scholarly journals Size-dependent Bacterial Growth Inhibition and Antibacterial Activity of Ag-doped ZnO Nanoparticles under Different Atmospheric Conditions

2018 ◽  
Vol 80 (01) ◽  
Author(s):  
S Shahid ◽  
S A Khan ◽  
W Ahmad ◽  
U Fatima ◽  
S Knawal
Keyword(s):  
Antibacterial Activity ◽  
Growth Inhibition ◽  
Bacterial Growth ◽  
Zno Nanoparticles ◽  
Atmospheric Conditions ◽  
Size Dependent ◽  
Doped Zno ◽  
Bacterial Growth Inhibition

scholarly journals In vitro evaluation of antibacterial efficacy of vancomycin-loaded suture tapes and cerclage wires

2021 ◽  
Vol 32 (4) ◽  
Author(s):  
Annette Eidmann ◽  
Andrea Ewald ◽  
Sebastian P. Boelch ◽  
Maximilian Rudert ◽  
Boris M. Holzapfel ◽  
...  
Keyword(s):  
Antibacterial Activity ◽  
Growth Inhibition ◽  
Bacterial Growth ◽  
Orthopedic Surgery ◽  
Steel Wire ◽  
Antibacterial Efficacy ◽  
Polyester Suture ◽  
Agar Diffusion Test ◽  
Bacterial Growth Inhibition

AbstractUsage of implants containing antibiotic agents has been a common strategy to prevent implant related infections in orthopedic surgery. Unfortunately, most implants with microbial repellent properties are characterized by accessibility limitations during daily clinical practice. Aim of this in vitro study was to investigate whether suture tapes and cerclage wires, which were treated with vancomycin, show a sustainable antibacterial activity. For this purpose, we used 24 stainless steel wire cerclages and 24 ultra-high molecular weight polyethylene and polyester suture tape test bodies. The test bodies were incubated for 30 min. in 100 mg/ml vancomycin solution or equivalent volumes of 0.9% NaCl. After measuring the initial solution uptake of the test bodies, antibacterial efficacy via agar diffusion test with Staphylococcus aureus and vancomycin elution tests were performed 1, 2, 3, and 6 days after incubation. Vancomycin-loaded tapes as well as vancomycin-loaded cerclage wires demonstrated increased bacterial growth inhibition when compared to NaCl-treated controls. Vancomycin-loaded tapes showed an additional twofold and eightfold increase of bacterial growth inhibition compared to vancomycin-loaded wires at day 1 and 2, respectively. Elution tests at day 1 revealed high levels of vancomycin concentration in vancomycin loaded tapes and wires. Additionally, the concentration in vancomycin loaded tapes was 14-fold higher when compared to vancomycin loaded wires. Incubating suture tapes and cerclage wires in vancomycin solution showed a good short-term antibacterial activity compared to controls. Considering the ease of vancomycin application on suture tapes or wires, our method could represent an attractive therapeutic strategy in biofilm prevention in orthopedic surgery.

scholarly journals Reversal by Ribonucleosides of Bacterial Growth Inhibition Caused by Alcohol

1960 ◽  
Vol 235 (12) ◽  
pp. 3551-3555
Author(s):  
Edwin M. Lansford ◽  
Ira D. Hill ◽  
William Shive
Keyword(s):  
Growth Inhibition ◽  
Bacterial Growth ◽  
Bacterial Growth Inhibition

Synergetic effect of Sn doped ZnO nanoparticles synthesized via ultrasonication technique and its photocatalytic and antibacterial activity

2021 ◽  
pp. 111115
Author(s):  
Steplinpaulselvin Selvinsimpson ◽  
Gnanamozhi P ◽  
Pandiyan V ◽  
Mani Govindasamy ◽  
Mohamed A. Habila ◽  
...  
Keyword(s):  
Antibacterial Activity ◽  
Zno Nanoparticles ◽  
Synergetic Effect ◽  
Doped Zno

scholarly journals Natural Product Rottlerin Derivatives Targeting Quorum Sensing

