scholarly journals Determination of upper reference value of urinary calcium-creatinine ratio for the paediatric population in Burdwan district

2013 ◽  
Vol 03 (05) ◽  
pp. 455-459 ◽  
Author(s):  
Mrinal Pal ◽  
Subinay Datta ◽  
Amit Kumar Pradhan ◽  
Tapas Ghosh ◽  
Amrita Ganguly ◽  
...  
Keyword(s):  
Reference Value ◽  
Paediatric Population ◽  
Urinary Calcium ◽  
Creatinine Ratio

scholarly journals Normal Value of Random Urinary Calcium to Creatinine Ratio in Children in Zahedan, South-East of Iran

Health Scope ◽  
2020 ◽  
Vol 9 (4) ◽  
Author(s):  
Behzad Narouie ◽  
Simin Sadeghi Bojd ◽  
Mahdi Mohammadi
Keyword(s):  
Reference Values ◽  
Screening Method ◽  
Reference Value ◽  
Urinary Calcium ◽  
Primary School Children ◽  
Specific Reference ◽  
Creatinine Ratio ◽  
Cross Sectional ◽  
Significant Difference ◽  
East Of Iran

Background: Random urine calcium/creatinine ratio (UCa/Cr) is used practically for the screening of hypercalciuria. Objectives: This study aimed to determine the age-specific reference value of UCa/Cr and its relationship with urinary Na/K in children in Zahedan, South-East of Iran. Methods: In a cross-sectional study, UCa/Cr and UNa/K ratios were measured in non-fasting morning urine samples of 1,506 randomly selected primary school children. Results: The prevalence of hypercalciuria was 3.1%, with no significant difference between males and females. Mean UCa/Cr was 0.09 ± 0.21, and the 95th percentile was 0.27 and 0.22 in seven and 12-year-old children, respectively. Mean urinary UNa/UK was 2.90±1.89, and the 95th percentile was 7.83 and 10.57 in seven and 12-year-old children, respectively. The correlation between UCa/Cr and UNa/UK was statistically significant (r=0.128, P < 0.001). There was also a positive correlation between UCa/Cr and UNa/UK, especially in seven-year-old children (r=0.508, P < 0.001). Conclusions: Different reference values of UCa/Cr for seven and 12-years-old emphasize that age-specific reference values of UCa/Cr should be established for each population to be used as a screening method for hypercalciuria.

Determination of Traces Heavy Metals from Solid Residues Formed by Combustion of Lignite in Relation to Degree of Accessibility in Soil and Plants

2017 ◽  
Vol 68 (10) ◽  
pp. 2363-2366
Author(s):  
Delia Nica Badea
Keyword(s):  
Heavy Metals ◽  
Power Plant ◽  
Thermal Power ◽  
Reference Value ◽  
Combustion Products ◽  
Toxic Heavy Metals ◽  
Area Of Influence ◽  
Risk Potential

The paper evaluates the presence and content of traces of heavy metals Hg, Pb, Ni, Cd (total forms) from coal and solid combustion products, the degree of transfer and accessibility in the area of influence of a lignite power plant. The content of toxic heavy metals in residues are characterized by RE Meiji [ 1 (Pb and Hg) and REMeij �1 (Ni and Cd) for the filter ash. Pb and Ni content in the soil exceeds normal values, and Pb exceeds and alert value for sensitive soils around the residue deposit (70.20 mg.Kg-1). The degree of accessibility of the metals in plants (TF), reported at the Khan reference value (0.5), indicates a significant bioaccumulation level for the metals: Cd (1.9) and Hg (0.6) inside the deposit; Cd (0.39) at the base of the deposit, Hg (0.8) in the area of the thermal power plant. The trace levels of heavy metals analyzed by GFAAS and CVAAS (Hg), indicates a moderate risk potential for food safety and quality of life in the studied area.

scholarly journals Intermittent Bi-Daily Sub-cutaneous Teriparatide Administration in Children With Hypoparathyroidism: A Single-Center Experience

