scholarly journals Topical nasal decongestant oxymetazoline (0.05%) provides relief of nasal symptoms for 12 hours

2018 ◽  
Vol 0 (0) ◽  
Author(s):  
H.M. Druce ◽  
D.L. Ramsey ◽  
S. Karnati ◽  
A.N. Carr
Keyword(s):  
Nasal Decongestant ◽  
Nasal Symptoms

Nasal Symptoms of Mucoviscidosis

1970 ◽  
Vol 3 (2) ◽  
pp. 257-264
Author(s):  
Daniel C. Baker ◽  
J. Thomas Smith
Keyword(s):  
Nasal Symptoms

scholarly journals Cold bubble humidification of low-flow oxygen does not prevent acute changes in inflammation and oxidative stress at nasal mucosa

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Lauriana Alves Santana ◽  
Suellen Karoline Moreira Bezerra ◽  
Beatriz Mangueira Saraiva-Romanholo ◽  
Wellington Pereira Yamaguti ◽  
Iolanda de Fátima Lopes Calvo Tibério ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Nasal Mucosa ◽  
Oxygen Therapy ◽  
Mucociliary Clearance ◽  
Nasal Cannula ◽  
Compressed Air ◽  
Low Flow ◽  
Cross Sectional ◽  
Nasal Symptoms ◽  
Nasal Inflammation

AbstractSome clinical situations require the use of oxygen therapy for a few hours without hypoxemia. However, there are no literature reports on the effects of acute oxygen therapy on the nasal mucosa. This study aimed to evaluate the acute effects of cold bubble humidification or dry oxygen on nasal Inflammation, oxidative stress, mucociliary clearance, and nasal symptoms. This is a randomized controlled cross-sectional study in which healthy subjects were randomly allocated into four groups: (1) CA + DRY (n = 8): individuals receiving dry compressed air; (2) OX + DRY (n = 8): individuals receiving dry oxygen therapy; (3) CA + HUMID (n = 7): individuals receiving cold bubbled humidified compressed air; (4) OX + HUMID (n = 8): individuals receiving cold bubbled humidified oxygen therapy. All groups received 3 L per minute (LPM) of the oxygen or compressed air for 1 h and were evaluated: total and differential cells in the nasal lavage fluid (NLF), exhaled nitric oxide (eNO), 8-iso-PGF2α levels, saccharin transit test, nasal symptoms, and humidity of nasal cannula and mucosa. Cold bubble humidification is not able to reduced nasal inflammation, eNO, oxidative stress, mucociliary clearance, and nasal mucosa moisture. However, subjects report improvement of nasal dryness symptoms (P < 0.05). In the conclusion, cold bubble humidification of low flow oxygen therapy via a nasal cannula did not produce any effect on the nasal mucosa and did not attenuate the oxidative stress caused by oxygen. However, it was able to improve nasal symptoms arising from the use of oxygen therapy.

scholarly journals Nasal symptoms increase the risk of snoring and snoring increases the risk of nasal symptoms. A longitudinal population study

2021 ◽  
Author(s):  
Maria Värendh ◽  
Christer Janson ◽  
Caroline Bengtsson ◽  
Johan Hellgren ◽  
Mathias Holm ◽  
...  
Keyword(s):  
Risk Factors ◽  
Respiratory Health ◽  
Smoking Status ◽  
Northern Europe ◽  
Nasal Breathing ◽  
Nasal Symptoms ◽  
Increased Risk ◽  
Study Population ◽  
Independent Risk Factors

