Evaluation of Intraperitoneal and Port Site Infiltration of Bupivacaine in Combination with Fentanyl for Management of Postoperative Pain following Laparoscopic Cholecystectomy: A Double Blind Randomized Study

2015 ◽  
Vol 105 (05) ◽  
Author(s):  
Kedar S. Shahi ◽  
Geeta Bhandari
Keyword(s):  
Laparoscopic Cholecystectomy ◽  
Postoperative Pain ◽  
Randomized Study ◽  
Port Site ◽  
Double Blind

scholarly journals Pre-emptive analgesia VS Prophylactic analgesia and its influence on postoperative pain in postoperative laparoscopic cholecystectomy patients

2020 ◽  
Vol 1 (2) ◽  
pp. 038-043
Author(s):  
María Fernanda Maya Guerrero ◽  
Fabiola María Nuccio Giordano ◽  
Bernardo José Gutiérrez Sougarret ◽  
Alejandro Díaz Girón Gidi
Keyword(s):  
Laparoscopic Cholecystectomy ◽  
Postoperative Pain ◽  
Total Dose ◽  
Pain Control ◽  
Randomized Study ◽  
Pain Scale ◽  
Postoperative Pain Control ◽  
Double Blind ◽  
The Moment

Introduction: There are no studies on the use of dexketoprofen for postoperative pain control in patients undergoing laparoscopic cholecystectomy. Purpose: To assess if the timing of dexketoprofen administration influences the intensity of postoperative pain in patients undergoing laparoscopic cholecystectomy. Materials and methods used: Experimental, longitudinal, double-blind, randomized study. 50 mg of dexketoprofen diluted in 50 ml of 0.9% saline was administered to 50 patients divided into two groups: Pre-operative group: the substance was administered one hour before the beginning of surgery. Trans-operative group: the substance was administered at the moment when the gallbladder was separated from the liver base. The Numerical Pain Scale was evaluated and the number of doses and the total dose of tramadol that the patients received as analgesic rescue was quantified. Results: Administration of dexketoprofen before starting laparoscopic cholecystectomy tends to reduce the intensity of postoperative pain without being statistically significant. Conclusion: The timing of dexketoprofen administration has no impact on postoperative pain in patients operated for laparoscopic cholecystectomy.

scholarly journals Comparison of the Perioperative and Postoperative Effects of Levobupivacaine and of Levobupivacaine + Adrenaline in Pediatric Tonsillectomy: A Double-Blind Randomized Study

2017 ◽  
Vol 2017 ◽  
pp. 1-7 ◽  
Author(s):  
Faruk Cicekci ◽  
Cigdem Sizer ◽  
Sait Selcuk Atici ◽  
Sule Arican ◽  
Adnan Karaibrahimoglu ◽  
...  
Keyword(s):  
Postoperative Pain ◽  
Randomized Study ◽  
Oral Intake ◽  
Postoperative Nausea And Vomiting ◽  
Trial Registry ◽  
Zealand Clinical Trial Registry ◽  
Clinical Trial Registry ◽  
Double Blind ◽  
Total Consumption ◽  
Pain Scores

Objectives. We aimed to assess the effects of levobupivacaine and of levobupivacaine + adrenaline administered during pediatric tonsillectomy on the postoperative period. Methods. A total of 90 patients between the ages of five and twelve were divided randomly into two groups before tonsillectomy: levobupivacaine only (0.5%) 0.4 mg·kg−1 or levobupivacaine (0.5%) 0.4 mg·kg−1 + adrenaline (1 : 200.000) administered by means of peritonsillar infiltration. Primary outcomes were postoperative pain scores recorded at various intervals until 24 hours postoperatively. Secondary outcomes included postoperative nausea and vomiting (PONV), time to first oral intake, time to the first administration of analgesics and total consumption of analgesics, and the amount of bleeding for all children. Results. In both groups, patients had the same postoperative pain scores and PONV rates, and equal amounts of analgesics were consumed up to 24 hours postoperatively. The two groups also had the same time until first oral intake, recovery time and time to the first analgesic request, and amount of bleeding. Conclusions. Perioperative levobupivacaine infiltration on its own is a valid alternative to the combination of levobupivacaine + adrenaline for perioperative and postoperative effectiveness in pediatric tonsillectomy. This trial is registered with Australian New Zealand Clinical Trial Registry ACTRN: ACTRN12617001167358.

scholarly journals Effect of laparoscopic cholecystectomy techniques on postoperative pain: a prospective randomized study

2013 ◽  
Vol 85 (4) ◽  
pp. 149 ◽  
Author(s):  
Huseyin Yilmaz ◽  
Oguzhan Arun ◽  
Seza Apiliogullari ◽  
Fahrettin Acar ◽  
Husnu Alptekin ◽  
...  
Keyword(s):  
Laparoscopic Cholecystectomy ◽  
Postoperative Pain ◽  
Randomized Study ◽  
Prospective Randomized Study

scholarly journals Port Site Infiltration and Intraperitoneal Instillation of Bupivacaine for Post Operative Analgesia in Laparoscopic Cholecystectomy

2020 ◽  
Vol 14 (2) ◽  
pp. 58-61 ◽  
Author(s):  
Lipika Sanjowal ◽  
Swapan Kumar Biswas
Keyword(s):  
Laparoscopic Cholecystectomy ◽  
Postoperative Pain ◽  
Study Groups ◽  
Treatment Method ◽  
Port Site ◽  
Control Group ◽  
Vas Score ◽  
Intraperitoneal Instillation ◽  
Elective Laparoscopic Cholecystectomy ◽  
Experimental Group

