was complete agreement between HI and Neut tests in the detection of antibody in young adults. For congenital rubella, HI, Neut, and FA antibody persisted in the affected children at least through adolescence. HI and CF antibody increased occasionally during the period 8 to 12 months after birth. Gamma-globulin titers with the HI and Neut methods were in close agreement. Convalescent rubella gamma-globulin gave titers two- to fourfold higher than standard commercial gamma-globulin. Variations in the HA and HI tests were caused by modification of the method of treatment of the antigen, the concentration of red cells used, the size of the test (macro versus micro), the pH of the test, and the treatment of sera. The most significant effects were related to the treatment used to eliminate nonspecific inhibitors in the sera. Improper treatment can give false negative or false positive tests. When properly performed and appropriately controlled, the HI test gives results essentially identical to the Neut method, although the titers are consistently higher than the Neut test. This new method, then, is rapid and convenient for obtaining reliable information on the antibody status and susceptibility of patients.

Comparative Cohort Epidemiological Study of Collective Immunity against New Coronavirus Infection among Different Groups of Military Personnel

2021 ◽  
Vol 76 (6) ◽  
pp. 661-668
Author(s):  
Evgenij V. Kryukov ◽  
Dmitrij V. Trishkin ◽  
Andrej M. Ivanov ◽  
Dmitrii V. Ovchinnikov ◽  
Aleksandr A. Kuzin ◽  
...  
Keyword(s):  
Epidemiological Study ◽  
Solid Phase ◽  
Total Sample ◽  
Blood Groups ◽  
Educational Organizations ◽  
Epidemic Process ◽  
Population Immunity ◽  
Vaccination History ◽  
Antibody Titers ◽  
First Time

Background. The need to study the population immunity to the SARS-CoV-2 virus is due to the intensive spread of COVID-19 and the implementation of immunoprophylaxis of this infection. The identification of the features of the formation of immunoresistance in organized military collectives will allow us to predict the development of the epidemic situation, including among comparable population groups. Aims the study of population immunity to the SARS-CoV-2 virus in the context of the COVID-19 pandemic against the background of specific immunoprophylaxis in organized military collectives. Methods. According to epidemiological indications, an epidemiological study of collective immunity to the SARS-CoV-2 virus was conducted against the background of vaccination among cadets of military educational organizations. The study involved 497 people, divided into groups by epidemiological and vaccination history for COVID-19, blood groups and Rh factor. The assessment of the immunity intensity was carried out by the levels of class G immunoglobulins (IgG) to SARS-CoV-2 in the blood serum by the method of solid-phase enzyme immunoassay. Results. Seroprevalence in the total sample was 92.6%. The highest rates were observed among vaccinated patients: those who were not ill and vaccinated 99.0 0.7%, those who were ill and vaccinated-100% (mean geometric antibody titers 1:2234 and 1:4399). Among the ill, unvaccinated individuals, the seroprevalence index was 84.5 3.2% (1:220). Among those who were not ill, not vaccinated 8.2 3.1% (1:113), which may indicate a hidden course of the epidemic process in the team. A negative immune response was more common (tSt = 2.01; p 0.05) in individuals A(II)Rh+ blood group. The highest proportion of maximum antibody titers (1:32001:6400) was determined in AB(IV) individuals. Rh-blood groups (tSt=2.21; p 0.05). Conclusions. For the first time, the formation of combined immunity with the highest concentrations of specific antibodies was revealed in patients who have been ill and vaccinated has been revealed, which allows us to recommend vaccination to those who have suffered from COVID-19. The emergence of post-infectious immunity in organized groups with a latent epidemic process has been established. The relationship between the intensity of immunity with blood groups and the Rh factor was found.