2021 ◽  
Vol 9 ◽  
Author(s):  
Julie Bernardor ◽  
Sacha Flammier ◽  
Sara Cabet ◽  
Sandrine Lemoine ◽  
Roland Chapurlat ◽  
...  
Keyword(s):  
Filtration Rate ◽  
Estimated Glomerular Filtration Rate ◽  
Urinary Calcium ◽  
Creatinine Ratio ◽  
Total Calcium ◽  
Single Center Experience ◽  
Symptomatic Hypocalcemia ◽  
75Th Quartile ◽  
Phosphate Control

Introduction: The use of teriparatide has been reported in children with hypoparathyroidism as an investigational physiologic replacement therapy.Methods: We aimed to retrospectively report our pediatric experience of bi-daily sub-cutaneous teriparatide. Results are presented as median (25th−75th quartile). As part of the routine follow-up of these patients with hypoparathyroidism, total calcium at H0 (i.e., just before injection) and H4 (i.e., 4 h after teriparatide injection) and other biomarker parameters were regularly assessed.Results: At a median age of 10.7 (8.1–12.6) years, an estimated glomerular filtration rate (eGFR) of 110 (95–118) mL/min/1.73 m2, calcium levels of 1.87 (1.81–1.96) mmol/L and an age-standardized phosphate of 3.8 (2.5–4.9) SDS, teriparatide therapy was introduced in 10 patients at the dose of 1.1 (0.7–1.5) μg/kg/day (20 μg twice daily), with further adjustment depending on calcium levels. Six patients already displayed nephrocalcinosis. Severe side effects were reported in one child: two episodes of symptomatic hypocalcemia and one of iatrogenic hypercalcemia; one teenager displayed dysgueusia. Calcium levels at H0 did not significantly increase whilst calcium at H4 and phosphate levels significantly increased and decreased, respectively. After 12 months, eGFR, calcium and age-standardized phosphate levels were 108 (90–122) mL/min/1.73 m2, 2.36 (2.23–2.48) mmol/L, 0.5 (−0.1 to 1.5), and 68 (63–74) nmol/L, respectively, with a significant decrease in phosphate levels (p = 0.01). Urinary calcium and calcium/creatinine ratio remained stable; no nephrolithiasis was observed but two moderate nephrocalcinosis appeared.Conclusion: Intermittent teriparatide therapy significantly improves calcium and phosphate control, without increasing calciuria. It appears to be safe and well-tolerated in children.

scholarly journals Total Fat Gravimetric Method Workflow in Portuguese Olives Using Closed-Vessel Microwave-Assisted Extraction (MAE)

Foods ◽  
2021 ◽  
Vol 10 (10) ◽  
pp. 2364
Author(s):  
João Gonçalo Lourenço ◽  
Daniel Ettlin ◽  
Inês Carrero Cardoso ◽  
Jesus M. Rodilla
Keyword(s):  
Limit Of Detection ◽  
Gravimetric Method ◽  
Reference Value ◽  
Microwave Assisted Extraction ◽  
Closed Vessel ◽  
Limit Of Quantification ◽  
Microwave Assisted ◽  
Assisted Extraction ◽  
Total Fat

A simple and rapid method for the quantitation of total fat in olive samples is designed, evaluated, and presented. This method is based on an innovative closed-vessel microwave-assisted extraction (MAE) technique. A method was designed for olives, and some figures of merits were evaluated: limit of detection (LOD), limit of quantification (LOQ) and expanded uncertainty (U). The data obtained in these experiences show that the workflow of the MAE method in a closed container is statistically equivalent to the other two methods, showing in this case better performance indicators (LOD = 0.02%, LOQ = 0.06%, and U = 15%). In addition, it is also demonstrated that the complete MAE method workflow allows the determination of total fat in a maximum of 12 analyses simultaneously for about 100 min in each run, which is the capacity of the rotor. This is a much better productivity when compared to the traditional Soxhlet-based method. Considering the sample workflow, the closed-vessel MAE method greatly simplifies sample handling, therefore minimizing sample loss during sample preparation and reducing analysis time. When MAE is compared to NIR-based methods, the advantage comes from there being no need for any type of calibration in the sample matrix. The MAE method itself can be used to determine the reference value for NIR calibration purposes. The results obtained for CRM using MAE were equivalent to the ones shown on the certificate.

