Detection of Membranous Protein Alterations on BCG-activated Macrophages Involved in Contact-dependent Tumoricidal Processes

Yanni Lun; Lingbing Zhang; Shiming Sun; Dongmei Yan; Bairong Du; Xun Zhu

doi:10.4172/jpb.1000075

Detection of Membranous Protein Alterations on BCG-activated Macrophages Involved in Contact-dependent Tumoricidal Processes

Journal of Proteomics & Bioinformatics ◽

10.4172/jpb.1000075 ◽

2009 ◽

Vol 02 (04) ◽

pp. 175-184

Author(s):

Yanni Lun ◽

Lingbing Zhang ◽

Shiming Sun ◽

Dongmei Yan ◽

Bairong Du ◽

...

Keyword(s):

Activated Macrophages ◽

Protein Alterations ◽

Membranous Protein

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791: Endothelial Rehabilitation - The Impact of Chronic PDE5 Inhibitors on Erectile Function and Protein Alterations in Cavernous Tissue of Diabetic Rats

The Journal of Urology ◽

10.1016/s0022-5347(18)31031-0 ◽

2007 ◽

Vol 177 (4S) ◽

pp. 264-265

Author(s):

Ling De Young ◽

KokBin Lim ◽

Jeffery Carson ◽

Trustin Domes ◽

Mussa Al-Numi ◽

...

Keyword(s):

Erectile Function ◽

Diabetic Rats ◽

Pde5 Inhibitors ◽

Cavernous Tissue ◽

Protein Alterations ◽

The Impact

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Reparação óssea no implante dental

Full Dentistry in Science ◽

10.24077/2020;1245-6366 ◽

2020 ◽

Vol 12 (45) ◽

pp. 63-66

Author(s):

Halim Nagem Filho ◽

Reinaldo Francisco Maia ◽

Reinaldo Missaka ◽

Nasser Hussein Fares

Keyword(s):

Gene Expression ◽

Titanium Surface ◽

Close Contact ◽

The Other ◽

Main Function ◽

Indirect Interaction ◽

M2 Macrophages ◽

Activated Macrophages ◽

M1 Macrophages ◽

High Production

The osseointegration is the stable and functional union between the bone and a titanium surface. A new bone can be found on the surface of the implant about 1 week after its installation; the bone remodeling begins between 6 and 12 weeks and continues throughout life. After the implant insertion, depending on the energy of the surface, the plasma fluid immediately adheres, in close contact with the surface, promoting the adsorption of proteins and inducing the indirect interaction of the cells with the material. Macrophages are cells found in the tissues and originated from bone marrow monocytes. The M1 macrophages orchestrate the phagocytic phase in the inflammatory region and also produce inflammatory cytokines involved with the chronic inflammation and the cleaning of the wound and damaged tissues from bacteria. On the other hand, alternative-activated macrophages (M2) are activated by IL-10, the immune complex. Its main function consists on regulating negatively the inflammation through the secretion of the immunosuppressant IL-10. The M2 macrophages present involvement with the immunosuppression, besides having a low capacity for presenting antigens and high production of cytokines; these can be further divided into M2a, M2b, and M2c, based on the gene expression profile.

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