Abstract Purpose Humans have a preference for nasal breathing during sleep. This 10-year prospective study aimed to determine if nasal symptoms can predict snoring and also if snoring can predict development of nasal symptoms. The hypothesis proposed is that nasal symptoms affect the risk of snoring 10 years later, whereas snoring does not increase the risk of developing nasal symptoms. Methods In the cohort study, Respiratory Health in Northern Europe (RHINE), a random population from Denmark, Estonia, Iceland, Norway, and Sweden, born between 1945 and 1973, was investigated by postal questionnaires in 1999–2001 (RHINE II, baseline) and in 2010–2012 (RHINE III, follow-up). The study population consisted of the participants who had answered questions on nasal symptoms such as nasal obstruction, discharge, and sneezing, and also snoring both at baseline and at follow-up (n = 10,112). Results Nasal symptoms were frequent, reported by 48% of the entire population at baseline, with snoring reported by 24%. Nasal symptoms at baseline increased the risk of snoring at follow-up (adj. OR 1.38; 95% CI 1.22–1.58) after adjusting for age, sex, BMI change between baseline and follow-up, and smoking status. Snoring at baseline was associated with an increased risk of developing nasal symptoms at follow-up (adj. OR 1.22; 95% CI 1.02–1.47). Conclusion Nasal symptoms are independent risk factors for development of snoring 10 years later, and surprisingly, snoring is a risk factor for the development of nasal symptoms.

scholarly journals Can Sex Improve Nasal Function?—An Exploration of the Link Between Sex and Nasal Function

2021 ◽  
pp. 014556132098144
Author(s):  
Olcay Cem Bulut ◽  
Dare Oladokun ◽  
Burkard M. Lippert ◽  
Ralph Hohenberger
Keyword(s):  
Sexual Activity ◽  
Sexual Intercourse ◽  
Nasal Obstruction ◽  
Nasal Breathing ◽  
Post Intervention ◽  
Nasal Decongestant ◽  
Symptom Evaluation ◽  
Nasal Function ◽  
Nasal Flow ◽  
The Impact

Objectives: This study was conducted to examine the impact of sexual activity on nasal breathing and compare such effect to that of a nasal decongestant. Methods: We evaluated nasal breathing at 5 different times: (1) before sexual activity (baseline), (2) immediately after sexual activity, (3) 30 minutes, (4) 1 hour (5), and 3 hours after sexual climax. Same measurements were taken on the second day following application of nasal decongestant spray. For evaluation of nasal breathing, we used a visual analogue scale (VAS). Additionally, we used a portable rhinometric device to measure resistance and nasal flow. Results: Nasal breathing improved significantly after sexual intercourse with climax to the same degree as after application of nasal decongestant for up to 60 minutes, as measured subjectively with the VAS (sex −3.6, P < .001; spray −3.2, P < .001). This was confirmed in the objective rhinometric data as mean nasal flow (mL/s) increased while resistance decreased immediately (flow sex +214, P < .001; flow spray +235, P < .001), 30 (flow sex +249, P < .001; flow spray +287, P < .001), and 60 minutes (flow sex +180, P < .001; flow spray +287, P < .001) post-intervention. Nasal breathing was back to the baseline level after 3 hours following sexual intercourse, while it continued to be improved for longer after application of nasal decongestant. Only participants having nasal obstruction (Nasal Obstruction Symptom Evaluation score >30) showed nasal function improvement after sex. Conclusions: Sexual intercourse with climax can improve nasal breathing to the same degree as application of nasal decongestant for up to 60 minutes in patients having nasal obstruction.

Nasal challenge shows pathogenetic relevance of specific IgE serum antibodies for nasal symptoms caused by hexahydrophthalic anhydride

1994 ◽  
Vol 24 (5) ◽  
pp. 440-449 ◽  
Author(s):  
J. NIELSEN ◽  
. WELINDER ◽  
H. OTTOSSON ◽  
I. BENSRYD ◽  
P. VENGE ◽  
...  
Keyword(s):  
Specific Ige ◽  
Serum Antibodies ◽  
Nasal Challenge ◽  
Nasal Symptoms

Role of substance P in allergic nasal symptoms in rats

2006 ◽  
Vol 532 (1-2) ◽  
pp. 155-161 ◽  
Author(s):  
Md. Ashequr Rahman ◽  
Toshio Inoue ◽  
Chiaki Kamei
Keyword(s):  
Substance P ◽  
Nasal Symptoms