scholarly journals Renal resistivity index as an aid in the diagnosis of acute kidney injury in bitches with pyometra

2021 ◽  
Vol 15 (3) ◽  
pp. 225-228
Author(s):  
Aline de Sousa Alves ◽  
Fernanda Vieira Henrique ◽  
Sabrina Barros Araújo ◽  
Dayanny de Sousa Alencar ◽  
Higina Moreira Melo ◽  
...  
Keyword(s):  
Acute Kidney Injury ◽  
Small Animal ◽  
Kidney Injury ◽  
Urinary Protein ◽  
Creatinine Ratio ◽  
Resistivity Index ◽  
Gamma Glutamyltransferase ◽  
Early Markers ◽  
The Right

This study aimed to evaluate the renal function of six bitches of various breeds and ages, with open pyometra, attended in the Small Animal Medical Clinic sector of the Veterinary Hospital from Federal University of Campina Grande, through the measurement of laboratory tests: urea and creatinine serum, dosage of the urinary Protein-Creatinine Ratio (PCR), urinary gamma-glutamyltransferase (GGT) and determination of the renal resistivity index (RI). The levels of urea and creatinine were elevated in 16.6% (1/6) of the female dogs; the urinary protein-creatinine ratio was increased in 66.6% (4/6), while the urinary gamma-glutamyltransferase value was elevated in 50% (3/6). The renal resistivity index was increased in the right and left kidneys by 66.6% (4/6) of bitches, with no statistical difference between them. It was concluded that the renal resistivity index was a practical and effective method to assist in the diagnosis of acute kidney injury, along with other early markers, such as PCR and urinary GGT.

scholarly journals Use of geotechnologies in mining planning in Quarries carbonated rocks - Contribution to the digital transition (Industry 4.0)

2021 ◽  
Vol 906 (1) ◽  
pp. 012015
Author(s):  
João Duarte ◽  
Francisco Sousa ◽  
Bruno Valente
Keyword(s):  
Industry 4.0 ◽  
Economic Valuation ◽  
Reference Value ◽  
Point Clouds ◽  
Detection Algorithm ◽  
Second Phase ◽  
Ornamental Stone ◽  
Use Of Resources ◽  
Photogrammetric Method

Abstract As part of the strategy for Industry 4.0, this work was developed to outline a methodology that is an important contribution to improve the efficiency and productivity of processes in the ornamental stone extraction industry. Since this sector is important for the Portuguese economy, it is imperative to optimize processes to improve their efficiency in the use of resources, economic valuation, and economic viability. Knowing that one of the main factors to take into account in the feasibility of an exploration of ornamental rocks is the density, persistence and attitude of the discontinuities present in the rock mass, a methodology is proposed that aims to map and characterize the existing discontinuities in the using the latest digital technologies and whenever possible open access (CloudCompare, Stereonet, 3D Block Expert). To this end, work was initially carried out on an active exploration front, identifying and characterizing, through the traditional method (compass and clinometer) and photogrammetry, existing discontinuities and statistically analysing their occurrence. The data analysis shows a variation in the attitude of the discontinuities in a range of -17.72 ° to 14.7 °, this variation corresponding to the strike. As a percentage, there is also a variation in the range of values, from -5.30% to 4.91%, with the reference value being the value obtained by the photogrammetric method. This step was also used to compare the acquired data and verify the variations between them depending on the method used. Photogrammetry was used with another complementary purpose, but very important for the proposed methodology, which is related to the 3D modelling of the fronts and the subsequent projection or extraction of the existing discontinuity plans. The determination of the attitude of the discontinuities was obtained through the manipulation of the point clouds obtained by the photogrammetric modelling, based on the technique of Structure for Motion [SfM] and application of the RANSAC Shape Detection algorithm of the CloudCompare® program, which allows the determination of the attitude of the discontinuities. The characterization of the discontinuities by the photogrammetric method provided the data that was used in the present study to calculate the blocometry in that sector. This was calculated using the 3D BlockExpert software, based on the exploration sequences. The program calculated the predicted volumes in each one, based on a standard dimension for the block of 2.7 × 3.0 × 2.0 meters. As a result, it was possible to compare a number of blocks the value predicted by the 449 modellings and the number of blocks produced 490. This difference of approximately 10% for this order of magnitude is acceptable and confirms the reliability of the proposed methodology. This evaluation using Geotechnologies allows data modelling to be effectively an important process in the planning of the extractive process, and with the development of this approach, it may introduce in a second phase the decision automation of the extractive process, based on economic and commercial criteria and last and third stage, the automation of the extractive process.

