scholarly journals End-Tidal-to-Arterial PCO2 Ratio as Signifier for Physiologic Dead-Space Ratio and Oxygenation Dysfunction in Acute Respiratory Distress Syndrome

2020 ◽  
pp. respcare.08061
Author(s):  
Richard H Kallet ◽  
Michael S Lipnick
Keyword(s):  
Acute Respiratory Distress Syndrome ◽  
Respiratory Distress Syndrome ◽  
Respiratory Distress ◽  
Dead Space ◽  
Distress Syndrome ◽  
Arterial Pco2 ◽  
Physiologic Dead Space ◽  
End Tidal ◽  
Space Ratio

scholarly journals Dead space in acute respiratory distress syndrome

2018 ◽  
Vol 6 (19) ◽  
pp. 388-388 ◽  
Author(s):  
Massimo Ferluga ◽  
Umberto Lucangelo ◽  
Lluis Blanch
Keyword(s):  
Acute Respiratory Distress Syndrome ◽  
Respiratory Distress Syndrome ◽  
Respiratory Distress ◽  
Dead Space ◽  
Distress Syndrome

scholarly journals Estimating Dead-Space Fraction for Secondary Analyses of Acute Respiratory Distress Syndrome Clinical Trials

2015 ◽  
Vol 43 (5) ◽  
pp. 1026-1035 ◽  
Author(s):  
Jeremy R. Beitler ◽  
B. Taylor Thompson ◽  
Michael A. Matthay ◽  
Daniel Talmor ◽  
Kathleen D. Liu ◽  
...  
Keyword(s):  
Clinical Trials ◽  
Acute Respiratory Distress Syndrome ◽  
Respiratory Distress Syndrome ◽  
Respiratory Distress ◽  
Dead Space ◽  
Distress Syndrome ◽  
Secondary Analyses

Establishing a gradient between partial pressure of arterial carbon dioxide and end-tidal carbon dioxide in patients with acute respiratory distress syndrome

2016 ◽  
Vol 65 (2) ◽  
pp. 338-341 ◽  
Author(s):  
Tariq Yousuf ◽  
Taylor Brinton ◽  
Ghulam Murtaza ◽  
Daniel Wozniczka ◽  
Khansa Ahmad ◽  
...  
Keyword(s):  
Carbon Dioxide ◽  
Acute Respiratory Distress Syndrome ◽  
Respiratory Distress Syndrome ◽  
Respiratory Distress ◽  
Distress Syndrome ◽  
Statistical Significance ◽  
End Tidal Carbon Dioxide ◽  
The Mean ◽  
The Difference ◽  
End Tidal

End-tidal carbon dioxide (ETCO2) monitoring is useful in many situations. However, ETCO2 monitoring is unreliable in patients with acute respiratory distress syndrome (ARDS) due to widespread lung inflammation. In our study, we attempt to establish the gradient between the arterial pressure of carbon dioxide (PaCO2) and ETCO2 in patients with ARDS, which we defined as the PaETCO2 gradient. The main objective of the study was to establish a PaETCO2 gradient in each severity of ARDS. We analyzed 35 patients with ARDS and a total of 88 arterial blood gases were included. PaCO2, PaO2/FiO2 and ETCO2 were measured. Patients were stratified into mild, moderate and severe ARDS as classified by the Berlin ARDS criteria. PaCO2 and ETCO2 were compared at each severity stratification. The mean PaCO2 was 50.0, the mean ETCO2 was 26.6 and the gradient among all samples was 23.24 (±12.02). The mean gradient for each severity is as follows: mild: 19.3 (±9.9), moderate: 27.9 (±13.2) and severe: 23.9 (±7.8). The difference between the PaETCO2 gradient of the mild to moderate (p=0.001) and mild to severe groups (p=0.01) reached statistical significance. However, the difference between the moderate to severe groups did not reach statistical significance (p=0.48). We found the gradient between PaCO2 and ETCO2 in patients with ARDS is vast and tends to worsen with increasing severity of ARDS. This indicates that the gradient between the 2 may be used as an indicator of increasing severity of ARDS.

scholarly journals Potential Effects of Corticosteroids on Physiological Dead-Space Fraction in Acute Respiratory Distress Syndrome

2012 ◽  
Vol 57 (3) ◽  
pp. 377-383 ◽  
Author(s):  
J. M. Raurich ◽  
M. Ferreruela ◽  
J. A. Llompart-Pou ◽  
M. Vilar ◽  
A. Colomar ◽  
...  
Keyword(s):  
Acute Respiratory Distress Syndrome ◽  
Respiratory Distress Syndrome ◽  
Respiratory Distress ◽  
Dead Space ◽  
Distress Syndrome ◽  
Physiological Dead Space
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