Congenital Rubella Syndrome: A Case Report on Changes in Viral Load and Rubella Antibody Titers

PEDIATRICS ◽  
2016 ◽  
Vol 137 (5) ◽  
pp. e20153333-e20153333 ◽  
Author(s):  
K. Nagasawa ◽  
N. Ishiwada ◽  
A. Ogura ◽  
T. Ogawa ◽  
N. Takeuchi ◽  
...  
Keyword(s):  
Case Report ◽  
Viral Load ◽  
Congenital Rubella Syndrome ◽  
Congenital Rubella ◽  
Antibody Titers ◽  
Rubella Antibody

Medical and Nursing Students with Suboptimal Protective Immunity against Vaccine-Preventable Diseases

2009 ◽  
Vol 30 (10) ◽  
pp. 1006-1011 ◽  
Author(s):  
Ioanna D. Pavlopoulou ◽  
George L. Daikos ◽  
Andreas Tzivaras ◽  
Evangelos Bozas ◽  
Chris Kosmidis ◽  
...  
Keyword(s):  
Nursing Students ◽  
Hepatitis B ◽  
Hepatitis A ◽  
Hepatitis A Virus ◽  
Hospital Setting ◽  
Vaccine Preventable Diseases ◽  
Healthcare Students ◽  
B Virus ◽  
Vaccination History ◽  
History Of

Objectives.Medical and nursing students (hereafter referred to as “healthcare students”) are at risk of contracting and transmitting infectious diseases in a hospital Setting. The aim of our study was to evaluate the vaccination history of healthcare students and their serologic immunity against vaccine-preventable diseases.Design.Prospective cohort study.Setting.A tertiary care children's hospital in Athens, Greece, which is affiliated with the University of Athens.Methods.Healthcare students were recruited during April through November 2007. The information obtained from these students during personal interviews included demographics and whether there was a history of varicella, measles, mumps, rubella, and/or hepatitis A or B virus infection. Vaccination history and documentation of disease were abstracted from available medical records. Serum antibodies against the above-mentioned viral agents were determined by use of an enzyme-linked immunosorbent assay. Seronegative students and those with immunization gaps were referred to local vaccination clinics, and compliance was assessed 3 months later.Results.A total of 187 healthcare students were recruited, 131 (70.1%) of whom provided complete documentation of vaccination history. Adequate immunity against diphtheria and tetanus was documented for 55 (37.2%) and 73 (49.3%) of the 148 participants, respectively, whereas age-appropriate vaccination against pertussis, diphtheria, tetanus, and poliomyelitis was noted for 138 (93.2%), 147 (99.3%), 147 (99.3%), and 147 (99.3%) healthcare students, respectively. Of 185 healthcare students, 171 (92.4%) were immune to varicella. Of 182 healthcare students, 179 (98.4%) were immune to measles, 163 (89.6%) were immune to mumps, and 176 (96.7%) were immune to rubella. Of 179 healthcare students, 151 (84.4%) were immune to hepatitis B virus. Of 178 healthcare students, 26 (14.6%) were immune to hepatitis A virus. Antibodies (10 IU/L or higher) to hepatitis B surface antigen were detected for 151 (84.4%) of 179 healthcare students, and antibodies (10 IU/L or higher) to hepatitis A virus were detected for 26 (14.6%) of 178 healthcare students. Fewer than 30% of participants were in full compliance with recommended vaccinations.Conclusions.We have determined that there is a certain proportion of healthcare students who are susceptible to certain vaccine-preventable diseases. The development of an appropriate vaccination strategy is required to decrease the risk of transmission in a hospital setting.

A circannual rhythm in rubella antibody titers

1982 ◽  
Vol 13 (1) ◽  
pp. 81-88 ◽  
Author(s):  
Leon S. Rosenblatt ◽  
Moshe Shifrine ◽  
Norriss W. Hetherington ◽  
Theresa Paglierioni ◽  
Malcolm R. MacKenzie
Keyword(s):  
Circannual Rhythm ◽  
Antibody Titers ◽  
Rubella Antibody
Sign in / Sign up

Export Citation Format

Share Document