Hematuria and Hypercalciuria in Children With Diabetes Mellitus

PEDIATRICS ◽  
1987 ◽  
Vol 79 (5) ◽  
pp. 756-759
Author(s):  
John I. Malone ◽  
Saul Lowitt ◽  
John A. Duncan ◽  
Shirish C. Shah
Keyword(s):  
Diabetes Mellitus ◽  
Type I Diabetes ◽  
Large Population ◽  
Unknown Origin ◽  
Urinary Calcium ◽  
Calcium Excretion ◽  
Type I ◽  
Creatinine Ratio ◽  
Diabetic Children ◽  
Nondiabetic Control

Hematuria of unknown origin occurs in 30% of patients with diabetic nephropathy. In nondiabetic persons, hematuria may be caused by hypercalciuria with or without nephrolithiasis. Eight children with type I diabetes mellitus, hematuria, and hypercalciuria were observed in our clinic during a 1-year period. Two of these also had evidence of renal papillary necrosis. To assess the importance of hypercalciuria in the pathogenesis of hematuria in children with diabetes mellitus, we measured urinary calcium excretion in a large population of such patients. The calcium to creatinine ratio in the urine of diabetic children (0.21 ± 0.01) was greater than that of nondiabetic children (0.12 ± 0.01). A calcium to creatinine ratio of 0.28 was established as the upper limit of normal in our nondiabetic population, and 27% of the diabetic children were hypercalciuric on this basis. The diabetic children with hypercalciuria also had hyperphosphaturia and a urinary CaHPO4.2H2O molar ion product three times that found in the nondiabetic control population. These data suggest that many children with diabetes are at risk for renal damage due to hypercalciuria. Because hypercalciuria is more common in diabetic than nondiabetic children, it may play a previously unrecognized role in the renal disease associated with diabetes mellitus.

Albumin excretion rate, albumin concentration, and albumin/creatinine ratio compared for screening diabetics for slight albuminuria.

1988 ◽  
Vol 34 (10) ◽  
pp. 2019-2021 ◽  
Author(s):  
A S Hutchison ◽  
D S O'Reilly ◽  
A C MacCuish
Keyword(s):  
Predictive Value ◽  
Excretion Rate ◽  
Albumin Excretion Rate ◽  
Albumin Concentration ◽  
Creatinine Ratio ◽  
Initial Screening ◽  
Negative Sample ◽  
Albumin Creatinine Ratio ◽  
Albumin Excretion

Abstract Slight albuminuria, an overnight albumin excretion rate (AER) greater than 30 micrograms/min in an "Albustix"-negative sample, predicts development of diabetic nephropathy. This study compares the AERs for 261 timed overnight urine collections with the albumin concentrations and albumin/creatinine ratios for the same specimens (equivalent to first morning specimens). Thirty-one specimens (11.9%) had AERs greater than 30 micrograms/min. Use of an albumin/creatinine ratio greater than 3.0 mg/mmol to predict an AER greater than 30 micrograms/min gave a sensitivity of 96.8%, a specificity of 93.9%, and a predictive value of 68.2%, with a correlation coefficient of 0.921. Use of an albumin concentration greater than 17 mg/L gave a sensitivity of 96.8%, a specificity of 90.9%, a predictive value of 58.8%, and a slightly poorer correlation (r = 0.904). Evidently either method is acceptable as an initial screening procedure, but determination of albumin concentration alone would be preferable because of lesser cost.

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