scholarly journals Effects of vacuum-assisted closure and Drotrecogin alpha on inflammatory markers in severe acute pancreatitis

2013 ◽  
Vol 04 (08) ◽  
pp. 43-53
Author(s):  
Oscar Arias-Carvajal ◽  
José Manuel Hermosillo-Sandoval ◽  
Carlos Alberto Gutiérrez-Martínez ◽  
Fermín Paul Pacheco-Moisés ◽  
Genaro Gabriel Ortiz ◽  
...  
Keyword(s):  
Acute Pancreatitis ◽  
Severe Acute Pancreatitis ◽  
Inflammatory Markers ◽  
Vacuum Assisted Closure ◽  
Drotrecogin Alpha

scholarly journals 566 A Study to Investigate CRP and WBC As Early Prognostic Tools in Severe Pancreatitis

2021 ◽  
Vol 108 (Supplement_6) ◽  
Author(s):  
Y Rajjoub ◽  
M Zourob ◽  
S Khan
Keyword(s):  
Acute Pancreatitis ◽  
Retrospective Study ◽  
Severe Acute Pancreatitis ◽  
Inflammatory Markers ◽  
Prognostic Value ◽  
Roc Curves ◽  
Patient Demographics ◽  
A Value ◽  
Severe Pancreatitis ◽  
Mild Acute Pancreatitis

Abstract Aim To establish the prognostic value of raised inflammatory markers on Day 3 in patients with severe acute pancreatitis Method A retrospective study between 01/02/18 till 31/01/19 including all patients with acute pancreatitis. Patient demographics, the aetiology, treatment, severity (as per modified Atlanta's criteria) and inflammatory markers on Day 3 of the hospital admission were included. ROC curves were subsequently generated. Results 127 patients were included with a median age of 59 years. 113 patients were diagnosed with mild acute pancreatitis while 14 patients had severe acute pancreatitis. The ROC curve illustrates that the value of CRP which maximises discrimination was 176 mg, with a sensitivity of 83% and specificity of 76%. For WBC with a value of 12.11 showed 100% sensitivity and 80% specificity. Conclusions This study highlights that elevated CRP and WBC on Day 3 could both be good predictive tools for patients who develop severe pancreatitis.

Effect of Enteral Versus Parenteral Nutrition on Inflammatory Markers in Severe Acute Pancreatitis

Pancreas ◽  
2007 ◽  
Vol 35 (3) ◽  
pp. 292 ◽  
Author(s):  
Josefina Mora ◽  
Meritxell Casas ◽  
Daniel Cardona ◽  
Antoni Farré
Keyword(s):  
Acute Pancreatitis ◽  
Parenteral Nutrition ◽  
Severe Acute Pancreatitis ◽  
Inflammatory Markers

Gut permeabillity and nitric oxide: Evidence for an endotoxin mediated inflammatory response in severe acute pancreatitis

2001 ◽  
Vol 120 (5) ◽  
pp. A468-A469
Author(s):  
S RAHMAN ◽  
B AMMORI ◽  
I MARTIN ◽  
G BARCLAY ◽  
M LARVIN ◽  
...  
Keyword(s):  
Nitric Oxide ◽  
Acute Pancreatitis ◽  
Inflammatory Response ◽  
Severe Acute Pancreatitis

Clinical Profile and Outcomes in Patients with Acute Pancreatitis attending a Teaching Hospital at Gandaki Province, Nepal

2020 ◽  
Vol 16 (3) ◽  
Author(s):  
Subash Bhattarai ◽  
Merina Gyawali
Keyword(s):  
Acute Pancreatitis ◽  
Severe Acute Pancreatitis ◽  
Age Groups ◽  
Data Entry ◽  
Kidney Injury ◽  
Severity Index ◽  
Clinical Profile ◽  
Cross Sectional ◽  
Systemic Complications ◽  
Keywords Alcohol

Background: Acute pancreatitis (AP) is inflammatory process of pancreas presenting with acute abdominal pain.The majority of patients have mild disease. Some patients develop local and systemic complications with increased morbidity and mortality. This study was undertaken to describe the clinical profile and outcomes in patients with acute pancreatitis.   Methods:  A cross-sectional hospital based study comprising of 62 consecutive patients with acute pancreatitis were enrolled between Jan 2019 to August 2020. Clinical profile at admission, complications and clinical outcomes including mortality were studied. Patients were classified into mild, moderately severe and severe acute pancreatitis based on revised Atlanta classification and modified CT severity index.  Data entry was done in Statistical Packages for the Social Sciences version 20. Results: The mean age of study subjects was 44±10.87 years with 43 (56%) males and 19 (44%) females (M:F=2.1:1). The commonest etiology of pancreatitis was alcohol (53.2%) followed by biliary pancreatitis (37.1%)  The most common presentation was abdominal pain (100%). The most common complication was pancreatic necrosis (21%) followed by acute kidney injury (19.4%) and pleural effusion (17.3%). Majority( 72.6%) was mild and 17.7% had severe acute pancreatitis. Mortality was seen in 6.5% patients. Mortality was observed in patients with persistent complications, organ failure, low serum calcium and high modified CT severity index.   Conclusions: Alcohol and gallstones were the two main etiologies of acute pancreatitis and were common in males, and in middle age groups. Majority presented with mild severity. Mortality was observed in some patients with severe acute pancreatitis.   Keywords: alcohol; biliary; CT severity index; mortality; outcome; pancreatitis          

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