scholarly journals Protective Effect of Naringin against Pylorus Ligation-induced Esophagitis in Male Wistar Rats

2017 ◽  
Vol 79 (02) ◽  
Author(s):  
C Shalini ◽  
P Kumar ◽  
K A. Singh ◽  
R Vinit ◽  
R Amit ◽  
...  
Keyword(s):  
Protective Effect ◽  
Wistar Rats ◽  
Pylorus Ligation ◽  
Male Wistar Rats

scholarly journals Protective effect of antioxidant rich aqueous curry leaf ( Murraya koenigii ) extract against gastro-toxic effects of piroxicam in male Wistar rats

2014 ◽  
Vol 1 ◽  
pp. 987-1003 ◽  
Author(s):  
Syed Benazir Firdaus ◽  
Debosree Ghosh ◽  
Aindrila Chattyopadhyay ◽  
Mousumi Dutta ◽  
Sudeshna Paul ◽  
...  
Keyword(s):  
Protective Effect ◽  
Wistar Rats ◽  
Toxic Effects ◽  
Murraya Koenigii ◽  
Male Wistar Rats

scholarly journals Protective effect of morin on cardiac mitochondrial function during isoproterenol-induced myocardial infarction in male Wistar rats

Redox Report ◽  
2012 ◽  
Vol 17 (1) ◽  
pp. 14-21 ◽  
Author(s):  
Khalid S. Al Numair ◽  
Govindasamy Chandramohan ◽  
Mohammed A. Alsaif ◽  
Arul Albert Baskar
Keyword(s):  
Myocardial Infarction ◽  
Protective Effect ◽  
Mitochondrial Function ◽  
Wistar Rats ◽  
Male Wistar Rats

scholarly journals Protective Effect of Terminalia arjuna Against DBTC Induced Pancreatic Cancer in Male Wistar Rats

2021 ◽  
pp. 248-256
Author(s):  
Kadiyala Harshitha ◽  
Uma Sankar Gorla
Keyword(s):  
Pancreatic Cancer ◽  
Body Weight ◽  
Protective Effect ◽  
Wistar Rats ◽  
Negative Control ◽  
Terminalia Arjuna ◽  
Hydroalcoholic Extract ◽  
Group I ◽  
Male Wistar Rats ◽  
Per Oral

Aims: To study the protective effect of hydroalcoholic bark extract of Terminalia arjuna against DBTC induced pancreatic cancer in male wistar rats. Study design: Healthy male Wistar Albino rats weighing 150-200 g were segregated into four groups (n=6). Group I was considered as normal control, received normal saline (0.9%w/v, 1 ml/kg body weight, orally). Group II rats were treated with DBTC (6 mg/kg body weight, i.p.) which served as negative control. Group III and IV received Terminalia arjuna Linn bark hydroalcoholic extract at doses of 250 mg/kg body weight, per oral and 500 mg/kg body weight, per oral respectively. Place and Duration of Study: University College of Pharmaceutical Sciences, Andhra University, Visakhapatnam, Andhra Pradesh, India, between May 2020 and July 2020. Methodology: The experimental animals were segregated into four groups of six rats each. According to acute toxicity data, 250 mg/kg as low dose and 500 mg/kg as high dose of the test compound have been chosen for administration. All the drugs were given for 28 consecutive days to all the respective groups with standard pellet diet and water ad libitum. The assessment of serum parameters such as α-Amylase, Lipase and blood glucose levels were carried out on 1st day, 14th day and 28th day to the respective groups. Results: Pretreated groups of Terminalia arjuna Linn bark hydroalcoholic extract (250 mg/kg and 500 mg/kg body weight, orally) showed significant (‘#’p<0.001) decrease in the levels of α-Amylase, Lipase and glucose in the blood when compared to DBTC (6 mg/kg body weight, i.p.) induced group which served as negative control. Conclusion: This study suggests that Terminalia arjuna may have a protective role against DBTC induced pancreatic cancer in male wistar rats and further investigation may be required to confirm its therapeutic potentials clinically.

scholarly journals Protective effect of Salvia officinalis against cypermethrininduced reprotoxicity in male Wistar rats

2021 ◽  
Vol 13 (6) ◽  
pp. 1413-1421
Author(s):  
Amel Chouabia ◽  
Samir Djemli ◽  
Cherif Abdennour ◽  
Leila Mallem ◽  
Labiba Kahalerras ◽  
...  
Keyword(s):  
Protective Effect ◽  
Wistar Rats ◽  
Salvia Officinalis ◽  
Male Wistar Rats

scholarly journals Protective effect of vitamin C on chronic carbamazepine-induced reproductive toxicity in male wistar rats

2020 ◽  
Vol 7 ◽  
pp. 269-276 ◽  
Author(s):  
Ganiu Jimoh Akorede ◽  
Suleiman Folorusho Ambali ◽  
Mikai’l Garba Hudu ◽  
Aisha Omobolanle Olatunji ◽  
Muftau Shittu ◽  
...  
Keyword(s):  
Vitamin C ◽  
Protective Effect ◽  
Wistar Rats ◽  
Reproductive Toxicity ◽  
Male Wistar Rats

scholarly journals Protective Effect of Repeatedly Preadministered Brazilian Propolis Ethanol Extract against Stress-Induced Gastric Mucosal Lesions in Rats

2014 ◽  
Vol 2014 ◽  
pp. 1-10 ◽  
Author(s):  
Tadashi Nakamura ◽  
Yoshiji Ohta ◽  
Kumiko Ikeno ◽  
Koji Ohashi ◽  
Takeyuki Ikeno
Keyword(s):  
Protective Effect ◽  
Restraint Stress ◽  
Wistar Rats ◽  
Water Immersion ◽  
Ethanol Extract ◽  
Neutrophil Infiltration ◽  
Gastric Mucosal Lesions ◽  
Male Wistar Rats ◽  
Mucosal Lesions ◽  
Brazilian Propolis

The present study was conducted to clarify the protective effect of Brazilian propolis ethanol extract (BPEE) against stress-induced gastric mucosal lesions in rats. The protective effect of BPEE against gastric mucosal lesions in male Wistar rats exposed to water-immersion restraint stress (WIRS) for 6 h was compared between its repeated preadministration (50 mg/kg/day, 7 days) and its single preadministration (50 mg/kg). The repeated BPEE preadministration attenuated WIRS-induced gastric mucosal lesions and gastric mucosal oxidative stress more largely than the single BPEE preadministration. In addition, the repeated BPEE preadministration attenuated neutrophil infiltration in the gastric mucosa of rats exposed to WIRS. The protective effect of the repeated preadministration of BPEE against WIRS-induced gastric mucosal lesions was similar to that of a single preadministration of vitamin E (250 mg/kg) in terms of the extent and manner of protection. From these findings, it is concluded that BPEE preadministered in a repeated manner protects against gastric mucosal lesions in rats exposed to WIRS more effectively than BPEE preadministered in a single manner possibly through its antioxidant and anti-inflammatory actions.

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