scholarly journals Syntheses, Characterization and Biological Activity of Novel Thiazoylazo Dye and Its Coordination Compounds

2021 ◽  
Vol 11 (05) ◽  
pp. 179-205
Author(s):  
Temitayo O. Aiyelabola
2016 ◽  
Vol 45 (29) ◽  
pp. 11849-11863 ◽  
Author(s):  
Upendarrao Golla ◽  
Amit Adhikary ◽  
Amit Kumar Mondal ◽  
Raghuvir Singh Tomar ◽  
Sanjit Konar

Three double stranded helicates and one linear chain compound have been synthesized following similar synthetic strategy with change in the coordination of the ligands. Magnetic studies, nuclease activity and cytotoxicity on mammalian cancer cell lines have been investigated.


2020 ◽  
Vol 71 (4) ◽  
pp. 336-346
Author(s):  
Mirela Calinescu ◽  
Ovidiu Oprea ◽  
Catalina Stoica ◽  
Mihai Nita-Lazar ◽  
Madalina Mihalache

Four coordination compounds of Pd(II), Pt(II) and Pt(IV) with usnic acid (H3AU) and 1-(o-tolyl)biguanide (TB) as ligands have been synthesized in view of their potential as antimicrobial, antifungal and antitumor agents. The metal complexes have been characterized by elemental and thermogravimetrical analyses, infrared and electronic spectra. Based on these studies, the following formulas have been proposed for the complexes: [Pd(TB)(H3AU)]PdCl4 (C1), [Pd(TB)(H2AU)] CH3COO (C2), [Pt(TB)(H2AU)Cl2]Cl (C3) and [Pt(TB)(H2AU)]Cl (C4), where H2AU is deprotonated usnic acid. The in vitro biological activities of the new complexes were tested against Staphylococcus aureus ATCC 25923, Pseudomonas aeruginosa ATCC 27853, Candida albicans ATCC 10231 and HeLa tumor cells. All complexes were found to have good biological properties and therefore they can be further explored in therapeutic applications.


Polyhedron ◽  
2019 ◽  
Vol 166 ◽  
pp. 98-108 ◽  
Author(s):  
Chrisoula Kakoulidou ◽  
Stavros Kalogiannis ◽  
Panagiotis Angaridis ◽  
George Psomas

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