scholarly journals Proton Pump Inhibitors and Lower Serum Ferritin Levels in 171 HFE C282Y Homozygotes in the Hemochromatosis and Iron Overload Screening Study

2013 ◽  
Vol 02 (02) ◽  
Author(s):  
James C Barton ◽  
Paul C Adams
Keyword(s):  
Iron Overload ◽  
Serum Ferritin ◽  
Proton Pump Inhibitors ◽  
Proton Pump ◽  
Lower Serum ◽  
Screening Study

scholarly journals Serum ferritin is a biomarker for liver mortality in the Hemochromatosis and Iron Overload Screening Study

2015 ◽  
Vol 14 (3) ◽  
pp. 348-353 ◽  
Author(s):  
Paul C. Adams ◽  
James C. Barton ◽  
Helen Guo ◽  
David Alter ◽  
Mark Speechley
Keyword(s):  
Iron Overload ◽  
Serum Ferritin ◽  
Screening Study

Serial serum ferritin measurements in untreatedHFEC282Y homozygotes in the Hemochromatosis and Iron Overload Screening Study

2008 ◽  
Vol 30 (4) ◽  
pp. 300-305 ◽  
Author(s):  
P. C. ADAMS ◽  
D. M. REBOUSSIN ◽  
J. C. BARTON ◽  
R. T. ACTON ◽  
M. SPEECHLEY ◽  
...  
Keyword(s):  
Iron Overload ◽  
Serum Ferritin ◽  
Screening Study ◽  
Serial Serum

scholarly journals HFEMutations in Caucasian Participants of the Hemochromatosis and Iron Overload Screening Study with Serum Ferritin Level <1000 μg/L

2013 ◽  
Vol 27 (7) ◽  
pp. 390-392 ◽  
Author(s):  
Paul C Adams ◽  
Christine E McLaren ◽  
Mark Speechley ◽  
Gordon D McLaren ◽  
James C Barton ◽  
...  
Keyword(s):  
Iron Overload ◽  
Serum Ferritin ◽  
Serum Ferritin Level ◽  
Ferritin Level ◽  
Transferrin Saturation ◽  
Elevated Serum ◽  
Population Based ◽  
Ferritin Concentration ◽  
Post Test ◽  
Screening Study

BACKGROUND: Many patients referred for an elevated serum ferritin level <1000 μg/L are advised that they likely have iron overload and hemochromatosis.AIMS: To determine the prevalence ofHFEmutations in the hemochromatosis gene for 11 serum ferritin concentration intervals from 200 μg/L to 1000 μg/L in Caucasian participants in a primary care, population-based study.METHODS: The Hemochromatosis and Iron Overload Screening study screened 99,711 participants for serum ferritin levels, transferrin saturation and genetic testing for the C282Y and H63D mutations of theHFEgene. This analysis was confined to 17,160 male and 27,465 female Caucasian participants because theHFEC282Y mutation is rare in other races. Post-test likelihood was calculated for prediction of C282Y homozygosity from a ferritin interval. A subgroup analysis was performed in participants with both an elevated serum ferritin level and transferrin saturation.RESULTS: There were 3359 male and 2416 female participants with an elevated serum ferritin level (200 μg/L to 1000 μg/L for women, 300 μg/L to 1000 μg/L for men). There were 69 male (2.1%) and 87 female (3.6%) C282Y homozygotes, and the probability of being a homozygote increased as the ferritin level increased. Post-test likelihood values were 0.3% to 16% in men and 0.3% to 30.4% in women.CONCLUSIONS: Iron loadingHFEmutations are unlikely to be the most common cause of an elevated serum ferritin level in patients with mild hyperferritinemia. Patients should be advised that there are many causes of an elevated serum ferritin level including iron overload.

Initial Screening Transferrin Saturation Values, Serum Ferritin Concentrations, andHFEGenotypes in Whites and Blacks in the Hemochromatosis and Iron Overload Screening Study

2005 ◽  
Vol 9 (3) ◽  
pp. 231-241 ◽  
Author(s):  
James C. Barton ◽  
Ronald T. Acton ◽  
Fitzroy W. Dawkins ◽  
Paul C. Adams ◽  
Laura Lovato ◽  
...  
Keyword(s):  
Iron Overload ◽  
Serum Ferritin ◽  
Transferrin Saturation ◽  
Initial Screening ◽  
Screening Study

Inhibitory effect of proton pump inhibitors against chemotaxis of Helicobacter pylori

2001 ◽  
Vol 120 (5) ◽  
pp. A655-A656
Author(s):  
H NAKAMURA ◽  
H YOSHIYAMA ◽  
H YANAI ◽  
M SHIRAL ◽  
T NAKAZAWA ◽  
...  
Keyword(s):  
Helicobacter Pylori ◽  
Proton Pump Inhibitors ◽  
Proton Pump ◽  
Inhibitory Effect

Abstract #728: Severe Hypomagnesemia and Breakthrough Seizure with Proton Pump Inhibitors Use

2015 ◽  
Vol 21 ◽  
pp. 139
Author(s):  
Muhammad Mahmood ◽  
Andrew Kinch ◽  
Woodall Brittany ◽  
Ayman Elkadry
Keyword(s):  
Proton Pump Inhibitors ◽  
Proton Pump ◽  
Breakthrough Seizure

Abstract #713 Proton Pump Inhibitors and Hypocalcemia: Does it Really Happen?

2018 ◽  
Vol 24 ◽  
pp. 157-158
Author(s):  
Franco Vallejo Garcia ◽  
Melissa Sum
Keyword(s):  
Proton Pump Inhibitors ◽  
Proton Pump

Erratum: Overutilization of Proton Pump Inhibitors: A Review of Cost-Effectiveness and Risk in PPI

2009 ◽  
Vol 104 (4) ◽  
pp. 1072-1072
Author(s):  
Joel J Heidelbaugh ◽  
Kathleen L Goldberg ◽  
John M Inadomi
Keyword(s):  
Cost Effectiveness ◽  
Proton Pump Inhibitors ◽  
Proton Pump
Sign in / Sign up

Export Citation Format

Share Document