scholarly journals Exposure to Airborne Particulate Matter: An Additional Risk Factor for Metabolic Syndrome in Saudi Arabia

Author(s):  
Mansour A. Alghamdi Mansour A. Alghamdi

. Metabolic syndrome is a serious problem in Saudi Arabia. It has been attributed mainly to life style. Exposure to airborne particulate matter is a subject of concern in Jeddah. The present study aimed to find a possible association of metabolic syndrome prevalence with levels of particulate matter and their elemental constituents. The study was conducted in two districts of Jeddah, Al Nuzlah and Al Rehab. PM10 and PM2.5 were measured in each district as well as their elemental composition. Metabolic syndrome was defined by the presence of three components: hyperglycemia, hypertension and obesity. Al Nuzlah district showed higher prevalence of metabolic syndrome, together with higher levels of PM2.5, nickel and cadmium. It can be concluded that exposure to particulate matter may be considered as an additional risk factor for metabolic syndrome.

1997 ◽  
Vol 31 (8) ◽  
pp. 1185-1193 ◽  
Author(s):  
Nicole A.H. Janssen ◽  
Dimphe F.M. Van Mansom ◽  
Katinka Van Der Jagt ◽  
Hendrik Harssema ◽  
Gerard Hoek

2021 ◽  
Vol 129 (Suppl_1) ◽  
Author(s):  
Devin R O'Piela ◽  
Ty A Saldana ◽  
David M Aslaner ◽  
Matthew W Gorr ◽  
Amy R Mackos ◽  
...  

Air pollution has detrimental effects on cardiovascular and lung function, and the extent of its pathological consequences continues to be uncovered. Recently, air pollution has been implicated in the development of Alzheimer Disease (AD) progression. AD and heart failure are common co-morbidities, giving reason to believe that cardiovascular dysfunction may contribute to AD. A known contributor to cardiovascular dysfunction-particulate matter (PM 2.5 , < 2.5 μm diameter)—is a critical component of air pollution and is considered a risk factor for heart failure and AD development. This co-morbidity pattern and shared environmental risk factor prompted the hypothesis that PM 2.5 contributes to cardiovascular dysfunction in a transgenic mouse model of AD. We tested our hypothesis by subjecting 6-month-old transgenic (APP) and non-carrier wildtype (WT) male mice to filtered air (FA) or PM 2.5 for 5 days/week, 6 hours/day for 3 months (n = 34). Following exposure, echocardiography, pressure-volume (PV) loops, and respiratory mechanics were performed to detect cardiac and pulmonary changes associated with genotype and exposure conditions among the 3-month group. Echocardiography revealed left ventricular anterior wall thickness in systole was significantly elevated among PM-exposed APP mice compared to FA-exposed APP controls. PV data demonstrated significant reduced end-systolic elastance in PM-exposed mice compared to FA-exposed mice in both WT and APP mouse models, demonstrating impaired contractility. PV loops also showed that the time constant of isovolumetric relaxation was increased in PM-exposed compared to FA-exposed WT mice. APP mice experienced higher lung resistance and central airway resistance with an increasing dose of methacholine. Taken together, these findings indicate airborne particulate matter exposure causes cardiac and pulmonary dysfunction in a transgenic mouse model of AD.


2017 ◽  
Vol 590-591 ◽  
pp. 531-539 ◽  
Author(s):  
Roy M. Harrison ◽  
Dimitrios Bousiotis ◽  
A.M. Mohorjy ◽  
A.K. Alkhalaf ◽  
M. Shamy ◽  
...  

2001 ◽  
Vol 11 (01n02) ◽  
pp. 61-67 ◽  
Author(s):  
J. FLORES M. ◽  
F. ALDAPE

The contribution to the atmospheric pollution in Mexico City's conurbation that comes from the northern area has been considered significant for a long time. Therefore, it is important to determine its elemental composition as well as their correlation in sites along the suspected trajectories of airborne particulate matter. Samples were collected simultaneously in two sampling sites along the prevailing wind trajectory in northern Mexico City, and its elemental composition were determined by PIXE. The Sample collection was performed daily from 17 February 14 March 1997 in Xalostoc, an industrial zone in the State of Mexico, and Ticomán within Mexico City. Two samples a day were taken in two periods: 7-19 h and 19-7 h. The samplers used separated particles into two particle size fractions fractions, PM25 and PM15. Three main correlation group of elemental concentrations were determined: fuel combustion, earth crust and industrial origin. The sampling site within Mexico City, Ticomán, was found with an overall tendency of higher elemental concentrations, showing not only influence of local pollution sources, but also that of wind transported particles from neighboring industrial zones such as Xalostoc.


1990 ◽  
Vol 91 ◽  
pp. 251-267 ◽  
Author(s):  
C.M. Rojas ◽  
L. Figueroa ◽  
K.H. Janssens ◽  
P.E. Van Espen ◽  
F.C. Adams ◽  
...  

Sign in / Sign up

Export Citation Format

Share Document