MP29-02 in the Treatment of Nasal Symptoms of Seasonal Allergic Rhinitis

2011 ◽  
Vol 127 (2) ◽  
pp. AB199-AB199
Author(s):  
W. Carr ◽  
S.R. Shah ◽  
W. Wheeler ◽  
H. Sacks
Keyword(s):  
Allergic Rhinitis ◽  
Seasonal Allergic Rhinitis ◽  
Nasal Symptoms

S103 – Mometasone Is Effective With or Without Oral Antihistamines

2008 ◽  
Vol 139 (2_suppl) ◽  
pp. P112-P112
Author(s):  
Joao Antonio Marta Pimentel
Keyword(s):  
Nasal Discharge ◽  
Daily Routine ◽  
Efficacy And Safety ◽  
Concomitant Therapy ◽  
Open Label ◽  
Daily Routines ◽  
Oral Antihistamine ◽  
Intranasal Corticosteroids ◽  
Nasal Symptoms ◽  
Symptom Scores

Objectives Clinical trials have demonstrated the efficacy of monotherapy with intranasal corticosteroids (INSs) for symptoms of allergic rhinitis (AR). ARIA guidelines suggest adding oral antihistamines to INS monotherapy when severe symptoms do not improve. An open-label multicenter study assessed efficacy and safety of mometasone furoate nasal spray (MFNS) alone or combined with an oral antihistamine in subjects with AR. Methods Subjects received MFNS 200 mcg QD for 56 days, with an oral antihistamine added at Day 28 or later if baseline symptoms (sneezing, nasal discharge/obstruction, tiredness, irritability) had not improved. Subjects rated individual symptom scores, daily routine and sleep limitations, and product attributes on Days 1, 28, and 56 on a scale of 0 to 10, and completed a compliance questionnaire on Day 56. Results Mean scores for AR symptoms and limitations on sleep and daily routines significantly improved from baseline to Day 28 and from Day 28 to 56 (P less than 0.001 for all). At Days 28 and 56, 47/60 and 45/56 subjects, respectively, were receiving MFNS monotherapy, and 13 required a concomitant oral antihistamine at Day 28 or later. By Day 56, symptom severity improved in 92% of subjects receiving concomitant therapy. At study end, 88% of subjects reported compliance with QD MFNS. Average product attribute scores ranged from 7.2 to 8.4. No severe adverse events were reported. Conclusions MFNS 200 mcg QD, alone or combined with an oral antihistamine, was safe and effective against AR nasal symptoms and limitations of sleep and daily activities.

Systemic Diseases Associated with Nasal Symptoms

1987 ◽  
Vol 1 (1) ◽  
pp. 33-44 ◽  
Author(s):  
Guy A. Settipane
Keyword(s):  
Differential Diagnosis ◽  
Fungal Infections ◽  
Systemic Disease ◽  
Systemic Diseases ◽  
Proper Treatment ◽  
Csf Rhinorrhea ◽  
Nasal Symptoms ◽  
Appropriate Treatment ◽  
Life Threatening ◽  
Careful History

Many systemic diseases are associated with nasal symptoms, Rhinitis associated with asthma is probably the most common with leprosy and fungal infections being the rarest. A careful history and nasal examination in a patient with rhinitis may lead to the discovery of more significant systemic diseases. Proper treatment of systemic disease will often cure or improve the associated rhinitis. Similarly, appropriate treatment of the rhinitis/sinusitis may reduce systemic complaints such as asthma. At times, identification of the cause of rhinitis as in CSF rhinorrhea, Wegeners’ syndrome, etc., alerts one to a life-threatening entity. Thus, it is apparent that the nose is an excellent mirror of some systemic diseases and identifying and understanding the differential diagnosis of nasal symptoms may be a tremendous help in diagnosing the disease and treating the whole patient.

scholarly journals Prevalence of nasal symptoms and their relation to self-reported asthma and chronic bronchitis/emphysema

2001 ◽  
Vol 17 (4) ◽  
pp. 596-603 ◽  
Author(s):  
P. Montnémery ◽  
C. Svensson ◽  
E. Ädelroth ◽  
C-G. Löfdahl ◽  
M. Andersson ◽  
...  
Keyword(s):  
Chronic Bronchitis ◽  
Nasal Symptoms
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