Morphological Evidence for a Intrinsic Angiotensin System in the Bovine Pineal Gland

2006 ◽  
Vol 2 (4) ◽  
pp. 389-401
Author(s):  
Corin Badiu
1979 ◽  
Vol 29 (2) ◽  
pp. 84-89 ◽  
Author(s):  
Maria I. Vacas ◽  
Pedro R. Lowenstein ◽  
Daniel P. Cardinali

1958 ◽  
Vol 36 (2) ◽  
pp. 227-235 ◽  
Author(s):  
Enrique Santamarina

The incidence of melanin in the bovine pineal gland was studied in 880 glands. Spectrophotometric analysis and chemical and cytochemical methods identified the black pigment present in the bovine pineal gland as melanin. No melanin was found in bulls 4 and 5 years of age nor in heifers of about 18 months. In pregnant cows over 5 years of age melanin was found in 5.4% of the pineal glands. Non-pregnant cows of the same age exhibited melanin in 8.5% of the pineal glands. Castrated male cattle between 18 and 24 months of age showed 49.6% of the pineal glands with macroscopical signs of melanization. As much as 67% of the pineal glands of steers from some herds contained melanin. In intact cattle melanin in the pineal appears to be mainly an aging phenomenon. The fact that castration in male cattle causes hypertrophy of the pineal gland followed by a degenerative process in which melanin is involved seems to give strong evidence of a pineal gonadal interrelationship. The possible role of the hormones in the phenomenon of melanin formation is discussed.


1992 ◽  
Vol 13 (3) ◽  
pp. 124-132 ◽  
Author(s):  
P. Govitrapong ◽  
M. Pariyanonth ◽  
M. Ebadi

1974 ◽  
Vol 147 (2) ◽  
pp. 438-440 ◽  
Author(s):  
D. W. Cheesman ◽  
P. H. Forsham

Author(s):  
Tarun Minocha ◽  
Megha Das ◽  
Nitesh Kumar Mishra ◽  
Soumya Ranjan Mohanty ◽  
Sanjeev Kumar Yadav

2010 ◽  
Vol 298 (5) ◽  
pp. R1143-R1155 ◽  
Author(s):  
Fiona Hanner ◽  
Charlotte Mehlin Sorensen ◽  
Niels-Henrik Holstein-Rathlou ◽  
János Peti-Peterdi

Connexins (Cxs) are widely-expressed proteins that form gap junctions in most organs, including the kidney. In the renal vasculature, Cx37, Cx40, Cx43, and Cx45 are expressed, with predominant expression of Cx40 in the endothelial cells and Cx45 in the vascular smooth muscle cells. In the tubules, there is morphological evidence for the presence of gap junction plaques only in the proximal tubules. In the distal nephron, Cx30, Cx30.3, and Cx37 are expressed, but it is not known whether they form gap junctions connecting neighboring cells or whether they primarily act as hemichannels. As in other systems, the major function of Cxs in the kidney appears to be intercellular communication, although they may also form hemichannels that allow cellular secretion of large signaling molecules. Renal Cxs facilitate vascular conduction, juxtaglomerular apparatus calcium signaling, and tubular purinergic signaling. Accordingly, current evidence points to roles for these Cxs in several important regulatory mechanisms in the kidney, including the renin angiotensin system, tubuloglomerular feedback, and salt and water reabsorption. At the systemic level, renal Cxs may help regulate blood pressure and may be involved in hypertension and diabetes.


1989 ◽  
Vol 77 (2-3) ◽  
pp. 141-152 ◽  
Author(s):  
Ruth E. Rosenstein ◽  
Claudia Sanjurjo ◽  
D. P. Cardinali

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