scholarly journals Vaginal Colonization by Escherichia coli in Pregnant Women at King Abdulaziz University Hospital, Jeddah, Saudi Arabia

2017 ◽  
Vol 24 (3) ◽  
pp. 39-49
Author(s):  
Taghreed J. Jamal ◽  
Hassan El-Banna A. Younus ◽  
Hassan S. Abduljabbar ◽  
Asif A. Jiman-Fatani ◽  
Amal F. Makled
Keyword(s):  
Escherichia Coli ◽  
Saudi Arabia ◽  
Pregnant Women ◽  
Antimicrobial Agents ◽  
University Hospital ◽  
Vaginal Colonization ◽  
Antimicrobial Susceptibility Tests ◽  
Automated Technology ◽  
King Abdulaziz University ◽  
Susceptibility Tests

Maternal and neonatal infections by Escherichia coli remain a challenging problem for obstetricians and pediatricians. This study aims to determine the prevalence of vaginal colonization by Escherichia coli among pregnant women attending the Antenatal Clinics at King Abdulaziz University Hospital in Jeddah- Saudi Arabia, and to investigate the susceptibility of isolated Escherichia coli to the most commonly used antimicrobials. In this study, 100 pregnant women in the last trimester and 25 non-pregnant women were screened for vaginal colonization of Escherichia coli. The suspected colonies were identified by conventional methods and were confirmed by automated technology "Vitek 2 System". Also, antimicrobial susceptibility tests were done by the same methods". Escherichia coli isolates were serotyped to detect the presence of K1 antigen. Out of 100 pregnant women in the last trimester; twenty-one (21%) were Escherichia coli positive. Also, out of 25 non-pregnant women; four (16%) were Escherichia coli-positive. All of the isolated Escherichia coli were susceptible to most antimicrobial agents. The percentage of vaginal Escherichia coli resistance to trimethoprim/sulfamethoxazole, ampicillin and piperacillin ranged from 38.1% to 42.9%. The virulence factor K1 antigen was demonstrated in 42.9% of Escherichia coli -positive pregnant women.

scholarly journals Anti-toxoplasma Antibody Prevalence and Cost-effectiveness in Pregnant Women at the King Abdulaziz University Hospital, Jeddah, Saudi Arabia

Cureus ◽  
2020 ◽  
Author(s):  
Ashwag H Mohajab ◽  
Hisham Z Alshehri ◽  
Riyadh O Shati ◽  
Ahmed A Alshehri ◽  
Mohammed A Alafghani ◽  
...  
Keyword(s):  
Saudi Arabia ◽  
Cost Effectiveness ◽  
Pregnant Women ◽  
University Hospital ◽  
Antibody Prevalence ◽  
King Abdulaziz University

scholarly journals Asymptomatic Bacteriuria in Pregnant Women in Jeddah, Western Region of Saudi Arabia: Call for Assessment

2010 ◽  
Vol 17 (1) ◽  
pp. 29-42 ◽  
Author(s):  
Sharifa A. Al Sibiani
Keyword(s):  
Saudi Arabia ◽  
Pregnant Women ◽  
Asymptomatic Bacteriuria ◽  
Clinic Visit ◽  
University Hospital ◽  
National Scale ◽  
Lack Of Information ◽  
King Abdulaziz University ◽  
Nation Wide Survey ◽  
Low Prevalence

To determine the prevalence and the causative organisms of asymptomatic bacteriuria among pregnant women attending their first prenatal visit at King Abdulaziz University Hospital and in a private clinic at Dr. Erfan and Bagedo Hospital, Jeddah, Saudi Arabia. A retrospective analysis was performed of the routine prenatal screening (urine culture tests) of 9,698 women attending their first prenatal clinic visit between 1 January 2004 to 31 December 2007. They were reviewed, analyzed, and correlated with data on patients’ age, nationality, gravidity, and number of previous abortions. Of 9,698 women, only 166 (1.7%) showed significant bacterial growth, and 1,918 patients (19.8%) were reported as heavy mixed growth. The most common bacterium isolated was Escherichia coli on 88 patients (53%). In this study, low prevalence of bacteriuria among pregnant women was compared to the only two available published studies conducted in the 80's in Saudi Arabia. In view of the lack of information regarding asymptomatic bacteriuria in pregnancy, and the findings of this study, the importance of a conducting a nation-wide survey to guide the revision of practice on a national scale in Saudi Arabia has increased.

scholarly journals Patterns of infections and antimicrobial drugs’ prescribing among pregnant women in Saudi Arabia: a cross sectional study

2021 ◽  
Vol 14 (1) ◽  
Author(s):  
Mohamed A. Baraka ◽  
Lina Hussain AlLehaibi ◽  
Hind Nasser AlSuwaidan ◽  
Duaa Alsulaiman ◽  
Md. Ashraful Islam ◽  
...  
Keyword(s):  
Saudi Arabia ◽  
Pregnant Women ◽  
Antimicrobial Agents ◽  
Cross Sectional Study ◽  
Maternal Complications ◽  
Multicenter Studies ◽  
Antimicrobial Drugs ◽  
Cross Sectional ◽  
Categorization System ◽  
Tract Infections

