scholarly journals Does the 25-OH-Vitamin D Level Affect the Insulin Resistance in the Patients with Non-Diabetic Chronic Kidney Disease?

2019 ◽  
Vol 15 (3) ◽  
pp. 360-363
Author(s):  
S Sezer
2011 ◽  
pp. 149-155 ◽  
Author(s):  
K. ŠTEFÍKOVÁ ◽  
V. SPUSTOVÁ ◽  
Z. KRIVOŠÍKOVÁ ◽  
A. OKŠA ◽  
K. GAZDÍKOVÁ ◽  
...  

Vitamin D status and the relationship between serum 25(OH) vitamin D concentrations and the components of insulin resistance were examined in 120 patients with chronic kidney disease stage 2 and 3. Insulin sensitivity/resistance was calculated by the quantitative insulin sensitivity check index (QUICKI). In this analysis, the prevalence of insulin resistance was 42 %. Only 17 % of patients had serum 25(OH) vitamin D concentration in the recommended range (≥30 ng/ml), 42 % suffered from vitamin D insufficiency and 41 % had moderate vitamin D deficiency. Insulin resistance significantly correlated with serum 25(OH)D and 1,25(OH)2D concentrations, renal function and protein excretion rate. Our results support the increasing evidence that vitamin D deficiency may be one of the factors participating in the development of insulin resistance already in the early stages of chronic kidney disease.


Author(s):  
Davendra Kumar ◽  
Ajay Kumar Mishra ◽  
Mehboob Subhani Siddiqui ◽  
Soubeer Ghosh ◽  
Shahnawaz Shahidali Jafri

2007 ◽  
Vol 11 (3) ◽  
pp. 315-321 ◽  
Author(s):  
Elisa DEL VALLE ◽  
Armando L. NEGRI ◽  
Cristina AGUIRRE ◽  
Erich FRADINGER ◽  
Jose R. ZANCHETTA

Renal Failure ◽  
2013 ◽  
Vol 36 (1) ◽  
pp. 58-64 ◽  
Author(s):  
Silvia Lai ◽  
Bettina Coppola ◽  
Mira Dimko ◽  
Alessandro Galani ◽  
Georgie Innico ◽  
...  

2011 ◽  
Vol 2011 ◽  
pp. 1-4 ◽  
Author(s):  
Subhashini Yaturu ◽  
Jared Davis

Objective. Vitamin D deficiency is associated with a variety of skeletal and extraskeletal problems. The aim of this study was to evaluate the prevalence of vitamin D deficiency among veterans in sunny Louisiana. Methods. Using the VA computerized patient record system, we searched for all 25 (OH) Vitamin D and 1, 25 (OH) vitamin D levels that were measured between 2007 and 2009. The information collected for each patient included age, body mass index, creatinine, history of diabetes and hypertension, and levels of vitamin D and PTH. We determined the number of individuals who were vitamin D insufficient and deficient. Results. Among 2990 studies evaluated, the mean concentration of 25 (OH) D was  ng/mL, and that of 1, 25 (OH) vitamin D was  ng/mL. Among them, only 695 subjects (23%) had normal values, while 889 (30%) had insufficiency, and 1405 (47%) had deficiency. Subjects with diabetes (1041) had significantly () lower levels (21 and 25 ng/mL) of both 25 (OH) and 1,25 (OH) vitamin D compared to subjects without diabetes (23 and 32 ng/mL). Similarly, subjects with chronic kidney disease (1128) had much lower vitamin D levels than subjects without CKD. Among subjects with diabetes, those with chronic kidney disease (512) had much lower levels of both 25 (OH) and 1,25 (OH) vitamin D than with those with normal creatinine levels. Conclusions. We conclude that vitamin D insufficiency and deficiency is highly prevalent in veterans, more so among subjects with diabetes and/or CKD.


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