Laparoscopic cholecystectomy has become the gold standard treatment method for symptomatic gallstone diseases. However pain is the only complaint that delays the discharge. This study aimed to evaluate the efficacy of bupivacaine infiltration into port site and instillation into peritoneal cavity to reduce pain following laparoscopic cholecystectomy. One hundred patients underwent elective laparoscopic cholecystectomy enrolled in this study. Patients were divided into experimental group (Group A) and control group (Group B) of 50 patients each. Following removal of gallbladder, patients of experimental group received 20 ml of 0.5% bupivacaine in gallbladder bed and 20 ml of 0.5% bupivacaine was infiltrated into 4 port sites. Control group received no treatment. The evaluation of postoperative pain was done at 4, 8, 12 and 24 hours postoperatively by using Visual Analogue Scale and the dose of NSAID was also recorded. Mean VAS score at 4, 8 and 12 hours postoperatively in experimental group was less than that of the control group (p<0.05). VAS score at 24 hours postoperatively did not differ between two study groups (p>0.05). The mean total NSAID doses used during first 24 hours postoperatively was less in the experimental group than control group (p<0.05). The localization of pain during first 24 hours postoperatively was 62% incisional, 29% intra abdominal and shoulder tip pain 9%. Port site infiltration and intraperitoneal instillation of bupivacaine following laparoscopic cholecystectomy reduce pain following laparoscopic cholecystectomy and this simple, inexpensive and effective method should be practiced to minimize early postoperative pain for all elective laparoscopic cholecystectomy. Faridpur Med. Coll. J. Jul 2019;14(2): 58-61

scholarly journals Third Molar Extraction: Irrigation and Cooling with Water or Sterile Physiological Solution: A Double-Blind Randomized Study

2021 ◽  
Vol 9 (4) ◽  
pp. 40
Author(s):  
Luca Sbricoli ◽  
Alessia Cerrato ◽  
Anna Chiara Frigo ◽  
Gastone Zanette ◽  
Christian Bacci
Keyword(s):  
Postoperative Pain ◽  
Randomized Study ◽  
Third Molar ◽  
Physiological Solution ◽  
Wilcoxon Test ◽  
University Hospital ◽  
Double Blind ◽  
Third Molar Extraction ◽  
Surgical Field ◽  
Molar Extraction

Background: The present study aimed to ascertain whether any significant reduction in patients’ postoperative pain and inflammation could be achieved by using sterile physiological solution instead of normal water to irrigate the surgical field and cool the dental bur during third molar extractions. Methods: The study concerned 22 patients (11 females and 11 males) in good general health, who were referred to the Dental Clinic at Padova University hospital for lower third molar extractions. They were randomly assigned to two groups. Only the fluid used to irrigate the surgical field and cool the dental bur differed between the two study groups, being sterile physiological solution for group A, and mains water for group B. Postoperative pain, swelling, trismus and inflammation with high sensitivity CRP where measured and statistically evaluated. The numerosity of our sample was calculated on the grounds of an endpoint based on data in the literature. Results: Eighteen patients needed bilateral extractions, and 4 required only one extraction, so a total of 40 third molars were extracted. A sterile physiological solution was used to irrigate the surgical field in 20 extractions, while water was used in the other 20 cases. Data analysis with Wilcoxon test show no differences between the two groups (p < 0.05). Conclusions: no differences between groups for any of the parameters considered, after third molar extraction procedures undertaken using either sterile physiological solution or water for irrigation and cooling purposes.

scholarly journals Port Site and Intraperitoneal Infiltration of Local Anesthetics in Reduction of Postoperative Pain after Laparoscopic Cholecystectomy

1970 ◽  
Vol 22 (1) ◽  
pp. 24-28 ◽  
Author(s):  
Mohammad Shaha Alam ◽  
Hasnat Waheedul Hoque ◽  
Mohammad Saifullah ◽  
Md Omar Ali
Keyword(s):  
Laparoscopic Cholecystectomy ◽  
Postoperative Pain ◽  
Open Cholecystectomy ◽  
Early Postoperative Period ◽  
Port Site ◽  
Control Group ◽  
Time Interval ◽  
Narcotic Analgesics ◽  
Pain Scores ◽  
Elective Laparoscopic Cholecystectomy

Laparoscopic cholecystectomy is now the gold standard technique for the treatment of gallstones disease. Although pain after laparoscopic cholecystectomy is less intense than after open cholecystectomy, some patients still experience considerable discomfort during the first 24 to 72 postoperative hours. The aim of this study is to evaluate the effect of intraperitoneal and port site instillation of local anaesthetics on pain relief in early postoperative period following laparoscopic cholecystectomy. Fifty patients undergoing elective laparoscopic cholecystectomy were consecutively included in this study and sample was divided into two groups. Following removal of gallbladder, Group A received 20 ml of 0.25% bupivacaine instilled in the right sub diaphragmatic space and 20 ml of 0.25% bupivacaine in divided doses at the trocar sites. The evaluation of postoperative pain was done at fixed time interval according to the numerical verbal scale and the dosage of narcotic analgesics consumed was also recorded. Mean pain scores at 6 hours and at 12 hours after surgery were 6.02 and 4.72 respectively, in the bupivacaine group compared with 8.44 and 6.08 respectively in the control group (p= <0.001 and <0.001). However, pain scores at 24 hours and 48 hours postoperatively and incidence of shoulder tip pain did not differ significantly between the two groups. The mean total narcotic analgesics used in study group was 1.91 as compared to 2.50 in the control group respectively and was found to be statistically significant (p= <0.001). Infiltration of bupivacaine in to port site and intraperitoneal space is simple, inexpensive and effective technique to minimize early postoperative pain and can be practiced for elective laparoscopic cholecystectomy.   DOI: 10.3329/medtoday.v22i1.5601 Medicine Today Vol.22(1) 2010. 24-28

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