Molecules ◽  
2021 ◽  
Vol 26 (12) ◽  
pp. 3745
Author(s):  
Dittu Suresh ◽  
Shekh Sabir ◽  
Tsz Tin Yu ◽  
Daniel Wenholz ◽  
Theerthankar Das ◽  
...  
Keyword(s):  
Pseudomonas Aeruginosa ◽  
Quorum Sensing ◽  
Growth Inhibition ◽  
Natural Product ◽  
Bacterial Growth ◽  
Inhibitory Activity ◽  
Chalcone Derivatives ◽  
Synthetic Strategy ◽  
The Mannich Reaction ◽  
Bacterial Growth Inhibition

Rottlerin is a natural product consisting of chalcone and flavonoid scaffolds, both of which have previously shown quorum sensing (QS) inhibition in various bacteria. Therefore, the unique rottlerin scaffold highlights great potential in inhibiting the QS system of Pseudomonas aeruginosa. Rottlerin analogues were synthesised by modifications at its chalcone- and methylene-bridged acetophenone moieties. The synthesis of analogues was achieved using an established five-step synthetic strategy for chalcone derivatives and utilising the Mannich reaction at C6 of the chromene to construct morpholine analogues. Several pyranochromene chalcone derivatives were also generated using aldol conditions. All the synthetic rottlerin derivatives were screened for QS inhibition and growth inhibition against the related LasR QS system. The pyranochromene chalcone structures displayed high QS inhibitory activity with the most potent compounds, 8b and 8d, achieving QS inhibition of 49.4% and 40.6% and no effect on bacterial growth inhibition at 31 µM, respectively. Both compounds also displayed moderate biofilm inhibitory activity and reduced the production of pyocyanin.

Towards understanding the enhancement of antibacterial activity in manganese doped ZnO nanoparticles

2019 ◽  
Vol 471 ◽  
pp. 960-972 ◽  
Author(s):  
Amalia Mesaros ◽  
Bogdan S. Vasile ◽  
Dana Toloman ◽  
Oana Lelia Pop ◽  
Traian Marinca ◽  
...  
Keyword(s):  
Antibacterial Activity ◽  
Zno Nanoparticles ◽  
Doped Zno

scholarly journals Anthocyanin Incorporated Dental Copolymer: Bacterial Growth Inhibition, Mechanical Properties, and Compound Release Rates and Stability by1H NMR

2014 ◽  
Vol 2014 ◽  
pp. 1-6 ◽  
Author(s):  
Halyna Hrynash ◽  
Vinay Kumar Pilly ◽  
Alexandra Mankovskaia ◽  
Yaoyang Xiong ◽  
Getulio Nogueira Filho ◽  
...  
Keyword(s):  
Mechanical Properties ◽  
Growth Inhibition ◽  
Bacterial Growth ◽  
Testing Machine ◽  
Control Group ◽  
Uv Spectrophotometry ◽  
Release Rates ◽  
H Nmr ◽  
Colony Forming Units ◽  
Bacterial Growth Inhibition

Objective.To evaluate bacterial growth inhibition, mechanical properties, and compound release rate and stability of copolymers incorporated with anthocyanin (ACY;Vaccinium macrocarpon).Methods.Resin samples were prepared (Bis-GMA/TEGDMA at 70/30 mol%) and incorporated with 2 w/w% of either ACY or chlorhexidine (CHX), except for the control group. Samples were individually immersed in a bacterial culture (Streptococcus mutans) for 24 h. Cell viability (n=3) was assessed by counting the number of colony forming units on replica agar plates. Flexural strength (FS) and elastic modulus (E) were tested on a universal testing machine (n=8). Compound release and chemical stability were evaluated by UV spectrophotometry and1H NMR (n=3). Data were analyzed by one-way ANOVA and Tukey’s test (α= 0.05).Results.Both compounds inhibited S. mutans growth, with CHX being most effective (P<0.05). Control resin had the lowest FS and E values, followed by ACY and CHX, with statistical difference between control and CHX groups for both mechanical properties (P<0.05). The 24 h compound release rates were ACY: 1.33 μg/mL and CHX: 1.92 μg/mL.1H NMR spectra suggests that both compounds remained stable after being released in water.Conclusion.The present findings indicate that anthocyanins might be used as a natural antibacterial agent in resin based materials.

Sign in / Sign up

Export Citation Format

Share Document