Abstract Background Antimicrobial agents are among the most commonly prescribed drugs in pregnancy due to the increased susceptibility to infections during pregnancy. Antimicrobials can contribute to different maternal complications. Therefore, it is important to study their patterns in prescription and utilization. The data regarding this issue is scarce in Saudi Arabia. Therefore, the aim of this study is to generate data on the antimicrobial agents that are most commonly prescribed during pregnancy as well as their indications and safety. Methods This is a retrospective study focusing on pregnant women with a known antimicrobial use at Johns Hopkins Aramco Healthcare (JHAH). The sample included 344 pregnant women with a total of 688 antimicrobial agents prescribed. Data was collected on the proportion of pregnant women who received antimicrobial agents and on the drug safety during pregnancy using the risk categorization system of the U.S. Food and Drug Administration (FDA). Results The results showed that urinary tract infections (UTIs) were the most reported (59%) infectious diseases. Around 48% of pregnant women received antimicrobial medications at some point during pregnancy. The top two antimicrobial agents based on prescription frequency were B-lactams (44.6%) and azole anti-fungals (30%). The prescribed drugs in the study were found to be from classes B, C and D under the FDA risk classification system. Conclusion The study revealed a high proportion of antimicrobials prescribed during pregnancy that might pose risks to mothers and their fetuses. Future multicenter studies are warranted to evaluate the rational prescription of antimicrobial medications during pregnancy.

Effectiveness of ZnO Nano Particles against the Foodborne Microbial Pathogens E. coli and S. aureus

2020 ◽  
Vol 15 (2) ◽  
pp. 87-94
Keyword(s):  
Antimicrobial Agents ◽  
Inhibitory Concentration ◽  
Antimicrobial Effect ◽  
Nano Particles ◽  
Microbial Pathogens ◽  
Gram Positive ◽  
Gram Negative ◽  
E Coli ◽  
Antimicrobial Susceptibility Tests ◽  
Susceptibility Tests

In this work, various concentrations of ZnO nano particles, prepared by the coprecipitation method with a size range of 47-68 nm, have been investigated as antimicrobial agents. Dilution antimicrobial susceptibility tests were carried out on two kinds of microbes (Gram-positive Staphylococcus aureus and Gram-negative Escherichia coli) according to the standard method recommended by Clinical and Laboratory Standards Institute, CLSI-2015-M07-A10. The results showed that the antimicrobial effect is larger, the higher the concentration of ZnO nano particles in solution. It was also found that Gram-positive microbes are more sensitive to ZnO nano particles when compared with the Gram-negative ones. The minimum inhibitory concentration (MIC) for E. coli was found to be 50 mg/mL while that for S. aureus was 25 mg/mL. The minimum bactericidal concentration (MBC) was 1600 mg/mL for E. coli and 800 mg/mL for S. aureus.

Effect of laparoscopic sleeve gastrectomy on metabolic and nutritional changes at King Abdulaziz University Hospital, Saudi Arabia

2018 ◽  
Vol 6 (1) ◽  
pp. 25
Author(s):  
WisamH Jamal ◽  
Rawan Alsolami ◽  
YaraA Fayoumi ◽  
SarahA Almaghrabi ◽  
MuradM Aljiffry ◽  
...  
Keyword(s):  
Saudi Arabia ◽  
Sleeve Gastrectomy ◽  
Laparoscopic Sleeve Gastrectomy ◽  
University Hospital ◽  
King Abdulaziz University ◽  
Nutritional Changes

scholarly journals Antimicrobial Resistance Profile of Different Clinical Isolates against Third-Generation Cephalosporins

2018 ◽  
Vol 2018 ◽  
pp. 1-7 ◽  
Author(s):  
Fanta Gashe ◽  
Eshetu Mulisa ◽  
Mekidim Mekonnen ◽  
Gemechu Zeleke
Keyword(s):  
Escherichia Coli ◽  
Staphylococcus Aureus ◽  
Antimicrobial Resistance ◽  
Antimicrobial Susceptibility ◽  
Generation Cephalosporin ◽  
Third Generation ◽  
Bacterial Isolates ◽  
Antimicrobial Susceptibility Tests ◽  
Susceptibility Tests ◽  
Jimma University

Background. Drug resistant microorganisms lead to an increase in morbidity and mortality as they boost the risk of inappropriate therapy. Hence, data on antimicrobial resistance help define the best possible treatment for individual patients. Therefore, this study aimed to screen the antimicrobial resistant profile of 3rd generation cephalosporin drugs in Jimma University Specialized Teaching Hospital. Methods. A hospital based prospective cross-sectional study was conducted in Jimma University Specialized Hospital (JUSH) from April to August 2016. The clinical samples such as wound swab, urine, sputum, and stool were collected from hospitalized patients. Then, bacterial species were isolated and identified as per the standard microbiological methods. Antimicrobial susceptibility tests were carried out using various antimicrobial discs by Kirby–Bauer disc diffusion method. Results. Totally, 248 bacterial isolates were obtained from 154 (62.1%) male and 94 (37.9%) female patients. Escherichia coli (25.4%) and Staphylococcus aureus (19.0 %) were the predominant organisms isolated from specimens. About 140 (56.5%) and 149 (60.1%) of the total bacterial isolates were found to be resistant to ceftriaxone and ceftazidime, respectively. The majority of Escherichia coli isolates 46 (73%) were resistant to ceftriaxone and 41 (65%) of them were resistant to ceftazidime. Staphylococcus aureus, which accounted 19% of the total bacterial isolates, showed 23.4% and 34% resistance to ceftriaxone and ceftazidime, respectively. Among the bacterial strains revealing resistant to ceftriazone and ceftazidime, about 109 (44%) and 108 (43.5%) of them were resistant to two, three, or four other drugs, respectively. Conclusion. Bacterial resistance towards third-generation cephalosporin (ceftriaxone and ceftazidime) is escalating as more than half of the isolated strains demonstrated resistance to these drugs. Moreover, these strains also revealed multidrug resistance mainly against clinically used drugs which could render therapy unsuccessful. Therefore, in clinical use appropriate medications should be selected based on the data obtained from antimicrobial susceptibility tests.

Sign in / Sign up

Export Citation Format

Share Document