scholarly journals Conditional Mutations in Drosophila: Concept of Genes That Control Individual Development

2018 ◽  
Vol 09 (06) ◽  
pp. 243-272
Author(s):  
Boris F. Chadov ◽  
Eugenia V. Chadova ◽  
Nina B. Fedorova
2011 ◽  
Vol 23 (1) ◽  
pp. 204
Author(s):  
I. G. F. Goovaerts ◽  
J. L. M. R. Leroy ◽  
E. Merckx ◽  
S. Andries ◽  
P. E. J. Bols

The ability to produce embryos singly in vitro (in vitro production, IVP) would be a useful tool for many purposes. Without the interfering effects of other developing or degenerating oocytes or embryos, such an individual IVP system is the tool of choice for studies on oocyte quality and oocyte–embryo metabolism. Unfortunately, individual IVP in most cases leads to unsatisfactorily low blastocyst rates. Earlier work showed that individual culture of zygotes on a cumulus cell (CC) monolayer resulted in comparable numbers of good-quality embryos, as obtained following regular group culture (Goovaerts et al. 2009 Theriogenology 71, 729–738). However, co-culture with somatic cells is often criticised because of the undefined culture conditions and for sanitary reasons. In the cited study, CC for monolayer production were obtained from a different batch of ovaries. Our specific aim was to use CC from the zygote itself (autologous CC). Grade I COC (n = 660) were collected from slaughterhouse ovaries and randomly assigned to 2 treatments (5 replicates): a completely individual ‘single-oocyte’ IVP protocol, or routine group IVP as a control. Individual maturation (TCM-199 + 20% serum) and fertilization were performed in 20-μL droplets under oil in 24-well plates. Subsequently, each zygote was stripped and cultured in 20 μL of medium (SOF + 5% serum, 90% N2, 5% CO2, 5% O2), to which the autologous stripped CC were added. Group maturation and fertilization were carried out per 100 COC in 500 μL, whereas group culture was performed per 25 zygotes in 50-μL droplets under oil. Cleavage, blastocyst, and hatching rates were determined 2, 8, and 10 days post-fertilization, respectively. Possible effects of the individual and group cultures were evaluated with binary logistic regression (SPSS 15.0, SPSS Inc., Chicago, IL). No interactions between replicate and treatment were found (P > 0.05). Although a blastocyst rate of 15.1% was obtained using single IVP, the general efficacy of the single-embryo production system was lower when compared with group culture (Table 1). In conclusion, although developmental competence was impaired using individual IVP, co-culture with autologous cumulus cells can be useful in specific experimental setups in which the influence of other oocytes or embryos or heterologous somatic cells is unacceptable. Table 1.Cleavage, blastocyst, and hatching rates after individual and group in vitro production (IVP)


Author(s):  
Suhardi Suhardi

Mental revolution of education requires efforts to print educated human beings by having the motivation to meet the standards of achievement excellence, such as ethos of progress, ethics, achievement motivation, discipline, optimistic, productive, innovative and active views. This can be implemented with character education. Character education is one of the soft skill tools that can be integrated in learning in each subject. Learning activities using an active learning approach have a strategic role in instilling national character values so that students are able to behave and act on values that have become their personality. The purpose of this study was to find and analyze about: 1) Implementation of Character Education to Build Adiwiyata-Based Mental Revolution and Multiculturalism; 2) Implementation of Character Education to Build Mental Revolution in Organizational Culture. This study uses a qualitative approach with phenomenological naturatistics (phenomenology approach), with a descriptive type of case study research design. Data were analyzed using data analysis techniques: data reduction, data analysis and conclusions. The results of the study are: The application of character education to develop a mental revolution can be started from the character of building the environment. Environmental character is very important for individual development. The implementation of character education in building a mental revolution can emphasize the internalization of multicultural values and Adiwiyata which in the end will form a loving environmental awareness and foster a spirit of tolerance.


Author(s):  
Jean-Pierre Amigues

The article presents a holistic view on neuroosteopathy. It demonstrates the connection between the congenital and the acquired alterations with due regard to the epigenetic aspects of morphogenesis in different periods of the organism’s individual development. On the basis of the analysis of scientific literature and of the clinical osteopathic experience the connection between the child’s motor development and the formation of his nervous system is shown. The article presents a plan of osteopathic treatment of the lesions diagnosed which is based on the analysis of the connection between the motor acts, gestures, positions and congenital reflexes.


2020 ◽  
Vol 1 (1) ◽  
pp. 27-35
Author(s):  
Sovanbrata Talukdar

This research emerges with internal financial constraint. How financial constraint may lead to economic recess or back. This financial constraint is different than external finance constraint, and is not due to lack of gold, etc. It explains the positive relationship between excess return in stock market (ERSM) and non-real funding or riskier credit. The matter comes under imperfect market banking. It includes subsequently banking behavior and failure of central bank policy to control individual banks under these circumstances. In addition, it presents measures to get awareness before default comes, as financial default rare and crisis in financial market comes much before that.


Author(s):  
Misa Kayama ◽  
Wendy Haight ◽  
May-Lee Ku ◽  
Minhae Cho ◽  
Hee Yun Lee

Stigmatization is part of the everyday lives of children with disabilities, their families, and their friends. Negative social encounters, even with perfect strangers, can dampen joyful occasions, add stress to challenging situations, and lead to social isolation. This book describes a program of research spanning a decade that seeks to understand disabilities in their developmental and cultural contexts. The authors are especially interested in understanding adults’ socialization practices that promise to reduce stigmatization in the next generation. Guided by developmental cultural psychology, including the concept of “universalism without uniformity,” the authors focus on the understandings and responses to disability and associated stigmatization of elementary-school educators practicing in Japan, South Korea, Taiwan, and the U.S. Educators from all four cultural groups expressed strikingly similar concerns about the impact of stigmatization on the emerging cultural self, both of children with disabilities and their typically developing peers. Educators also described culturally nuanced socialization goals and practices pertaining to inclusive education. In Japan, for instance, educators emphasized the importance of peer group belonging and strategies to support the participation of children with disabilities. In the U.S., educators placed relatively more emphasis on individual development and discussed strategies for the equitable treatment of children with disabilities. Educators in South Korea and Taiwan emphasized the cultivation of compassion in typically developing children. The understanding gained through examination of how diverse individuals address common challenges using cultural resources available in their everyday lives provides important lessons for strengthening theory, policy, and programs.


2021 ◽  
pp. 014662162110131
Author(s):  
Leah Feuerstahler ◽  
Mark Wilson

In between-item multidimensional item response models, it is often desirable to compare individual latent trait estimates across dimensions. These comparisons are only justified if the model dimensions are scaled relative to each other. Traditionally, this scaling is done using approaches such as standardization—fixing the latent mean and standard deviation to 0 and 1 for all dimensions. However, approaches such as standardization do not guarantee that Rasch model properties hold across dimensions. Specifically, for between-item multidimensional Rasch family models, the unique ordering of items holds within dimensions, but not across dimensions. Previously, Feuerstahler and Wilson described the concept of scale alignment, which aims to enforce the unique ordering of items across dimensions by linearly transforming item parameters within dimensions. In this article, we extend the concept of scale alignment to the between-item multidimensional partial credit model and to models fit using incomplete data. We illustrate this method in the context of the Kindergarten Individual Development Survey (KIDS), a multidimensional survey of kindergarten readiness used in the state of Illinois. We also present simulation results that demonstrate the effectiveness of scale alignment in the context of polytomous item response models and missing data.


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