Heart Failure Models: Traditional and Novel Therapy

2015 ◽  
Vol 13 (5) ◽  
pp. 658-669 ◽  
Author(s):  
Mohamed Haidara ◽  
Abdullah Assiri ◽  
Hanaa Yassin ◽  
Hania Ammar ◽  
Milan Obradovic ◽  
...  
Keyword(s):  
Heart Failure ◽  
Novel Therapy ◽  
Failure Models

scholarly journals Application of genetic programming to modeling pipe failures in water distribution systems

2010 ◽  
Vol 13 (3) ◽  
pp. 419-428 ◽  
Author(s):  
Qiang Xu ◽  
Qiuwen Chen ◽  
Weifeng Li
Keyword(s):  
Genetic Programming ◽  
Distribution System ◽  
Distribution Systems ◽  
Water Distribution ◽  
Pipe Failure ◽  
Beijing City ◽  
Failure Data ◽  
Processing Strategies ◽  
Gis Data ◽  
Failure Models

The water loss from a water distribution system is a serious problem for many cities, which incurs enormous economic and social loss. However, the economic and human resource costs to exactly locate the leakage are extraordinarily high. Thus, reliable and robust pipe failure models are demanded to assess a pipe's propensity to fail. Beijing City was selected as the case study area and the pipe failure data for 19 years (1987–2005) were analyzed. Three different kinds of methods were applied to build pipe failure models. First, a statistical model was built, which discovered that the ages of leakage pipes followed the Weibull distribution. Then, two other models were developed using genetic programming (GP) with different data pre-processing strategies. The three models were compared thereafter and the best model was applied to assess the criticality of all the pipe segments of the entire water supply network in Beijing City based on GIS data.

scholarly journals Role of Dietary Nutritional Treatment on Hepatic and Intestinal Damage in Transplantation with Steatotic and Non-Steatotic Liver Grafts from Brain Dead Donors

Nutrients ◽  
2021 ◽  
Vol 13 (8) ◽  
pp. 2554
Author(s):  
Marc Micó-Carnero ◽  
Araní Casillas-Ramírez ◽  
Albert Caballeria-Casals ◽  
Carlos Rojano-Alfonso ◽  
Alfredo Sánchez-González ◽  
...  
Keyword(s):  
Growth Factor ◽  
Gut Microbiota ◽  
Intestinal Inflammation ◽  
Mucosal Damage ◽  
Hepatic Damage ◽  
Intestinal Damage ◽  
Edema Formation ◽  
Steatotic Liver ◽  
Damage And Failure

Herein, we investigate whether: (1) the administration of glucose or a lipid emulsion is useful in liver transplantation (LT) using steatotic (induced genetically or nutritionally) or non-steatotic livers from donors after brain death (DBDs); and (2) any such benefits are due to reductions in intestinal damage and consequently to gut microbiota preservation. In recipients from DBDs, we show increased hepatic damage and failure in the maintenance of ATP, glycogen, phospholipid and growth factor (HGF, IGF1 and VEGFA) levels, compared to recipients from non-DBDs. In recipients of non-steatotic grafts from DBDs, the administration of glucose or lipids did not protect against hepatic damage. This was associated with unchanged ATP, glycogen, phospholipid and growth factor levels. However, the administration of lipids in steatotic grafts from DBDs protected against damage and ATP and glycogen drop and increased phospholipid levels. This was associated with increases in growth factors. In all recipients from DBDs, intestinal inflammation and damage (evaluated by LPS, vascular permeability, mucosal damage, TLR4, TNF, IL1, IL-10, MPO, MDA and edema formation) was not shown. In such cases, potential changes in gut microbiota would not be relevant since neither inflammation nor damage was evidenced in the intestine following LT in any of the groups evaluated. In conclusion, lipid treatment is the preferable nutritional support to protect against hepatic damage in steatotic LT from DBDs; the benefits were independent of alterations in the recipient intestine.

Damage and failure analyses of 3D4d braided composite shafts under torsional load and the effects of braid processing parameters on their torsional properties

2021 ◽  
Vol 42 (4) ◽  
pp. 1912-1944
Author(s):  
Ya Wang ◽  
Zhen‐Guo Liu ◽  
Yun‐Peng Yi ◽  
Yu‐Chen Wei ◽  
Zhi‐jian Li ◽  
...  
Keyword(s):  
Processing Parameters ◽  
Braided Composite ◽  
Damage And Failure ◽  
Torsional Load ◽  
Torsional Properties
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